Your Input: | |
| | pold1 | DNA polymerase. (1104 aa) |
| | ENSAPOP00000034731 | Uncharacterized protein. (104 aa) |
| | sirt6 | Sirtuin 6. (286 aa) |
| | rad51 | DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (338 aa) |
| | rcbtb2 | Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2. (527 aa) |
| | LOC110971723 | RAD51 paralog C. (346 aa) |
| | mre11 | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (672 aa) |
| | ube2i | Ubiquitin-conjugating enzyme E2Ia; Belongs to the ubiquitin-conjugating enzyme family. (158 aa) |
| | rad1 | RAD1 homolog (S. pombe). (278 aa) |
| | top3a | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (1026 aa) |
| | RPA1 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (691 aa) |
| | LOC110971106 | Histone H2B; Belongs to the histone H2B family. (118 aa) |
| | ENSAPOP00000031672 | Histone H2A; Belongs to the histone H2A family. (233 aa) |
| | ENSAPOP00000031054 | annotation not available (53 aa) |
| | LOC110945615 | Serine/threonine-protein phosphatase 4 catalytic subunit B. (310 aa) |
| | ENSAPOP00000030945 | SAE2 domain-containing protein. (74 aa) |
| | LOC110964368 | Uncharacterized protein. (559 aa) |
| | LOC110945936 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa) |
| | pole4 | Polymerase (DNA-directed), epsilon 4, accessory subunit. (128 aa) |
| | recql4 | RecQ helicase-like 4. (1281 aa) |
| | ENSAPOP00000030017 | Uncharacterized protein. (401 aa) |
| | rfc4 | Replication factor C (activator 1) 4. (357 aa) |
| | LOC110957885 | Protein phosphatase 4, regulatory subunit 2a. (411 aa) |
| | LOC110958398 | Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1. (532 aa) |
| | hus1 | Checkpoint protein; Belongs to the HUS1 family. (250 aa) |
| | LOC110946883 | CBFD_NFYB_HMF domain-containing protein. (116 aa) |
| | babam2 | BRISC and BRCA1 A complex member 2. (270 aa) |
| | atm | Non-specific serine/threonine protein kinase. (3026 aa) |
| | ENSAPOP00000027967 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (87 aa) |
| | babam1 | BRISC and BRCA1 A complex member 1. (379 aa) |
| | uba52 | Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa) |
| | LOC110947217 | Lys-63-specific deubiquitinase BRCC36. (262 aa) |
| | RCBTB1 | RCC1 and BTB domain containing protein 1. (531 aa) |
| | sirt7 | Sirtuin 7. (406 aa) |
| | ENSAPOP00000026301 | Uncharacterized protein. (145 aa) |
| | exo1 | Exonuclease 1. (756 aa) |
| | RNF169 | Ring finger protein 169. (580 aa) |
| | LOC110968155 | Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (318 aa) |
| | abl1 | Tyrosine-protein kinase. (1119 aa) |
| | LOC110966406 | Small ubiquitin-related modifier. (99 aa) |
| | mdc1 | Uncharacterized protein. (2156 aa) |
| | rad51ap1 | RAD51 associated protein 1. (320 aa) |
| | brca1 | Uncharacterized protein. (1388 aa) |
| | LOC110967609 | ANK_REP_REGION domain-containing protein. (603 aa) |
| | pias4 | Protein inhibitor of activated STAT, 4a. (507 aa) |
| | rhno1 | Si:ch73-352p4.5. (297 aa) |
| | ccna1 | Cyclin A1; Belongs to the cyclin family. (419 aa) |
| | SPIDR | Scaffold protein involved in DNA repair. (810 aa) |
| | ube2v2 | Ubiquitin-conjugating enzyme E2 variant 2. (145 aa) |
| | rfc2 | Replication factor C (activator 1) 2. (352 aa) |
| | LOC110954086 | Histone H2B; Belongs to the histone H2B family. (126 aa) |
| | ENSAPOP00000022517 | Reverse transcriptase domain-containing protein. (206 aa) |
| | slf1 | SMC5-SMC6 complex localization factor 1. (879 aa) |
| | ankrd11 | Ankyrin repeat domain 11. (2849 aa) |
| | topbp1 | DNA topoisomerase II binding protein 1. (1518 aa) |
| | rad52 | RAD52 homolog, DNA repair protein. (485 aa) |
| | polk | Polymerase (DNA directed) kappa. (884 aa) |
| | rpa2 | Replication protein A2. (294 aa) |
| | nbn | Nibrin. (854 aa) |
| | ENSAPOP00000020364 | Uncharacterized protein. (221 aa) |
| | ENSAPOP00000020269 | Uncharacterized protein; Belongs to the histone H2B family. (120 aa) |
| | ENSAPOP00000020171 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (120 aa) |
| | pold2 | Polymerase (DNA directed), delta 2, regulatory subunit. (472 aa) |
| | rps27a | Ribosomal protein S27a. (156 aa) |
| | pcna | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa) |
| | rad51d | RAD51 paralog D. (333 aa) |
| | dna2 | DNA replication helicase/nuclease 2. (997 aa) |
| | LOC110967845 | MUS81 structure-specific endonuclease subunit. (591 aa) |
| | ENSAPOP00000017332 | BRCA1/BRCA2-containing complex, subunit 3. (281 aa) |
| | ENSAPOP00000016753 | Nuclear receptor binding SET domain protein 2. (1158 aa) |
| | sumo2 | Small ubiquitin-related modifier. (95 aa) |
| | rpa3 | Replication protein A3. (122 aa) |
| | ENSAPOP00000015997 | annotation not available (120 aa) |
| | LOC110946478 | DNA polymerase delta subunit 4-like. (108 aa) |
| | ube2n | Ubiquitin-conjugating enzyme E2Nb; Belongs to the ubiquitin-conjugating enzyme family. (154 aa) |
| | pold3 | Polymerase (DNA-directed), delta 3, accessory subunit. (446 aa) |
| | ENSAPOP00000015596 | annotation not available (246 aa) |
| | ENSAPOP00000015519 | Uncharacterized protein. (53 aa) |
| | PPP4C | Serine/threonine-protein phosphatase. (310 aa) |
| | LOC110951404 | Histone H2B; Belongs to the histone H2B family. (116 aa) |
| | EME2 | ERCC4 domain-containing protein. (436 aa) |
| | ENSAPOP00000015249 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (132 aa) |
| | ENSAPOP00000015209 | Uncharacterized protein. (246 aa) |
| | blm | BLM RecQ like helicase. (1406 aa) |
| | LOC110966133 | Serine/threonine-protein phosphatase. (311 aa) |
| | eme1 | Essential meiotic structure-specific endonuclease 1. (524 aa) |
| | LOC110970504 | Histone H2A; Belongs to the histone H2A family. (138 aa) |
| | kat5 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (553 aa) |
| | ankrd12 | Ankyrin repeat domain 12. (1940 aa) |
| | tdrd3 | Tudor domain containing 3. (788 aa) |
| | rfc3 | Replication factor C (activator 1) 3. (356 aa) |
| | LOC110945681 | Histone H2B 1/2-like. (67 aa) |
| | LOC110945714 | DNA polymerase delta subunit 4-like. (108 aa) |
| | cdca7 | Cell division cycle associated 7a. (400 aa) |
| | LOC110946759 | Si:dkey-28b4.7. (108 aa) |
| | ENSAPOP00000012530 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (105 aa) |
| | rnf8 | E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] (481 aa) |
| | LOC110947992 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (152 aa) |
| | meiob | Methionine sulfoxide reductase B1b. (434 aa) |
| | ppp4r2 | Protein phosphatase 4, regulatory subunit 2b. (437 aa) |
| | ENSAPOP00000011452 | RAD50 homolog, double strand break repair protein. (551 aa) |
| | rad17 | RAD17 checkpoint clamp loader component. (637 aa) |
| | uimc1 | Uncharacterized protein. (979 aa) |
| | chek1 | Checkpoint kinase 1; Belongs to the protein kinase superfamily. (460 aa) |
| | pole2 | DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (536 aa) |
| | ENSAPOP00000010859 | Histone domain-containing protein; Belongs to the histone H2B family. (109 aa) |
| | rfc5 | Replication factor C (activator 1) 5. (339 aa) |
| | LOC110954465 | Small ubiquitin-related modifier. (123 aa) |
| | ENSAPOP00000010303 | Histone H2B; Belongs to the histone H2B family. (113 aa) |
| | LOC110946968 | MPN domain-containing protein. (262 aa) |
| | ENSAPOP00000010123 | Uncharacterized protein. (107 aa) |
| | xrcc3 | DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily. (343 aa) |
| | LOC110948070 | SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae). (1728 aa) |
| | LOC110963330 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (600 aa) |
| | ENSAPOP00000008964 | Reverse transcriptase domain-containing protein. (1132 aa) |
| | rmi1 | RMI1, RecQ mediated genome instability 1, homolog (S. cerevisiae). (713 aa) |
| | LOC110969388 | RAD50 homolog, double strand break repair protein. (545 aa) |
| | ENSAPOP00000008555 | Histone H2B; Belongs to the histone H2B family. (67 aa) |
| | atr | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2407 aa) |
| | pole | DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2101 aa) |
| | ENSAPOP00000007491 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (83 aa) |
| | LOC110970616 | ERCC4 domain-containing protein. (551 aa) |
| | tp53bp1 | Tumor protein p53 binding protein, 1. (1705 aa) |
| | LOC110972139 | Histone domain-containing protein; Belongs to the histone H2B family. (112 aa) |
| | rfc1 | Replication factor C subunit 1. (1183 aa) |
| | ENSAPOP00000005973 | Uncharacterized protein. (185 aa) |
| | ENSAPOP00000005929 | Uncharacterized protein. (157 aa) |
| | cdk2 | Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily. (298 aa) |
| | rad9a | Cell cycle checkpoint control protein; Belongs to the rad9 family. (395 aa) |
| | timeless | Timeless circadian clock. (1249 aa) |
| | LOC110964673 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (158 aa) |
| | polh | Polymerase (DNA directed), eta. (736 aa) |
| | xrcc2 | RECA_2 domain-containing protein. (290 aa) |
| | pole3 | Polymerase (DNA directed), epsilon 3 (p17 subunit). (147 aa) |
| | ENSAPOP00000003675 | Ubiquitin-like domain-containing protein. (84 aa) |
| | brca2 | BRCA2 DNA repair associated. (2779 aa) |
| | kxd1 | KxDL motif containing 1. (184 aa) |
| | exd2 | Exonuclease 3'-5' domain containing 2. (640 aa) |
| | SUMO3 | Small ubiquitin-related modifier. (94 aa) |
| | rmi2 | RecQ mediated genome instability 2. (144 aa) |
| | ccna2 | Cyclin A2; Belongs to the cyclin family. (436 aa) |
| | ENSAPOP00000001109 | BRISC and BRCA1 A complex member 2. (211 aa) |
| | tipin | TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (354 aa) |
| | ENSAPOP00000000534 | Uncharacterized protein. (166 aa) |
| | rnf168 | Uncharacterized protein. (303 aa) |
| | ENSAPOP00000000265 | Chromo_2 domain-containing protein. (549 aa) |
