39 items (Electrophorus electricus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC113573801	Transforming growth factor beta; Belongs to the TGF-beta family. (379 aa)
	rad1	Uncharacterized protein. (279 aa)
	sfrp2	Uncharacterized protein. (291 aa)
	gadd45b	Ribosomal_L7Ae domain-containing protein. (162 aa)
	rhno1	Uncharacterized protein. (308 aa)
	ect2	Epithelial cell transforming 2. (975 aa)
	ENSEEEP00000050260	Deoxyribonuclease 1 like 4, tandem duplicate 2. (243 aa)
	LOC113583726	Deoxyribonuclease; Belongs to the DNase I family. (267 aa)
	tank	TBD domain-containing protein. (343 aa)
	bard1	BRCA1 associated RING domain 1. (689 aa)
	chek2	Uncharacterized protein. (526 aa)
	LOC113576847	RING-type domain-containing protein. (995 aa)
	xrcc5	Ku domain-containing protein. (740 aa)
	fbxo4	F-box protein 4. (371 aa)
	sirt1	Deacetylase sirtuin-type domain-containing protein. (729 aa)
	blm	BLM RecQ like helicase. (1281 aa)
	rad51ap1	RAD51_interact domain-containing protein. (230 aa)
	atr	ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2627 aa)
	ENSEEEP00000032310	ATM serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (3024 aa)
	rad9a	Cell cycle checkpoint control protein; Belongs to the rad9 family. (386 aa)
	ENSEEEP00000031234	ELK1, member of ETS oncogene family. (423 aa)
	itgb6	Integrin beta; Belongs to the integrin beta chain family. (764 aa)
	ino80	Uncharacterized protein. (1128 aa)
	lig4	DNA ligase. (909 aa)
	xrcc6	Uncharacterized protein. (627 aa)
	ENSEEEP00000023290	RAD9 checkpoint clamp component B. (181 aa)
	spidr	DUF4503 domain-containing protein. (573 aa)
	LOC113582267	Breast cancer 2, early onset. (2391 aa)
	rad51	DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (339 aa)
	kdm1a	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (859 aa)
	LOC113580065	Protein kinase domain-containing protein. (462 aa)
	cdca7l	Cell division cycle associated 7b. (425 aa)
	cdca7	zf-4CXXC_R1 domain-containing protein. (406 aa)
	ENSEEEP00000009645	Pkinase_Tyr domain-containing protein. (238 aa)
	LOC113581577	Uncharacterized protein. (355 aa)
	LOC113571516	Uncharacterized protein. (221 aa)
	LOC113590492	Transforming growth factor beta; Belongs to the TGF-beta family. (379 aa)
	LOC113589335	Ribosomal_L7Ae domain-containing protein. (159 aa)
	zmpste24	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (474 aa)

Your Current Organism:

Electrophorus electricus

NCBI taxonomy Id: 8005
Other names: E. electricus, electric eel, electric knifefish

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSEEEP00000009645	LOC113580065	ENSEEEP00000009645	ENSEEEP00000012335	Pkinase_Tyr domain-containing protein.	Protein kinase domain-containing protein.	0.901
ENSEEEP00000023290	ENSEEEP00000032310	ENSEEEP00000023290	ENSEEEP00000032310	RAD9 checkpoint clamp component B.	ATM serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	0.876
ENSEEEP00000023290	LOC113576847	ENSEEEP00000023290	ENSEEEP00000047536	RAD9 checkpoint clamp component B.	RING-type domain-containing protein.	0.635
ENSEEEP00000023290	LOC113582267	ENSEEEP00000023290	ENSEEEP00000018632	RAD9 checkpoint clamp component B.	Breast cancer 2, early onset.	0.564
ENSEEEP00000023290	atr	ENSEEEP00000023290	ENSEEEP00000033278	RAD9 checkpoint clamp component B.	ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	0.832
ENSEEEP00000023290	bard1	ENSEEEP00000023290	ENSEEEP00000049245	RAD9 checkpoint clamp component B.	BRCA1 associated RING domain 1.	0.633
ENSEEEP00000023290	blm	ENSEEEP00000023290	ENSEEEP00000035037	RAD9 checkpoint clamp component B.	BLM RecQ like helicase.	0.730
ENSEEEP00000023290	chek2	ENSEEEP00000023290	ENSEEEP00000047638	RAD9 checkpoint clamp component B.	Uncharacterized protein.	0.649
ENSEEEP00000023290	lig4	ENSEEEP00000023290	ENSEEEP00000024668	RAD9 checkpoint clamp component B.	DNA ligase.	0.409
ENSEEEP00000023290	rad1	ENSEEEP00000023290	ENSEEEP00000052483	RAD9 checkpoint clamp component B.	Uncharacterized protein.	0.972
ENSEEEP00000023290	rad51	ENSEEEP00000023290	ENSEEEP00000017370	RAD9 checkpoint clamp component B.	DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...]	0.759
ENSEEEP00000023290	rhno1	ENSEEEP00000023290	ENSEEEP00000051215	RAD9 checkpoint clamp component B.	Uncharacterized protein.	0.791
ENSEEEP00000023290	xrcc5	ENSEEEP00000023290	ENSEEEP00000044169	RAD9 checkpoint clamp component B.	Ku domain-containing protein.	0.442
ENSEEEP00000023290	xrcc6	ENSEEEP00000023290	ENSEEEP00000023730	RAD9 checkpoint clamp component B.	Uncharacterized protein.	0.442
ENSEEEP00000032310	ENSEEEP00000023290	ENSEEEP00000032310	ENSEEEP00000023290	ATM serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	RAD9 checkpoint clamp component B.	0.876
ENSEEEP00000032310	LOC113576847	ENSEEEP00000032310	ENSEEEP00000047536	ATM serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	RING-type domain-containing protein.	0.960
ENSEEEP00000032310	LOC113582267	ENSEEEP00000032310	ENSEEEP00000018632	ATM serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	Breast cancer 2, early onset.	0.890
ENSEEEP00000032310	LOC113589335	ENSEEEP00000032310	ENSEEEP00000004196	ATM serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	Ribosomal_L7Ae domain-containing protein.	0.403
ENSEEEP00000032310	atr	ENSEEEP00000032310	ENSEEEP00000033278	ATM serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	0.999
ENSEEEP00000032310	bard1	ENSEEEP00000032310	ENSEEEP00000049245	ATM serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	BRCA1 associated RING domain 1.	0.920