(70 nodes) Valine, leucine and isoleucine degradation, and Fatty acid oxidation network (Xiphophorus maculatus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	hpdl	4-hydroxyphenylpyruvate dioxygenase. (442 aa)
	LOC102231519	Si:ch211-198n5.11. (565 aa)
	LOC102233930	SAP domain-containing protein. (981 aa)
	ilvbl	IlvB (bacterial acetolactate synthase)-like; Belongs to the TPP enzyme family. (625 aa)
	etfdh	Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. (622 aa)
	acad11	Acyl-CoA dehydrogenase family, member 11. (769 aa)
	mccc2	Methylcrotonoyl-CoA carboxylase 2 (beta). (564 aa)
	aacs	Acetoacetyl-CoA synthetase. (676 aa)
	etfa	Electron transfer flavoprotein subunit alpha. (333 aa)
	LOC102236075	Zgc:101569; Belongs to the enoyl-CoA hydratase/isomerase family. (309 aa)
	acox1	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (661 aa)
	hadhb	Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta; Belongs to the thiolase-like superfamily. Thiolase family. (473 aa)
	LOC102230203	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (497 aa)
	rpp14	Ribonuclease P/MRP subunit p14. (144 aa)
	acss2	Acyl-CoA synthetase short chain family member 2. (695 aa)
	bdh1	3-hydroxybutyrate dehydrogenase, type 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (361 aa)
	pccb	Propionyl-CoA carboxylase subunit beta. (561 aa)
	hao1	Hydroxyacid oxidase (glycolate oxidase) 1. (373 aa)
	LOC102236270	Malate synthase-like. (549 aa)
	acox3	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (692 aa)
	LOC102237393	Uncharacterized protein. (107 aa)
	ivd	Isovaleryl-CoA dehydrogenase. (417 aa)
	echs1	Enoyl CoA hydratase, short chain, 1, mitochondrial; Belongs to the enoyl-CoA hydratase/isomerase family. (291 aa)
	hacl1	2-hydroxyacyl-CoA lyase 1; Belongs to the TPP enzyme family. (572 aa)
	aldh5a1	Succinate-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (513 aa)
	acaa2	Acetyl-CoA acyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. (396 aa)
	pcca	Propionyl-CoA carboxylase subunit alpha. (711 aa)
	acadm	Acyl-CoA dehydrogenase medium chain. (422 aa)
	LOC102221845	Aldedh domain-containing protein. (529 aa)
	acadvl	Acyl-CoA dehydrogenase very long chain. (659 aa)
	hadha	Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha b; Belongs to the enoyl-CoA hydratase/isomerase family. (763 aa)
	stoml1	Stomatin (EPB72)-like 1. (411 aa)
	oxct1	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (527 aa)
	auh	AU RNA binding protein/enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (321 aa)
	acadsb	Acyl-CoA dehydrogenase short/branched chain. (441 aa)
	LOC102221886	Aldehyde dehydrogenase 9 family, member A1b; Belongs to the aldehyde dehydrogenase family. (520 aa)
	hmgcl	3-hydroxy-3-methylglutaryl-CoA lyase. (337 aa)
	LOC102226141	Acetyl-coenzyme A synthetase. (708 aa)
	acad8	Acyl-CoA dehydrogenase family, member 8. (419 aa)
	ENSXMAP00000022723	Uncharacterized protein. (234 aa)
	aldh3b1	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (469 aa)
	bdh2	3-hydroxybutyrate dehydrogenase, type 2. (245 aa)
	LOC102233725	Uncharacterized protein. (102 aa)
	acaa1	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. (425 aa)
	ech1	Enoyl CoA hydratase 1, peroxisomal; Belongs to the enoyl-CoA hydratase/isomerase family. (308 aa)
	etfb	Electron transfer flavoprotein subunit beta. (254 aa)
	ECHDC1	Ethylmalonyl-CoA decarboxylase 1; Belongs to the enoyl-CoA hydratase/isomerase family. (312 aa)
	ACADL	Acyl-CoA dehydrogenase long chain. (438 aa)
	acss3	Acyl-CoA synthetase short chain family member 3. (700 aa)
	hsd17b4	Hydroxysteroid (17-beta) dehydrogenase 4. (737 aa)
	lamp3	Methylcrotonoyl-CoA carboxylase 1 (alpha). (717 aa)
	Smim24	Uncharacterized protein. (99 aa)
	LOC102219664	Uncharacterized protein. (130 aa)
	eci1	Enoyl-CoA delta isomerase 1; Belongs to the enoyl-CoA hydratase/isomerase family. (298 aa)
	hmgcll1	3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1. (337 aa)
	LOC106700234	Acyl-CoA dehydrogenase long chain. (427 aa)
	LOC102218965	Zgc:85777. (434 aa)
	acads	Acyl-CoA dehydrogenase short chain. (405 aa)
	LOC102219361	3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. (326 aa)
	CDYL2	Chromodomain Y like 2. (524 aa)
	cpt2	Carnitine palmitoyltransferase 2; Belongs to the carnitine/choline acetyltransferase family. (683 aa)
	adhfe1	Alcohol dehydrogenase iron containing 1. (464 aa)
	ehhadh	Enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase; Belongs to the enoyl-CoA hydratase/isomerase family. (718 aa)
	abat	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (517 aa)
	LOC102224840	3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. (329 aa)
	echdc2	Enoyl CoA hydratase domain containing 2; Belongs to the enoyl-CoA hydratase/isomerase family. (332 aa)
	cat	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (527 aa)
	aldh6a1	Aldehyde dehydrogenase 6 family member A1. (526 aa)
	acat1	Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. (473 aa)
	hadh	Hydroxyacyl-CoA dehydrogenase. (318 aa)

Your Current Organism:

Xiphophorus maculatus

NCBI taxonomy Id: 8083
Other names: Platypoecilus maculatus, X. maculatus, southern platyfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACADL	CDYL2	ENSXMAP00000028877	ENSXMAP00000035764	Acyl-CoA dehydrogenase long chain.	Chromodomain Y like 2.	0.583
ACADL	ECHDC1	ENSXMAP00000028877	ENSXMAP00000028349	Acyl-CoA dehydrogenase long chain.	Ethylmalonyl-CoA decarboxylase 1; Belongs to the enoyl-CoA hydratase/isomerase family.	0.631
ACADL	LOC102219664	ENSXMAP00000028877	ENSXMAP00000030764	Acyl-CoA dehydrogenase long chain.	Uncharacterized protein.	0.597
ACADL	LOC102226141	ENSXMAP00000028877	ENSXMAP00000020932	Acyl-CoA dehydrogenase long chain.	Acetyl-coenzyme A synthetase.	0.488
ACADL	LOC102231519	ENSXMAP00000028877	ENSXMAP00000000716	Acyl-CoA dehydrogenase long chain.	Si:ch211-198n5.11.	0.684
ACADL	LOC102233725	ENSXMAP00000028877	ENSXMAP00000026746	Acyl-CoA dehydrogenase long chain.	Uncharacterized protein.	0.597
ACADL	LOC102236075	ENSXMAP00000028877	ENSXMAP00000006039	Acyl-CoA dehydrogenase long chain.	Zgc:101569; Belongs to the enoyl-CoA hydratase/isomerase family.	0.631
ACADL	LOC102236270	ENSXMAP00000028877	ENSXMAP00000010958	Acyl-CoA dehydrogenase long chain.	Malate synthase-like.	0.817
ACADL	LOC102237393	ENSXMAP00000028877	ENSXMAP00000013053	Acyl-CoA dehydrogenase long chain.	Uncharacterized protein.	0.597
ACADL	aacs	ENSXMAP00000028877	ENSXMAP00000003003	Acyl-CoA dehydrogenase long chain.	Acetoacetyl-CoA synthetase.	0.488
ACADL	acaa1	ENSXMAP00000028877	ENSXMAP00000027068	Acyl-CoA dehydrogenase long chain.	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	0.968
ACADL	acaa2	ENSXMAP00000028877	ENSXMAP00000014614	Acyl-CoA dehydrogenase long chain.	Acetyl-CoA acyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family.	0.964
ACADL	acad11	ENSXMAP00000028877	ENSXMAP00000002605	Acyl-CoA dehydrogenase long chain.	Acyl-CoA dehydrogenase family, member 11.	0.435
ACADL	acadm	ENSXMAP00000028877	ENSXMAP00000015011	Acyl-CoA dehydrogenase long chain.	Acyl-CoA dehydrogenase medium chain.	0.946
ACADL	acads	ENSXMAP00000028877	ENSXMAP00000035445	Acyl-CoA dehydrogenase long chain.	Acyl-CoA dehydrogenase short chain.	0.914
ACADL	acadsb	ENSXMAP00000028877	ENSXMAP00000016686	Acyl-CoA dehydrogenase long chain.	Acyl-CoA dehydrogenase short/branched chain.	0.915
ACADL	acadvl	ENSXMAP00000028877	ENSXMAP00000015518	Acyl-CoA dehydrogenase long chain.	Acyl-CoA dehydrogenase very long chain.	0.932
ACADL	acat1	ENSXMAP00000028877	ENSXMAP00000038734	Acyl-CoA dehydrogenase long chain.	Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	0.597
ACADL	acox1	ENSXMAP00000028877	ENSXMAP00000006077	Acyl-CoA dehydrogenase long chain.	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.	0.931
ACADL	acox3	ENSXMAP00000028877	ENSXMAP00000011887	Acyl-CoA dehydrogenase long chain.	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.	0.933