STRINGSTRING
elovl6 elovl6 LOC100702823 LOC100702823 LOC100699909 LOC100699909 LOC100694706 LOC100694706 cbr4 cbr4 acadvl acadvl LOC100710535 LOC100710535 hacd1 hacd1 ELOVL6 ELOVL6 HACD3 HACD3 LOC100711736 LOC100711736 LOC100692024 LOC100692024 Echs1 Echs1 LOC100706973 LOC100706973 LOC100696941 LOC100696941 oxsm oxsm MCAT MCAT Acads Acads LOC100705521 LOC100705521 ppt1 ppt1 LOC100693325 LOC100693325 hsd17b4 hsd17b4 elovl7 elovl7 hsd17b12 hsd17b12 mecr mecr LOC100707217 LOC100707217 hadh hadh cpt2 cpt2 hsd17b8 hsd17b8 acat2 acat2 elovl5 elovl5 LOC100704930 LOC100704930 acsbg2 acsbg2 LOC100709135 LOC100709135 LOC100706142 LOC100706142 Fasn Fasn acaa2 acaa2 LOC100704158 LOC100704158 ENSONIP00000038765 ENSONIP00000038765 LOC100703825 LOC100703825 ACSF3 ACSF3 ehhadh ehhadh acsl3 acsl3 acat1 acat1 LOC100698402 LOC100698402 hacd2 hacd2 LOC100697613 LOC100697613 acox3 acox3 ELOVL1 ELOVL1 LOC100695278 LOC100695278 acadsb acadsb LOC100698696 LOC100698696 ppt2 ppt2 SCD SCD LOC100703423 LOC100703423 acsbg1 acsbg1 acadm acadm LOC100711328 LOC100711328 LOC100698825 LOC100698825
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
elovl6Elongation of very long chain fatty acids protein 6; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degre [...] (269 aa)
LOC100702823Acetyl-CoA carboxylase alpha. (2406 aa)
LOC100699909Trans-2,3-enoyl-CoA reductase a. (342 aa)
LOC100694706Zgc:66024. (338 aa)
cbr4Carbonyl reductase 4. (238 aa)
acadvlAcyl-CoA dehydrogenase very long chain. (659 aa)
LOC100710535Trans-2,3-enoyl-CoA reductase-like 2a. (311 aa)
hacd1Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (242 aa)
ELOVL6Elongation of very long chain fatty acids protein 6; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degre [...] (271 aa)
HACD3Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (380 aa)
LOC100711736Elongation of very long chain fatty acids protein 4; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that specifically elongates C24:0 and C26:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane [...] (345 aa)
LOC100692024Elongation of very long chain fatty acids protein. (269 aa)
Echs1Enoyl CoA hydratase, short chain, 1, mitochondrial; Belongs to the enoyl-CoA hydratase/isomerase family. (401 aa)
LOC100706973Elongation of very long chain fatty acids protein 1; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that [...] (314 aa)
LOC100696941Acyl-CoA synthetase long chain family member 3b. (724 aa)
oxsm3-oxoacyl-[acyl-carrier-protein] synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (474 aa)
MCATMalonyl CoA:ACP acyltransferase (mitochondrial). (400 aa)
AcadsAcyl-CoA dehydrogenase short chain. (495 aa)
LOC100705521Acyl-CoA synthetase long chain family member 2. (712 aa)
ppt1Palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis, neuronal 1, infantile). (303 aa)
LOC100693325Carnitine palmitoyltransferase 1Ab (liver); Belongs to the carnitine/choline acetyltransferase family. (804 aa)
hsd17b4Hydroxysteroid (17-beta) dehydrogenase 4. (730 aa)
elovl7Elongation of very long chain fatty acids protein 7; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:3(n-3) acyl-CoAs and C18:3(n-6)-CoAs. Also active toward C20:4-, C18:0-, C18:1-, C18:2- and C16:0-CoAs, and weakly toward C20:0-CoA. Little or no activity toward C22:0-, C24:0 [...] (294 aa)
hsd17b12Hydroxysteroid (17-beta) dehydrogenase 12a; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (327 aa)
mecrMitochondrial trans-2-enoyl-CoA reductase. (381 aa)
LOC100707217AMP-binding domain-containing protein. (745 aa)
hadhUncharacterized protein. (309 aa)
cpt2Carnitine palmitoyltransferase 2; Belongs to the carnitine/choline acetyltransferase family. (670 aa)
hsd17b8Hydroxysteroid (17-beta) dehydrogenase 8. (256 aa)
acat2Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. (402 aa)
elovl5Elongation of very long chain fatty acids protein 5; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA. May participate to the production of monounsaturated and of polyunsaturated VLCFAs of different chain lengths that are involv [...] (293 aa)
LOC100704930Carnitine palmitoyltransferase 1C; Belongs to the carnitine/choline acetyltransferase family. (790 aa)
acsbg2Acyl-CoA synthetase bubblegum family member 2. (766 aa)
LOC100709135Elongation of very long chain fatty acids protein. (264 aa)
LOC100706142AMP-binding domain-containing protein. (757 aa)
FasnCoiled-coil domain containing 57. (2541 aa)
acaa2Acetyl-CoA acyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. (404 aa)
LOC100704158Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha a. (779 aa)
ENSONIP00000038765Malonyl-CoA-acyl carrier protein transacylase, mitochondrial. (296 aa)
LOC100703825Hydroxysteroid (17-beta) dehydrogenase 12b; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (324 aa)
ACSF3Acyl-CoA synthetase family member 3. (613 aa)
ehhadhEnoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase; Belongs to the enoyl-CoA hydratase/isomerase family. (719 aa)
acsl3AMP-binding domain-containing protein. (731 aa)
acat1Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. (420 aa)
LOC100698402Carnitine palmitoyltransferase 1Cb; Belongs to the carnitine/choline acetyltransferase family. (810 aa)
hacd2Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (244 aa)
LOC100697613Elongation of very long chain fatty acids protein 6; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degre [...] (270 aa)
acox3Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (698 aa)
ELOVL1Elongation of very long chain fatty acids protein 1; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that [...] (372 aa)
LOC100695278Elongation of very long chain fatty acids protein 4; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that specifically elongates C24:0 and C26:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane [...] (360 aa)
acadsbAcyl-CoA dehydrogenase short/branched chain. (453 aa)
LOC100698696Acyl-CoA dehydrogenase long chain. (443 aa)
ppt2Lysosomal thioesterase PPT2 isoform X1. (324 aa)
SCDStearoyl-CoA desaturase; Belongs to the fatty acid desaturase type 1 family. (346 aa)
LOC100703423Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha b; Belongs to the enoyl-CoA hydratase/isomerase family. (763 aa)
acsbg1Acyl-CoA synthetase bubblegum family member 1. (726 aa)
acadmAcyl-CoA dehydrogenase medium chain. (436 aa)
LOC100711328Sterol carrier protein 2a; Belongs to the thiolase-like superfamily. Thiolase family. (560 aa)
LOC100698825Carnitine palmitoyltransferase 1B (muscle); Belongs to the carnitine/choline acetyltransferase family. (797 aa)
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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