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copb1 copb1 ncapd3 ncapd3 ncapd2 ncapd2 ap3b1 ap3b1 LOC100707472 LOC100707472 ap1b1 ap1b1 ap3d1 ap3d1 AP3B2 AP3B2 LOC100694377 LOC100694377 ap1g1 ap1g1 LOC100700052 LOC100700052 ap4b1 ap4b1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
copb1Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (953 aa)
ncapd3Condensin-2 complex subunit D3; Regulatory subunit of the condensin-2 complex, a complex which establishes mitotic chromosome architecture and is involved in physical rigidity of the chromatid axis. (1225 aa)
ncapd2Condensin complex subunit 1; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. (1401 aa)
ap3b1AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1176 aa)
LOC100707472AP complex subunit beta. (953 aa)
ap1b1AP complex subunit beta. (1001 aa)
ap3d1Adaptor related protein complex 3 subunit delta 1. (1167 aa)
AP3B2AP-3 complex subunit beta. (1230 aa)
LOC100694377AP-1 complex subunit gamma. (789 aa)
ap1g1AP-1 complex subunit gamma. (823 aa)
LOC100700052AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (965 aa)
ap4b1AP complex subunit beta; Belongs to the adaptor complexes large subunit family. (843 aa)
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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