(12 nodes) Macrophage activation network (Astatotilapia calliptera)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSACLP00000029872	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (497 aa)
	ifi35	Interferon-induced protein 35. (373 aa)
	LOC113032190	Chemokine (C-X-C motif) receptor 3, tandem duplicate 2; Belongs to the G-protein coupled receptor 1 family. (368 aa)
	tyrobp	Uncharacterized protein. (108 aa)
	LOC113026110	JunE proto-oncogene, AP-1 transcription factor subunit. (347 aa)
	LOC113019998	Phospholipase A(2). (153 aa)
	nmi	Uncharacterized protein. (417 aa)
	LOC113022202	C1q domain-containing protein. (293 aa)
	LOC113031642	Tumor necrosis factor b (TNF superfamily, member 2). (247 aa)
	ENSACLP00000018137	Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (261 aa)
	l3hypdh	Trans-L-3-hydroxyproline dehydratase. (354 aa)
	SUCNR1	Succinate receptor 1; Belongs to the G-protein coupled receptor 1 family. (485 aa)

Your Current Organism:

Astatotilapia calliptera

NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSACLP00000018137	LOC113031642	ENSACLP00000018137	ENSACLP00000015585	Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family.	Tumor necrosis factor b (TNF superfamily, member 2).	0.892
LOC113026110	LOC113031642	ENSACLP00000007182	ENSACLP00000015585	JunE proto-oncogene, AP-1 transcription factor subunit.	Tumor necrosis factor b (TNF superfamily, member 2).	0.893
LOC113031642	ENSACLP00000018137	ENSACLP00000015585	ENSACLP00000018137	Tumor necrosis factor b (TNF superfamily, member 2).	Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family.	0.892
LOC113031642	LOC113026110	ENSACLP00000015585	ENSACLP00000007182	Tumor necrosis factor b (TNF superfamily, member 2).	JunE proto-oncogene, AP-1 transcription factor subunit.	0.893
ifi35	nmi	ENSACLP00000033660	ENSACLP00000008765	Interferon-induced protein 35.	Uncharacterized protein.	0.971
nmi	ifi35	ENSACLP00000008765	ENSACLP00000033660	Uncharacterized protein.	Interferon-induced protein 35.	0.971