(26 nodes) Mixed, incl. mRNA decay by 5 to 3 exoribonuclease, and Scd6-like Sm domain network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	dcp1a	Decapping mRNA 1A. (491 aa)
	EIF4ENIF1	Eukaryotic translation initiation factor 4E nuclear import factor 1. (953 aa)
	patl1	PAT1 homolog 1, processing body mRNA decay factor. (734 aa)
	dcp1b	Decapping mRNA 1B. (631 aa)
	yjefn3	YjeF N-terminal domain containing 3. (253 aa)
	lsm14a	LSM14A mRNA processing body assembly factor b. (463 aa)
	nudt8	Nudix hydrolase domain-containing protein. (390 aa)
	arhgap20	Uncharacterized protein. (974 aa)
	Lsm14b	LSM14 domain-containing protein. (87 aa)
	LSM14B	Uncharacterized protein. (244 aa)
	LOC103466988	Si:dkey-6n6.2. (318 aa)
	ENSPREP00000013186	Uncharacterized protein. (199 aa)
	naxe	NAD(P)H-hydrate epimerase; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX. (306 aa)
	dcp2	Decapping mRNA 2. (398 aa)
	nudt3	Nudix (nucleoside diphosphate linked moiety X)-type motif 3b. (178 aa)
	nudt7	Nudix (nucleoside diphosphate linked moiety X)-type motif 7. (245 aa)
	edc3	Enhancer of mRNA decapping 3 homolog (S. cerevisiae). (478 aa)
	ddx6	DEAD (Asp-Glu-Ala-Asp) box helicase 6; Belongs to the DEAD box helicase family. (482 aa)
	LSM14B-2	LSM14 domain-containing protein. (154 aa)
	LOC103466382	LSM14A mRNA processing body assembly factor a. (480 aa)
	LOC103466095	Nudix (nucleoside diphosphate linked moiety X)-type motif 4a. (181 aa)
	xrn1	5'-3' exoribonuclease 1. (1705 aa)
	LOC103474517	Zgc:114130. (430 aa)
	edc4	Enhancer of mRNA decapping 4. (1333 aa)
	naxd	ATP-dependent (S)-NAD(P)H-hydrate dehydratase; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. (647 aa)
	patl2	PAT1 homolog 2. (593 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EIF4ENIF1	ENSPREP00000013186	ENSPREP00000003290	ENSPREP00000013186	Eukaryotic translation initiation factor 4E nuclear import factor 1.	Uncharacterized protein.	0.945
EIF4ENIF1	LOC103466382	ENSPREP00000003290	ENSPREP00000024942	Eukaryotic translation initiation factor 4E nuclear import factor 1.	LSM14A mRNA processing body assembly factor a.	0.885
EIF4ENIF1	LSM14B	ENSPREP00000003290	ENSPREP00000011510	Eukaryotic translation initiation factor 4E nuclear import factor 1.	Uncharacterized protein.	0.785
EIF4ENIF1	LSM14B-2	ENSPREP00000003290	ENSPREP00000024430	Eukaryotic translation initiation factor 4E nuclear import factor 1.	LSM14 domain-containing protein.	0.785
EIF4ENIF1	Lsm14b	ENSPREP00000003290	ENSPREP00000011477	Eukaryotic translation initiation factor 4E nuclear import factor 1.	LSM14 domain-containing protein.	0.785
EIF4ENIF1	ddx6	ENSPREP00000003290	ENSPREP00000023831	Eukaryotic translation initiation factor 4E nuclear import factor 1.	DEAD (Asp-Glu-Ala-Asp) box helicase 6; Belongs to the DEAD box helicase family.	0.945
EIF4ENIF1	edc3	ENSPREP00000003290	ENSPREP00000023739	Eukaryotic translation initiation factor 4E nuclear import factor 1.	Enhancer of mRNA decapping 3 homolog (S. cerevisiae).	0.490
EIF4ENIF1	edc4	ENSPREP00000003290	ENSPREP00000031668	Eukaryotic translation initiation factor 4E nuclear import factor 1.	Enhancer of mRNA decapping 4.	0.437
EIF4ENIF1	lsm14a	ENSPREP00000003290	ENSPREP00000011274	Eukaryotic translation initiation factor 4E nuclear import factor 1.	LSM14A mRNA processing body assembly factor b.	0.885
EIF4ENIF1	patl1	ENSPREP00000003290	ENSPREP00000005572	Eukaryotic translation initiation factor 4E nuclear import factor 1.	PAT1 homolog 1, processing body mRNA decay factor.	0.424
EIF4ENIF1	patl2	ENSPREP00000003290	ENSPREP00000034055	Eukaryotic translation initiation factor 4E nuclear import factor 1.	PAT1 homolog 2.	0.424
ENSPREP00000013186	EIF4ENIF1	ENSPREP00000013186	ENSPREP00000003290	Uncharacterized protein.	Eukaryotic translation initiation factor 4E nuclear import factor 1.	0.945
ENSPREP00000013186	LOC103466382	ENSPREP00000013186	ENSPREP00000024942	Uncharacterized protein.	LSM14A mRNA processing body assembly factor a.	0.810
ENSPREP00000013186	LSM14B	ENSPREP00000013186	ENSPREP00000011510	Uncharacterized protein.	Uncharacterized protein.	0.781
ENSPREP00000013186	LSM14B-2	ENSPREP00000013186	ENSPREP00000024430	Uncharacterized protein.	LSM14 domain-containing protein.	0.781
ENSPREP00000013186	Lsm14b	ENSPREP00000013186	ENSPREP00000011477	Uncharacterized protein.	LSM14 domain-containing protein.	0.781
ENSPREP00000013186	dcp1a	ENSPREP00000013186	ENSPREP00000000963	Uncharacterized protein.	Decapping mRNA 1A.	0.954
ENSPREP00000013186	dcp1b	ENSPREP00000013186	ENSPREP00000006140	Uncharacterized protein.	Decapping mRNA 1B.	0.953
ENSPREP00000013186	dcp2	ENSPREP00000013186	ENSPREP00000018031	Uncharacterized protein.	Decapping mRNA 2.	0.956
ENSPREP00000013186	ddx6	ENSPREP00000013186	ENSPREP00000023831	Uncharacterized protein.	DEAD (Asp-Glu-Ala-Asp) box helicase 6; Belongs to the DEAD box helicase family.	0.902