(15 nodes) High-density lipoprotein particle network (Electrophorus electricus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC113568398	Uncharacterized protein. (255 aa)
	LOC113589139	Uncharacterized protein. (248 aa)
	LOC113569847	Serum amyloid A protein; Major acute phase reactant. Apolipoprotein of the HDL complex. (110 aa)
	LOC113590495	Uncharacterized protein. (261 aa)
	LOC113578327	Uncharacterized protein. (258 aa)
	apoh	Uncharacterized protein. (355 aa)
	lcat	Lecithin-cholesterol acyltransferase. (449 aa)
	pltp	Uncharacterized protein. (486 aa)
	lipc	Lipase, hepatic a. (494 aa)
	ENSEEEP00000041503	Uncharacterized protein. (131 aa)
	ENSEEEP00000041505	Uncharacterized protein. (212 aa)
	LOC113571809	PLAT domain-containing protein. (528 aa)
	cetp	Cholesteryl ester transfer protein; Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL; Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family. (499 aa)
	apoe	Uncharacterized protein. (273 aa)
	LOC113568397	Uncharacterized protein. (279 aa)

Your Current Organism:

Electrophorus electricus

NCBI taxonomy Id: 8005
Other names: E. electricus, electric eel, electric knifefish

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSEEEP00000041503	LOC113568398	ENSEEEP00000041503	ENSEEEP00000013028	Uncharacterized protein.	Uncharacterized protein.	0.429
ENSEEEP00000041503	LOC113578327	ENSEEEP00000041503	ENSEEEP00000010330	Uncharacterized protein.	Uncharacterized protein.	0.429
ENSEEEP00000041503	apoh	ENSEEEP00000041503	ENSEEEP00000011158	Uncharacterized protein.	Uncharacterized protein.	0.662
ENSEEEP00000041505	LOC113568398	ENSEEEP00000041505	ENSEEEP00000013028	Uncharacterized protein.	Uncharacterized protein.	0.429
ENSEEEP00000041505	LOC113578327	ENSEEEP00000041505	ENSEEEP00000010330	Uncharacterized protein.	Uncharacterized protein.	0.429
ENSEEEP00000041505	apoh	ENSEEEP00000041505	ENSEEEP00000011158	Uncharacterized protein.	Uncharacterized protein.	0.662
LOC113568397	LOC113568398	ENSEEEP00000013030	ENSEEEP00000013028	Uncharacterized protein.	Uncharacterized protein.	0.755
LOC113568397	LOC113571809	ENSEEEP00000013030	ENSEEEP00000042278	Uncharacterized protein.	PLAT domain-containing protein.	0.436
LOC113568397	LOC113578327	ENSEEEP00000013030	ENSEEEP00000010330	Uncharacterized protein.	Uncharacterized protein.	0.759
LOC113568397	LOC113589139	ENSEEEP00000013030	ENSEEEP00000037339	Uncharacterized protein.	Uncharacterized protein.	0.679
LOC113568397	LOC113590495	ENSEEEP00000013030	ENSEEEP00000004862	Uncharacterized protein.	Uncharacterized protein.	0.621
LOC113568397	cetp	ENSEEEP00000013030	ENSEEEP00000047581	Uncharacterized protein.	Cholesteryl ester transfer protein; Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL; Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.	0.591
LOC113568397	lcat	ENSEEEP00000013030	ENSEEEP00000034769	Uncharacterized protein.	Lecithin-cholesterol acyltransferase.	0.456
LOC113568397	lipc	ENSEEEP00000013030	ENSEEEP00000038268	Uncharacterized protein.	Lipase, hepatic a.	0.436
LOC113568397	pltp	ENSEEEP00000013030	ENSEEEP00000015334	Uncharacterized protein.	Uncharacterized protein.	0.464
LOC113568398	ENSEEEP00000041503	ENSEEEP00000013028	ENSEEEP00000041503	Uncharacterized protein.	Uncharacterized protein.	0.429
LOC113568398	ENSEEEP00000041505	ENSEEEP00000013028	ENSEEEP00000041505	Uncharacterized protein.	Uncharacterized protein.	0.429
LOC113568398	LOC113568397	ENSEEEP00000013028	ENSEEEP00000013030	Uncharacterized protein.	Uncharacterized protein.	0.755
LOC113568398	apoe	ENSEEEP00000013028	ENSEEEP00000013154	Uncharacterized protein.	Uncharacterized protein.	0.830
LOC113568398	apoh	ENSEEEP00000013028	ENSEEEP00000011158	Uncharacterized protein.	Uncharacterized protein.	0.653