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ccnb2 ccnb2 ccna1 ccna1 ar-alpha ar-alpha dbf4 dbf4 LOC100049233 LOC100049233 skp2 skp2 ccnb1 ccnb1 e2f2 e2f2 orc3 orc3 ccnb3 ccnb3 LOC110014991 LOC110014991 cdkn2c cdkn2c cdc6 cdc6 pcna pcna ENSORLP00000039885 ENSORLP00000039885 PPP2R5C PPP2R5C esr1 esr1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ccnb2G2/mitotic-specific cyclin-B2; Essential for the control of the cell cycle at the G2/M (mitosis) transition; Belongs to the cyclin family. Cyclin AB subfamily. (387 aa)
ccna1Cyclin A1; Belongs to the cyclin family. (413 aa)
ar-alphaUncharacterized protein. (687 aa)
dbf4DBF4 zinc finger. (594 aa)
LOC100049233Androgen receptor beta subtype. (744 aa)
skp2S-phase kinase-associated protein 2, E3 ubiquitin protein ligase. (421 aa)
ccnb1G2/mitotic-specific cyclin-B1; Essential for the control of the cell cycle at the G2/M (mitosis) transition; Belongs to the cyclin family. Cyclin AB subfamily. (404 aa)
e2f2Si:ch211-160f23.5. (442 aa)
orc3Origin recognition complex, subunit 3. (719 aa)
ccnb3Cyclin B3; Belongs to the cyclin family. (425 aa)
LOC110014991Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (76 aa)
cdkn2cCyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4). (168 aa)
cdc6Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (568 aa)
pcnaProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (298 aa)
ENSORLP00000039885Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (107 aa)
PPP2R5CSerine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (567 aa)
esr1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (634 aa)
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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