(25 nodes) AAA ATPase, AAA+ lid domain network (Alligator mississippiensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ATAD1	ATPase family AAA domain-containing protein 1; Belongs to the AAA ATPase family. (409 aa)
	PSMC3	26S protease regulatory subunit 6A; Belongs to the AAA ATPase family. (404 aa)
	SPAST	Spastin; Belongs to the AAA ATPase family. (485 aa)
	PEX1	Peroxisome biogenesis factor 1 isoform A. (1279 aa)
	KATNAL1	Katanin p60 ATPase-containing subunit A-like 1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily. A-like 1 sub-subfamily. (565 aa)
	KATNAL2	Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays. (542 aa)
	PSMC6	26S protease regulatory subunit 10B; Belongs to the AAA ATPase family. (403 aa)
	SPATA5	Spermatogenesis-associated protein 5. (871 aa)
	ATAD2B-2	Bromo domain-containing protein. (1418 aa)
	ATAD2B	ATPase family AAA domain-containing protein 2B. (1982 aa)
	NSF	Vesicle-fusing ATPase. (742 aa)
	PSMC5	Proteasome (Prosome, macropain) 26S subunit, ATPase, 5; Belongs to the AAA ATPase family. (411 aa)
	AFG3L2	AFG3-like protein 2 isoform B. (808 aa)
	VPS4B-2	Uncharacterized protein; Belongs to the AAA ATPase family. (463 aa)
	PSMC4	26S protease regulatory subunit 6B; Belongs to the AAA ATPase family. (418 aa)
	KATNA1	Katanin p60 ATPase-containing subunit A1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. (532 aa)
	VPS4B	Vacuolar protein sorting-associated protein 4B; Belongs to the AAA ATPase family. (463 aa)
	PSMC2	26S protease regulatory subunit 7; Belongs to the AAA ATPase family. (433 aa)
	VCP	Uncharacterized protein; Belongs to the AAA ATPase family. (880 aa)
	SPATA5L1	Spermatogenesis-associated protein 5-like protein 1. (763 aa)
	FIGNL1	Fidgetin-like protein 1. (1085 aa)
	NVL	Nuclear valosin-containing protein-like. (853 aa)
	SPG7	60S ribosomal protein L13; Belongs to the eukaryotic ribosomal protein eL13 family. (1069 aa)
	PSMC1	26S protease regulatory subunit 4; Belongs to the AAA ATPase family. (440 aa)
	YME1L1	ATP-dependent zinc metalloprotease YME1L1 isoform A. (724 aa)

Your Current Organism:

Alligator mississippiensis

NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AFG3L2	SPG7	A0A151NF88	A0A151P4L2	AFG3-like protein 2 isoform B.	60S ribosomal protein L13; Belongs to the eukaryotic ribosomal protein eL13 family.	0.781
AFG3L2	YME1L1	A0A151NF88	A0A151PCQ1	AFG3-like protein 2 isoform B.	ATP-dependent zinc metalloprotease YME1L1 isoform A.	0.423
ATAD2B	PSMC3	A0A151MXR5	A0A151MB32	ATPase family AAA domain-containing protein 2B.	26S protease regulatory subunit 6A; Belongs to the AAA ATPase family.	0.610
ATAD2B	PSMC4	A0A151MXR5	A0A151NHC2	ATPase family AAA domain-containing protein 2B.	26S protease regulatory subunit 6B; Belongs to the AAA ATPase family.	0.610
ATAD2B	PSMC6	A0A151MXR5	A0A151PDY8	ATPase family AAA domain-containing protein 2B.	26S protease regulatory subunit 10B; Belongs to the AAA ATPase family.	0.610
ATAD2B-2	PSMC3	A0A151PIR4	A0A151MB32	Bromo domain-containing protein.	26S protease regulatory subunit 6A; Belongs to the AAA ATPase family.	0.610
ATAD2B-2	PSMC4	A0A151PIR4	A0A151NHC2	Bromo domain-containing protein.	26S protease regulatory subunit 6B; Belongs to the AAA ATPase family.	0.610
ATAD2B-2	PSMC6	A0A151PIR4	A0A151PDY8	Bromo domain-containing protein.	26S protease regulatory subunit 10B; Belongs to the AAA ATPase family.	0.610
FIGNL1	VPS4B	A0A151P135	A0A151NNR7	Fidgetin-like protein 1.	Vacuolar protein sorting-associated protein 4B; Belongs to the AAA ATPase family.	0.445
FIGNL1	VPS4B-2	A0A151P135	A0A151NFE7	Fidgetin-like protein 1.	Uncharacterized protein; Belongs to the AAA ATPase family.	0.445
KATNA1	PSMC3	A0A151NLL3	A0A151MB32	Katanin p60 ATPase-containing subunit A1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.	26S protease regulatory subunit 6A; Belongs to the AAA ATPase family.	0.664
KATNA1	PSMC4	A0A151NLL3	A0A151NHC2	Katanin p60 ATPase-containing subunit A1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.	26S protease regulatory subunit 6B; Belongs to the AAA ATPase family.	0.656
KATNA1	PSMC6	A0A151NLL3	A0A151PDY8	Katanin p60 ATPase-containing subunit A1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.	26S protease regulatory subunit 10B; Belongs to the AAA ATPase family.	0.664
KATNAL1	PSMC3	A0A151MS91	A0A151MB32	Katanin p60 ATPase-containing subunit A-like 1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily. A-like 1 sub-subfamily.	26S protease regulatory subunit 6A; Belongs to the AAA ATPase family.	0.667
KATNAL1	PSMC4	A0A151MS91	A0A151NHC2	Katanin p60 ATPase-containing subunit A-like 1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily. A-like 1 sub-subfamily.	26S protease regulatory subunit 6B; Belongs to the AAA ATPase family.	0.659
KATNAL1	PSMC6	A0A151MS91	A0A151PDY8	Katanin p60 ATPase-containing subunit A-like 1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily. A-like 1 sub-subfamily.	26S protease regulatory subunit 10B; Belongs to the AAA ATPase family.	0.667
KATNAL2	PSMC3	A0A151MWJ4	A0A151MB32	Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.	26S protease regulatory subunit 6A; Belongs to the AAA ATPase family.	0.902
KATNAL2	PSMC4	A0A151MWJ4	A0A151NHC2	Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.	26S protease regulatory subunit 6B; Belongs to the AAA ATPase family.	0.901
KATNAL2	PSMC6	A0A151MWJ4	A0A151PDY8	Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.	26S protease regulatory subunit 10B; Belongs to the AAA ATPase family.	0.901
KATNAL2	VPS4B	A0A151MWJ4	A0A151NNR7	Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.	Vacuolar protein sorting-associated protein 4B; Belongs to the AAA ATPase family.	0.464