(44 nodes) Artery development network (Sparus aurata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC115579700	Mothers against decapentaplegic homolog 6-like. (506 aa)
	LOC115590260	Endothelin-1 receptor-like. (451 aa)
	amotl2	Angiomotin like 2. (708 aa)
	LOC115567020	Vascular endothelial growth factor A-A-like. (189 aa)
	hey2	Hes related family bHLH transcription factor with YRPW motif 2. (352 aa)
	hpgd	15-hydroxyprostaglandin dehydrogenase. (261 aa)
	edn1	Endothelin 1. (207 aa)
	ENSSAUP00010009010	annotation not available (1778 aa)
	hectd1	HECT domain E3 ubiquitin protein ligase 1. (2578 aa)
	LOC115588639	Bone morphogenetic protein receptor type-2-like. (1228 aa)
	nprl3	NPR3 like, GATOR1 complex subunit. (609 aa)
	ednra	Endothelin receptor type A. (442 aa)
	ANGPTL3	Angiopoietin like 3. (476 aa)
	LOC115597359	Apolipoprotein B-100-like. (4385 aa)
	LOC115582058	Homeobox protein Nkx-3.1-like. (195 aa)
	smad6	SMAD family member 6. (491 aa)
	prdm1	PR/SET domain 1. (857 aa)
	LOC115580567	Receptor for retinol uptake stra6-like. (677 aa)
	LOC115596134	Gap junction alpha-5 protein-like. (407 aa)
	ENSSAUP00010027735	Neurofibromin 1b. (2803 aa)
	ENSSAUP00010029099	PR domain containing 1b, with ZNF domain. (686 aa)
	arid2	AT-rich interaction domain 2. (1687 aa)
	smad7	SMAD family member 7. (376 aa)
	LOC115588250	Calcitonin gene-related peptide type 1 receptor. (477 aa)
	ENSSAUP00010000023	annotation not available (1068 aa)
	pum2	Pumilio RNA binding family member 2. (3270 aa)
	tab1	TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (512 aa)
	LOC115574656	Apolipoprotein B-100-like. (3783 aa)
	ENSSAUP00010034162	annotation not available (3768 aa)
	tcf21	Transcription factor 21. (168 aa)
	gja5	Gap junction protein alpha 5. (383 aa)
	LOC115573257	Angiomotin-like 2a. (701 aa)
	LOC115573625	PR domain zinc finger protein 1-like. (780 aa)
	SRF	Serum response factor. (614 aa)
	LOC115592856	Neurogenic locus notch homolog protein 1-like. (2469 aa)
	ENSSAUP00010050815	Dynactin 5. (140 aa)
	fkbp10	FKBP prolyl isomerase 10. (585 aa)
	LOC115571973	T-cell acute lymphocytic leukemia protein 1. (399 aa)
	angptl3	Angiopoietin like 3. (472 aa)
	ENSSAUP00010056964	FKBP prolyl isomerase 10b. (575 aa)
	notch1	Notch receptor 1. (2518 aa)
	ddit3	DNA damage inducible transcript 3. (312 aa)
	LOC115594799	15-hydroxyprostaglandin dehydrogenase [NAD(+)]-like. (318 aa)
	bmpr2	Bone morphogenetic protein receptor type 2. (1071 aa)

Your Current Organism:

Sparus aurata

NCBI taxonomy Id: 8175
Other names: Aurata aurata, S. aurata, Sparus auratus, gilthead bream, gilthead seabream, silver seabream

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSAUP00010009010	LOC115567020	ENSSAUP00010009010	ENSSAUP00010004402	annotation not available	Vascular endothelial growth factor A-A-like.	0.400
LOC115567020	ENSSAUP00010009010	ENSSAUP00010004402	ENSSAUP00010009010	Vascular endothelial growth factor A-A-like.	annotation not available	0.400
LOC115579700	LOC115588639	ENSSAUP00010002602	ENSSAUP00010012874	Mothers against decapentaplegic homolog 6-like.	Bone morphogenetic protein receptor type-2-like.	0.705
LOC115579700	LOC115592856	ENSSAUP00010002602	ENSSAUP00010045229	Mothers against decapentaplegic homolog 6-like.	Neurogenic locus notch homolog protein 1-like.	0.421
LOC115579700	bmpr2	ENSSAUP00010002602	ENSSAUP00010069097	Mothers against decapentaplegic homolog 6-like.	Bone morphogenetic protein receptor type 2.	0.705
LOC115579700	smad7	ENSSAUP00010002602	ENSSAUP00010031842	Mothers against decapentaplegic homolog 6-like.	SMAD family member 7.	0.814
LOC115579700	tab1	ENSSAUP00010002602	ENSSAUP00010033979	Mothers against decapentaplegic homolog 6-like.	TGF-beta activated kinase 1 (MAP3K7) binding protein 1.	0.471
LOC115588639	LOC115579700	ENSSAUP00010012874	ENSSAUP00010002602	Bone morphogenetic protein receptor type-2-like.	Mothers against decapentaplegic homolog 6-like.	0.705
LOC115588639	smad6	ENSSAUP00010012874	ENSSAUP00010026796	Bone morphogenetic protein receptor type-2-like.	SMAD family member 6.	0.705
LOC115588639	smad7	ENSSAUP00010012874	ENSSAUP00010031842	Bone morphogenetic protein receptor type-2-like.	SMAD family member 7.	0.705
LOC115590260	edn1	ENSSAUP00010003714	ENSSAUP00010008703	Endothelin-1 receptor-like.	Endothelin 1.	0.992
LOC115590260	ednra	ENSSAUP00010003714	ENSSAUP00010017524	Endothelin-1 receptor-like.	Endothelin receptor type A.	0.848
LOC115592856	LOC115579700	ENSSAUP00010045229	ENSSAUP00010002602	Neurogenic locus notch homolog protein 1-like.	Mothers against decapentaplegic homolog 6-like.	0.421
LOC115592856	hey2	ENSSAUP00010045229	ENSSAUP00010006440	Neurogenic locus notch homolog protein 1-like.	Hes related family bHLH transcription factor with YRPW motif 2.	0.569
bmpr2	LOC115579700	ENSSAUP00010069097	ENSSAUP00010002602	Bone morphogenetic protein receptor type 2.	Mothers against decapentaplegic homolog 6-like.	0.705
bmpr2	smad6	ENSSAUP00010069097	ENSSAUP00010026796	Bone morphogenetic protein receptor type 2.	SMAD family member 6.	0.705
bmpr2	smad7	ENSSAUP00010069097	ENSSAUP00010031842	Bone morphogenetic protein receptor type 2.	SMAD family member 7.	0.705
edn1	LOC115590260	ENSSAUP00010008703	ENSSAUP00010003714	Endothelin 1.	Endothelin-1 receptor-like.	0.992
edn1	ednra	ENSSAUP00010008703	ENSSAUP00010017524	Endothelin 1.	Endothelin receptor type A.	0.993
ednra	LOC115590260	ENSSAUP00010017524	ENSSAUP00010003714	Endothelin receptor type A.	Endothelin-1 receptor-like.	0.848