(27 nodes) Main axon network (Oreochromis niloticus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	dag1	Dystroglycan 1. (903 aa)
	LOC100691500	Potassium voltage-gated channel, shaker-related subfamily, beta member 1 b. (420 aa)
	LOC100698156	Amino acid transporter. (563 aa)
	slc1a2	Amino acid transporter. (580 aa)
	KCNAB3	Potassium voltage-gated channel subfamily A regulatory beta subunit 3. (437 aa)
	scn1b	Ig-like domain-containing protein. (275 aa)
	KCNAB1	Potassium voltage-gated channel subfamily A member regulatory beta subunit 1. (423 aa)
	dagla	Diacylglycerol lipase, alpha. (1092 aa)
	NAV1	Neuron navigator 1. (2290 aa)
	LOC100709904	Voltage-gated potassium channel subunit beta-2. (396 aa)
	LOC100691202	Sodium channel, voltage-gated, type I, beta a. (223 aa)
	Mbp	Myelin basic protein b. (134 aa)
	LOC100707064	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (215 aa)
	ucn	Urotensin 1. (148 aa)
	cldn5	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (216 aa)
	Lg19h9orf72	Zgc:100846. (478 aa)
	LOC100699984	Peptidase S72 domain-containing protein. (909 aa)
	sirt2	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (382 aa)
	crhbp	Corticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family. (323 aa)
	LOC100698856	Par-3 family cell polarity regulator alpha, b. (1412 aa)
	I3KBN6_ORENI	Neuron navigator 1b. (1844 aa)
	LOC100704176	Corticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family. (322 aa)
	LOC100711823	Amino acid transporter. (668 aa)
	Cntn2	Contactin 2. (1052 aa)
	LOC100696040	Aldo_ket_red domain-containing protein. (399 aa)
	PARD3	Par-3 family cell polarity regulator. (1376 aa)
	LOC100712318	Hyaluronan and proteoglycan link protein 2. (357 aa)

Your Current Organism:

Oreochromis niloticus

NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC100691202	scn1b	ENSONIP00000042678	ENSONIP00000072547	Sodium channel, voltage-gated, type I, beta a.	Ig-like domain-containing protein.	0.906
LOC100698856	LOC100707064	ENSONIP00000018826	ENSONIP00000026611	Par-3 family cell polarity regulator alpha, b.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.650
LOC100698856	PARD3	ENSONIP00000018826	ENSONIP00000004615	Par-3 family cell polarity regulator alpha, b.	Par-3 family cell polarity regulator.	0.902
LOC100698856	cldn5	ENSONIP00000018826	ENSONIP00000025737	Par-3 family cell polarity regulator alpha, b.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.650
LOC100699984	dag1	ENSONIP00000021921	ENSONIP00000023354	Peptidase S72 domain-containing protein.	Dystroglycan 1.	0.902
LOC100704176	ucn	ENSONIP00000018178	ENSONIP00000026599	Corticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family.	Urotensin 1.	0.744
LOC100707064	LOC100698856	ENSONIP00000026611	ENSONIP00000018826	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Par-3 family cell polarity regulator alpha, b.	0.650
LOC100707064	PARD3	ENSONIP00000026611	ENSONIP00000004615	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Par-3 family cell polarity regulator.	0.650
LOC100707064	cldn5	ENSONIP00000026611	ENSONIP00000025737	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.655
PARD3	LOC100698856	ENSONIP00000004615	ENSONIP00000018826	Par-3 family cell polarity regulator.	Par-3 family cell polarity regulator alpha, b.	0.902
PARD3	LOC100707064	ENSONIP00000004615	ENSONIP00000026611	Par-3 family cell polarity regulator.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.650
PARD3	cldn5	ENSONIP00000004615	ENSONIP00000025737	Par-3 family cell polarity regulator.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.650
cldn5	LOC100698856	ENSONIP00000025737	ENSONIP00000018826	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Par-3 family cell polarity regulator alpha, b.	0.650
cldn5	LOC100707064	ENSONIP00000025737	ENSONIP00000026611	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.655
cldn5	PARD3	ENSONIP00000025737	ENSONIP00000004615	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Par-3 family cell polarity regulator.	0.650
crhbp	ucn	ENSONIP00000019441	ENSONIP00000026599	Corticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family.	Urotensin 1.	0.744
dag1	LOC100699984	ENSONIP00000023354	ENSONIP00000021921	Dystroglycan 1.	Peptidase S72 domain-containing protein.	0.902
scn1b	LOC100691202	ENSONIP00000072547	ENSONIP00000042678	Ig-like domain-containing protein.	Sodium channel, voltage-gated, type I, beta a.	0.906
ucn	LOC100704176	ENSONIP00000026599	ENSONIP00000018178	Urotensin 1.	Corticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family.	0.744
ucn	crhbp	ENSONIP00000026599	ENSONIP00000019441	Urotensin 1.	Corticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family.	0.744