STRINGSTRING
ENSPREP00000030719 ENSPREP00000030719 pcsk1 pcsk1 AKIRIN2 AKIRIN2 zdhhc16 zdhhc16 tsc1 tsc1 ENSPREP00000032096 ENSPREP00000032096 chd8 chd8 LOC103472829 LOC103472829 mcph1 mcph1 NRGN NRGN tctn1 tctn1 LOC103459124 LOC103459124 arnt2 arnt2 lgr4 lgr4 ENSPREP00000003163 ENSPREP00000003163 emx2 emx2 fgf3 fgf3 LOC103473440 LOC103473440 btg1 btg1 LOC103470370 LOC103470370 scyl2 scyl2 pgap1 pgap1 ENSPREP00000001881 ENSPREP00000001881 e2f1 e2f1 bbs1 bbs1 ENSPREP00000001616 ENSPREP00000001616 msx1 msx1 zswim5 zswim5 LOC103464964 LOC103464964 LOC103477979 LOC103477979 BMERB1 BMERB1 dpcd dpcd sun2 sun2 LOC103456513 LOC103456513 pcm1 pcm1 ENSPREP00000033510 ENSPREP00000033510 LOC103481296 LOC103481296 ptchd1 ptchd1 LOC103475806 LOC103475806 LOC103474638 LOC103474638 dcx dcx lef1 lef1 gli3 gli3 foxg1 foxg1 LOC103475931 LOC103475931 LOC103482193 LOC103482193 lrrc45 lrrc45 LOC103462732 LOC103462732 Six3 Six3 aplp1 aplp1 LOC103477205 LOC103477205 ENSPREP00000005246 ENSPREP00000005246 vax2 vax2 lrrk2 lrrk2 smo smo gli2 gli2 LOC103474746 LOC103474746 LOC103472121 LOC103472121 LOC103471076 LOC103471076 LOC103475400 LOC103475400 ENSPREP00000006501 ENSPREP00000006501 zdhhc15 zdhhc15 fgf16 fgf16 atrx atrx ENSPREP00000006666 ENSPREP00000006666 kdm1a kdm1a LOC103481539 LOC103481539 LOC103461327 LOC103461327 LOC103471204 LOC103471204 tmem108 tmem108 ENSPREP00000007854 ENSPREP00000007854 Rtn4r Rtn4r Nrg3 Nrg3 xab2 xab2 efhc1 efhc1 SRF SRF arl13b arl13b LOC103457458 LOC103457458 fat4 fat4 bbs4 bbs4 notch1 notch1 crkl crkl ENSPREP00000009863 ENSPREP00000009863 sall1 sall1 bmp4 bmp4 Mycbp2 Mycbp2 ascl1 ascl1 ENSPREP00000010244 ENSPREP00000010244 LOC103477235 LOC103477235 LOC103465784 LOC103465784 mkks mkks aqp1 aqp1 ENSPREP00000010780 ENSPREP00000010780 ttc21b ttc21b rapgef2 rapgef2 ENSPREP00000011364 ENSPREP00000011364 cdk5 cdk5 LOC103474847 LOC103474847 tbr1 tbr1 axin1 axin1 gli1 gli1 LOC103462612 LOC103462612 ENSPREP00000012400 ENSPREP00000012400 numb numb mpp5 mpp5 LOC103473007 LOC103473007 srf srf BAX BAX shh shh mettl14 mettl14 lhx6 lhx6 LOC103457369 LOC103457369 ENSPREP00000013704 ENSPREP00000013704 crk crk LOC103460864 LOC103460864 wnt7b wnt7b LOC103467575 LOC103467575 nf2 nf2 ttc8 ttc8 clg14h21orf91 clg14h21orf91 ENSPREP00000014353 ENSPREP00000014353 LOC103475595 LOC103475595 hsd3b7 hsd3b7 lhx8 lhx8 ENSPREP00000015283 ENSPREP00000015283 pitx2 pitx2 uchl5 uchl5 ENSPREP00000015733 ENSPREP00000015733 LOC103480536 LOC103480536 epha4 epha4 ventx ventx LOC103468990 LOC103468990 LOC103475562 LOC103475562 LOC103465913 LOC103465913 LOC103468291 LOC103468291 Neurog1 Neurog1 htr6 htr6 ENSPREP00000017735 ENSPREP00000017735 LOC103477376 LOC103477376 lhx9 lhx9 fez1 fez1 ENSPREP00000018724 ENSPREP00000018724 cdk5r1 cdk5r1 med12 med12 LOC103479267 LOC103479267 LOC103474972 LOC103474972 LOC103457154 LOC103457154 ENSPREP00000019614 ENSPREP00000019614 gbx2 gbx2 vsx1 vsx1 lhx2 lhx2 pax6 pax6 bsx bsx LOC103461065 LOC103461065 zdhhc20 zdhhc20 LOC103474297 LOC103474297 sall3 sall3 ENSPREP00000021332 ENSPREP00000021332 draxin draxin LOC103476799 LOC103476799 nf1 nf1 arx arx LOC103471473 LOC103471473 LOC103482434 LOC103482434 LOC103471993 LOC103471993 trappc9 trappc9 ENSPREP00000022311 ENSPREP00000022311 lhx1 lhx1 LOC103479287 LOC103479287 TBX2 TBX2 ryk ryk six6 six6 LOC103461155 LOC103461155 ENSPREP00000023272 ENSPREP00000023272 xrcc1 xrcc1 ENSPREP00000023453 ENSPREP00000023453 LOC103460449 LOC103460449 ENSPREP00000023825 ENSPREP00000023825 RELN RELN Mib1 Mib1 ENSPREP00000025759 ENSPREP00000025759 nin nin LOC103478724 LOC103478724 LOC103465401 LOC103465401 ccdc85c ccdc85c ZSWIM6 ZSWIM6 SIM1 SIM1 LOC103476999 LOC103476999 DIXDC1 DIXDC1 wnt4 wnt4 rax rax LOC103473262 LOC103473262 LOC103472663 LOC103472663 ndnf ndnf lhx5 lhx5 LOC103477609 LOC103477609 LOC103476530 LOC103476530 ENSPREP00000027668 ENSPREP00000027668 Cep120 Cep120 otp otp slc1a2 slc1a2 agtpbp1 agtpbp1 gsx2 gsx2 LOC103477638 LOC103477638 SZT2 SZT2 Szt2 Szt2 disp1 disp1 cntn2 cntn2 ptchd4 ptchd4 nars1 nars1 fezf2 fezf2 rpgrip1l rpgrip1l WNT7A WNT7A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSPREP00000030719Uncharacterized protein. (708 aa)
pcsk1Proprotein convertase subtilisin/kexin type 1; Belongs to the peptidase S8 family. (782 aa)
AKIRIN2Akirin 2. (193 aa)
zdhhc16Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (384 aa)
tsc1TSC complex subunit 1b. (1243 aa)
ENSPREP00000032096LIM zinc-binding domain-containing protein. (71 aa)
chd8Chromodomain-helicase-DNA-binding protein 8; DNA helicase that acts as a chromatin remodeling factor and regulates transcription. Acts as a transcription repressor by remodeling chromatin structure and recruiting histone H1 to target genes. Suppresses p53/TP53-mediated apoptosis by recruiting histone H1 and preventing p53/TP53 transactivation activity. Acts as a negative regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) activity. Negatively regulates CTNNB1-targeted gene expression by being recruited specifically to the promoter regions of several CTNNB1 responsive [...] (2620 aa)
LOC103472829Uncharacterized protein. (298 aa)
mcph1Microcephalin 1. (808 aa)
NRGNNeurogranin. (90 aa)
tctn1DUF1619 domain-containing protein. (519 aa)
LOC103459124Si:ch73-352p4.8. (487 aa)
arnt2Aryl-hydrocarbon receptor nuclear translocator 2. (679 aa)
lgr4Leucine-rich repeat containing G protein-coupled receptor 4. (913 aa)
ENSPREP00000003163Paired box 4. (287 aa)
emx2Empty spiracles homeobox 2. (247 aa)
fgf3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (236 aa)
LOC103473440Notch receptor 1a. (2478 aa)
btg1B-cell translocation gene 1, anti-proliferative. (148 aa)
LOC103470370TACC_C domain-containing protein. (503 aa)
scyl2SCY1 like pseudokinase 2. (914 aa)
pgap1Post-GPI attachment to proteins 1. (931 aa)
ENSPREP00000001881T-box transcription factor 2a. (572 aa)
e2f1E2F transcription factor 1. (477 aa)
bbs1Bardet-Biedl syndrome 1. (583 aa)
ENSPREP00000001616LIM zinc-binding domain-containing protein. (57 aa)
msx1Muscle segment homeobox 1a. (281 aa)
zswim5Zinc finger, SWIM-type containing 5. (1160 aa)
LOC103464964Transforming, acidic coiled-coil containing protein 1. (927 aa)
LOC103477979Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1; Belongs to the 3-beta-HSD family. (374 aa)
BMERB1BMERB domain containing 1. (197 aa)
dpcdDeleted in primary ciliary dyskinesia homolog (mouse). (202 aa)
sun2SUN domain-containing protein. (647 aa)
LOC103456513Uncharacterized protein. (883 aa)
pcm1Pericentriolar material 1. (2112 aa)
ENSPREP00000033510Uncharacterized protein. (266 aa)
LOC103481296Uncharacterized protein. (562 aa)
ptchd1Patched domain containing 1. (969 aa)
LOC103475806Activating transcription factor 5a. (505 aa)
LOC103474638Bone morphogenetic protein 16. (512 aa)
dcxUncharacterized protein. (359 aa)
lef1Lymphoid enhancer-binding factor 1. (422 aa)
gli3Uncharacterized protein. (1354 aa)
foxg1Forkhead box G1a. (346 aa)
LOC103475931SIX homeobox 7. (260 aa)
LOC103482193Cytochrome P450, family 26, subfamily A, polypeptide 1; Belongs to the cytochrome P450 family. (506 aa)
lrrc45Leucine rich repeat containing 45. (674 aa)
LOC103462732Amino acid transporter. (559 aa)
Six3SIX homeobox 3a. (341 aa)
aplp1Amyloid beta (A4) precursor-like protein 1. (712 aa)
LOC103477205TACC_C domain-containing protein. (3266 aa)
ENSPREP00000005246Protein kinase domain-containing protein. (250 aa)
vax2Ventral anterior homeobox 2. (304 aa)
lrrk2Leucine-rich repeat kinase 2. (2573 aa)
smoSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (811 aa)
gli2GLI family zinc finger 2a. (1452 aa)
LOC103474746Fork-head domain-containing protein. (389 aa)
LOC103472121BTB (POZ) domain containing 3a. (410 aa)
LOC103471076Uncharacterized protein. (136 aa)
LOC103475400Janus kinase and microtubule interacting protein 2. (669 aa)
ENSPREP00000006501Uncharacterized protein. (235 aa)
zdhhc15Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (357 aa)
fgf16Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (190 aa)
atrxATRX chromatin remodeler. (2188 aa)
ENSPREP00000006666BHLH domain-containing protein. (76 aa)
kdm1aLysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (855 aa)
LOC103481539SIX homeobox 3b. (277 aa)
LOC103461327Uncharacterized protein. (406 aa)
LOC103471204Ubiquinol-cytochrome c reductase, complex III subunit VII. (82 aa)
tmem108Transmembrane protein 108. (416 aa)
ENSPREP00000007854Uncharacterized protein. (143 aa)
Rtn4rReticulon 4 receptor. (452 aa)
Nrg3EGF-like domain-containing protein. (95 aa)
xab2XPA binding protein 2. (912 aa)
efhc1EF-hand domain (C-terminal) containing 1. (551 aa)
SRFSerum response factor. (243 aa)
arl13bADP-ribosylation factor-like 13b. (405 aa)
LOC103457458Uncharacterized protein. (763 aa)
fat4FAT atypical cadherin 4. (4974 aa)
bbs4Bardet-Biedl syndrome 4. (520 aa)
notch1Notch receptor 1b. (2491 aa)
crklV-crk avian sarcoma virus CT10 oncogene homolog-like. (310 aa)
ENSPREP00000009863Si:ch211-236k19.2. (307 aa)
sall1Spalt-like transcription factor 1a. (1309 aa)
bmp4Bone morphogenetic protein 4. (480 aa)
Mycbp2RING-type domain-containing protein. (497 aa)
ascl1Achaete-scute family bHLH transcription factor 1a. (200 aa)
ENSPREP00000010244Uncharacterized protein. (446 aa)
LOC103477235BTB (POZ) domain containing 3b. (523 aa)
LOC103465784Uncharacterized protein. (393 aa)
mkksMcKusick-Kaufman syndrome. (576 aa)
aqp1Aquaporin 1a (Colton blood group), tandem duplicate 1; Belongs to the MIP/aquaporin (TC 1.A.8) family. (268 aa)
ENSPREP00000010780Aquaporin 1a (Colton blood group), tandem duplicate 1; Belongs to the MIP/aquaporin (TC 1.A.8) family. (176 aa)
ttc21bTetratricopeptide repeat domain 21B. (1317 aa)
rapgef2Rap guanine nucleotide exchange factor (GEF) 2. (1615 aa)
ENSPREP00000011364Kinesin family member 14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1074 aa)
cdk5Cyclin-dependent kinase 5. (262 aa)
LOC103474847NUMB like endocytic adaptor protein. (751 aa)
tbr1T-box brain transcription factor 1b. (678 aa)
axin1Axin 1. (850 aa)
gli1GLI family zinc finger 1. (1488 aa)
LOC103462612Uncharacterized protein; Belongs to the semaphorin family. (615 aa)
ENSPREP00000012400Uncharacterized protein. (550 aa)
numbNUMB endocytic adaptor protein. (661 aa)
mpp5Membrane protein, palmitoylated 5b (MAGUK p55 subfamily member 5); Belongs to the MAGUK family. (650 aa)
LOC103473007Cyclin-dependent kinase 5 activator. (321 aa)
srfSerum response factor b. (570 aa)
BAXBCL2 associated X, apoptosis regulator. (191 aa)
shhHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (427 aa)
mettl14Methyltransferase like 14; Belongs to the MT-A70-like family. (455 aa)
lhx6LIM homeobox 6. (375 aa)
LOC103457369Akirin 2. (179 aa)
ENSPREP00000013704Uncharacterized protein. (155 aa)
crkCRK proto-oncogene, adaptor protein. (315 aa)
LOC103460864Uncharacterized protein; Belongs to the MAGUK family. (538 aa)
wnt7bProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
LOC103467575Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (364 aa)
nf2Neurofibromin 2b (merlin). (615 aa)
ttc8Tetratricopeptide repeat domain 8. (513 aa)
clg14h21orf91Zgc:110006. (287 aa)
ENSPREP00000014353Semaphorin 7A; Belongs to the semaphorin family. (366 aa)
LOC103475595Reticulon 4 receptor-like 1a. (454 aa)
hsd3b7Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase; Belongs to the 3-beta-HSD family. (367 aa)
lhx8LIM homeobox 8b. (364 aa)
ENSPREP00000015283Reticulon 4 receptor-like 1b. (451 aa)
pitx2Homeobox protein. (312 aa)
uchl5Ubiquitin carboxyl-terminal hydrolase. (339 aa)
ENSPREP00000015733DIX domain containing 1a. (202 aa)
LOC103480536Methyltransferase like 3; Belongs to the MT-A70-like family. (287 aa)
epha4Eph receptor A4, like. (979 aa)
ventxHomeobox domain-containing protein. (224 aa)
LOC103468990Amino acid transporter. (675 aa)
LOC103475562Doublecortin-like kinase 1a. (722 aa)
LOC103465913Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
LOC103468291Cyclin-dependent kinase 5 activator. (334 aa)
Neurog1Neurogenin 1. (202 aa)
htr65-hydroxytryptamine (serotonin) receptor 6; Belongs to the G-protein coupled receptor 1 family. (468 aa)
ENSPREP00000017735Uncharacterized protein. (748 aa)
LOC103477376Forkhead box G1d. (344 aa)
lhx9LIM homeobox 9. (505 aa)
fez1Fasciculation and elongation protein zeta 1 (zygin I). (398 aa)
ENSPREP00000018724Uncharacterized protein. (624 aa)
cdk5r1Cyclin-dependent kinase 5 activator. (450 aa)
med12Mediator complex subunit 12. (2052 aa)
LOC103479267Uncharacterized protein. (1084 aa)
LOC103474972Doublecortin-like kinase 1b. (747 aa)
LOC103457154Uncharacterized protein. (689 aa)
ENSPREP00000019614Uncharacterized protein. (181 aa)
gbx2Gastrulation brain homeobox 2. (339 aa)
vsx1Uncharacterized protein. (275 aa)
lhx2LIM homeobox 2b. (363 aa)
pax6Paired box 6b. (431 aa)
bsxBrain-specific homeobox. (224 aa)
LOC103461065DUF1619 domain-containing protein. (354 aa)
zdhhc20Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (372 aa)
LOC103474297Activating transcription factor 5b. (470 aa)
sall3Spalt-like transcription factor 3a. (1253 aa)
ENSPREP00000021332Uncharacterized protein. (148 aa)
draxinDraxin; Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord; Belongs to the draxin family. (378 aa)
LOC103476799Dickkopf WNT signaling pathway inhibitor 1a. (242 aa)
nf1Neurofibromin 1b. (2742 aa)
arxAristaless related homeobox a. (469 aa)
LOC103471473Empty spiracles homeobox 3. (246 aa)
LOC103482434Forkhead box H1. (633 aa)
LOC103471993T-box transcription factor Ta. (421 aa)
trappc9Trafficking protein particle complex 9. (1092 aa)
ENSPREP00000022311Transforming, acidic coiled-coil containing protein 3. (781 aa)
lhx1LIM homeobox 1a. (374 aa)
LOC103479287LIM homeobox 8a. (316 aa)
TBX2T-box transcription factor 2. (686 aa)
rykReceptor like tyrosine kinase. (632 aa)
six6SIX homeobox 6a. (245 aa)
LOC103461155Neurofibromin 2a (merlin). (394 aa)
ENSPREP00000023272Uncharacterized protein. (267 aa)
xrcc1X-ray repair complementing defective repair in Chinese hamster cells 1. (619 aa)
ENSPREP00000023453P/Homo B domain-containing protein; Belongs to the peptidase S8 family. (755 aa)
LOC103460449Neuropilin; Belongs to the neuropilin family. (936 aa)
ENSPREP00000023825SH2 domain-containing protein. (93 aa)
RELNReelin. (3446 aa)
Mib1Mindbomb E3 ubiquitin protein ligase 1. (994 aa)
ENSPREP00000025759Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (332 aa)
ninNinein (GSK3B interacting protein). (2145 aa)
LOC103478724Aryl hydrocarbon receptor nuclear translocator. (761 aa)
LOC103465401GLUCAGON domain-containing protein. (195 aa)
ccdc85cCoiled-coil domain containing 85C. (401 aa)
ZSWIM6Zinc finger SWIM-type containing 6. (1133 aa)
SIM1SIM bHLH transcription factor 1a. (740 aa)
LOC103476999Homeobox domain-containing protein. (153 aa)
DIXDC1DIX domain containing 1. (451 aa)
wnt4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
raxRetinal homeobox gene 3. (310 aa)
LOC103473262Zinc finger, SWIM-type containing 6. (1134 aa)
LOC103472663Eomesodermin homolog a. (651 aa)
ndnfNeuron-derived neurotrophic factor. (571 aa)
lhx5LIM homeobox 5. (395 aa)
LOC103477609Brevican. (1226 aa)
LOC103476530Homeobox protein. (294 aa)
ENSPREP00000027668Centrosomal protein 120. (452 aa)
Cep120DUF3668 domain-containing protein. (223 aa)
otpOrthopedia homeobox. (326 aa)
slc1a2Amino acid transporter. (537 aa)
agtpbp1ATP/GTP binding protein 1. (1264 aa)
gsx2GS homeobox 2. (239 aa)
LOC103477638Si:ch211-113g11.6; Belongs to the semaphorin family. (609 aa)
SZT2SZT2 subunit of KICSTOR complex. (2242 aa)
Szt2Uncharacterized protein. (100 aa)
disp1Dispatched homolog 1 (Drosophila). (1577 aa)
cntn2Contactin 2. (1034 aa)
ptchd4Patched domain containing 4. (921 aa)
nars1Asparaginyl-tRNA synthetase. (559 aa)
fezf2FEZ family zinc finger 2. (346 aa)
rpgrip1lRPGRIP1 like. (1044 aa)
WNT7AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (396 aa)
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
Server load: low (40%) [HD]