78 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Lrp5.L	Uncharacterized protein. (1517 aa)
	A0A1L8ENI4	Uncharacterized protein. (815 aa)
	Zeb2.S	Uncharacterized protein. (1246 aa)
	fzd5	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (569 aa)
	Axin1.S	Uncharacterized protein. (839 aa)
	A0A1L8EUY4	Uncharacterized protein. (818 aa)
	wnt6	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
	prkd1	Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (861 aa)
	Notch1.S	Uncharacterized protein. (2524 aa)
	notch1	Uncharacterized protein. (2521 aa)
	wnt11b	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
	prkd1-2	Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (861 aa)
	tnks2	Poly [ADP-ribose] polymerase. (1165 aa)
	Sfrp5.S	Uncharacterized protein. (315 aa)
	wnt4	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
	dkk1	Dickkopf_N domain-containing protein. (263 aa)
	wnt4-2	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (367 aa)
	axin2	Uncharacterized protein. (707 aa)
	Bcl2.S	BH4_2 domain-containing protein. (253 aa)
	wnt3a	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
	Shh.L	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (444 aa)
	Fzd8.L	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (582 aa)
	Zeb1.S	Uncharacterized protein. (919 aa)
	fzd1	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (559 aa)
	sfrp4	Uncharacterized protein. (353 aa)
	angpt1	Fibrinogen C-terminal domain-containing protein. (503 aa)
	Epcam.S	Thyroglobulin type-1 domain-containing protein. (314 aa)
	epas1	Uncharacterized protein. (859 aa)
	sox7	Uncharacterized protein. (363 aa)
	Epcam.L	Thyroglobulin type-1 domain-containing protein. (314 aa)
	Epas1.L	Uncharacterized protein. (862 aa)
	Foxa2.L	Fork-head domain-containing protein. (434 aa)
	sox7-2	Uncharacterized protein. (362 aa)
	Dkk3.S	Dickkopf_N domain-containing protein. (257 aa)
	A0A1L8GK22	Uncharacterized protein. (817 aa)
	cdh1	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (871 aa)
	cdh3	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (905 aa)
	Jun.L	BZIP domain-containing protein; Belongs to the bZIP family. (314 aa)
	sfrp1	Uncharacterized protein. (311 aa)
	wif1	Uncharacterized protein. (374 aa)
	Sfrp1.L	Uncharacterized protein. (311 aa)
	Gstp1.L	Uncharacterized protein; Belongs to the GST superfamily. (212 aa)
	epo	Uncharacterized protein. (181 aa)
	A0A1L8H5Q6	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (420 aa)
	Ppard.S	Uncharacterized protein. (336 aa)
	tnfsf11	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (290 aa)
	pdgfd	Uncharacterized protein. (389 aa)
	tmprss2	Uncharacterized protein; Belongs to the peptidase S1 family. (476 aa)
	Tnfsf11.L	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (290 aa)
	Mmp3.L	ZnMc domain-containing protein. (503 aa)
	wnt11	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
	jade1	Uncharacterized protein. (827 aa)
	lef1	HMG box domain-containing protein. (372 aa)
	dkk2	Dickkopf_N domain-containing protein. (255 aa)
	tnks	Poly [ADP-ribose] polymerase. (1298 aa)
	Jund.S	BZIP domain-containing protein. (300 aa)
	fzd10	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (580 aa)
	sfrp2	Uncharacterized protein. (295 aa)
	A0A1L8HUV5	Uncharacterized protein. (829 aa)
	jund	BZIP domain-containing protein. (300 aa)
	wnt6-2	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
	bmp4	Bone morphogenetic protein 4. (401 aa)
	wif1-2	Wnt inhibitory factor-1. (374 aa)
	fzd10a	Frizzled 10A; Belongs to the G-protein coupled receptor Fz/Smo family. (586 aa)
	xfz8	Frizzled-8; Belongs to the G-protein coupled receptor Fz/Smo family. (583 aa)
	wnt7b	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa)
	dkk1-2	Dickkopf homolog 1. (259 aa)
	axin2-2	MGC81576 protein. (707 aa)
	angpt1-2	MGC80788 protein. (504 aa)
	myc	Transcriptional regulator; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (420 aa)
	hif1a	Hif1a-prov protein. (802 aa)
	sfrp2-2	Sfrp2-prov protein. (298 aa)
	ccnd1	Ccnd1-prov protein; Belongs to the cyclin family. (291 aa)
	sfrp5	Secreted frizzled-related protein 5. (315 aa)
	lef1-2	Lymphoid enhancer factor XLEF-1. (372 aa)
	bmp4-2	Bone morphogenetic protein 4. (400 aa)
	dkk2-2	Dickkopf homolog 2. (255 aa)
	c-Jun	C-Jun protein; Belongs to the bZIP family. (312 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8ENI4	A0A1L8H5Q6	A0A1L8ENI4	A0A1L8H5Q6	Uncharacterized protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.998
A0A1L8ENI4	Dkk3.S	A0A1L8ENI4	A0A1L8GDZ7	Uncharacterized protein.	Dickkopf_N domain-containing protein.	0.527
A0A1L8ENI4	Fzd8.L	A0A1L8ENI4	A0A1L8FVD0	Uncharacterized protein.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.635
A0A1L8ENI4	Jun.L	A0A1L8ENI4	A0A1L8GLZ4	Uncharacterized protein.	BZIP domain-containing protein; Belongs to the bZIP family.	0.535
A0A1L8ENI4	Lrp5.L	A0A1L8ENI4	A0A1L8GJX4	Uncharacterized protein.	Uncharacterized protein.	0.928
A0A1L8ENI4	Notch1.S	A0A1L8ENI4	A0A1L8F124	Uncharacterized protein.	Uncharacterized protein.	0.558
A0A1L8ENI4	Sfrp1.L	A0A1L8ENI4	A0A1L8H1S5	Uncharacterized protein.	Uncharacterized protein.	0.753
A0A1L8ENI4	Sfrp5.S	A0A1L8ENI4	A0A1L8FEX3	Uncharacterized protein.	Uncharacterized protein.	0.543
A0A1L8ENI4	Shh.L	A0A1L8ENI4	A0A1L8FV87	Uncharacterized protein.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.668
A0A1L8ENI4	bmp4	A0A1L8ENI4	B7ZPR8	Uncharacterized protein.	Bone morphogenetic protein 4.	0.569
A0A1L8ENI4	bmp4-2	A0A1L8ENI4	Q91703	Uncharacterized protein.	Bone morphogenetic protein 4.	0.561
A0A1L8ENI4	c-Jun	A0A1L8ENI4	Q9PVZ1	Uncharacterized protein.	C-Jun protein; Belongs to the bZIP family.	0.535
A0A1L8ENI4	ccnd1	A0A1L8ENI4	Q8AVQ4	Uncharacterized protein.	Ccnd1-prov protein; Belongs to the cyclin family.	0.853
A0A1L8ENI4	cdh1	A0A1L8ENI4	A0A1L8GKV4	Uncharacterized protein.	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	0.562
A0A1L8ENI4	cdh3	A0A1L8ENI4	A0A1L8GKW6	Uncharacterized protein.	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	0.562
A0A1L8ENI4	dkk1	A0A1L8ENI4	A0A1L8FIS6	Uncharacterized protein.	Dickkopf_N domain-containing protein.	0.899
A0A1L8ENI4	dkk1-2	A0A1L8ENI4	O57464	Uncharacterized protein.	Dickkopf homolog 1.	0.900
A0A1L8ENI4	dkk2	A0A1L8ENI4	A0A1L8HM80	Uncharacterized protein.	Dickkopf_N domain-containing protein.	0.665
A0A1L8ENI4	dkk2-2	A0A1L8ENI4	Q9DDA4	Uncharacterized protein.	Dickkopf homolog 2.	0.666
A0A1L8ENI4	fzd1	A0A1L8ENI4	A0A1L8FVQ7	Uncharacterized protein.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.677