(11 nodes) Dendritic spine morphogenesis network (Poecilia reticulata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	dock10	Dedicator of cytokinesis 10; Belongs to the DOCK family. (2188 aa)
	CDC42	Cell division cycle 42. (191 aa)
	LOC103479062	Eph receptor B3a. (959 aa)
	ephb3	Receptor protein-tyrosine kinase. (1013 aa)
	shank1	SH3 and multiple ankyrin repeat domains 1. (834 aa)
	Shank1	SAM domain-containing protein. (1628 aa)
	LOC103466031	SH3 and multiple ankyrin repeat domains 3a. (1984 aa)
	LOC103463007	SH3 and multiple ankyrin repeat domains 2a. (1709 aa)
	LOC103481054	Uncharacterized protein. (2065 aa)
	LOC103465423	Cell division cycle 42. (191 aa)
	prmt3	Protein arginine methyltransferase 3; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (542 aa)

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDC42	dock10	ENSPREP00000005959	ENSPREP00000033413	Cell division cycle 42.	Dedicator of cytokinesis 10; Belongs to the DOCK family.	0.897
LOC103465423	dock10	ENSPREP00000026666	ENSPREP00000033413	Cell division cycle 42.	Dedicator of cytokinesis 10; Belongs to the DOCK family.	0.897
Shank1	shank1	ENSPREP00000015974	ENSPREP00000015953	SAM domain-containing protein.	SH3 and multiple ankyrin repeat domains 1.	0.896
dock10	CDC42	ENSPREP00000033413	ENSPREP00000005959	Dedicator of cytokinesis 10; Belongs to the DOCK family.	Cell division cycle 42.	0.897
dock10	LOC103465423	ENSPREP00000033413	ENSPREP00000026666	Dedicator of cytokinesis 10; Belongs to the DOCK family.	Cell division cycle 42.	0.897
shank1	Shank1	ENSPREP00000015953	ENSPREP00000015974	SH3 and multiple ankyrin repeat domains 1.	SAM domain-containing protein.	0.896