STRINGSTRING
TANK TANK PTPN4 PTPN4 PELI1 PELI1 TONSL TONSL UNC93A UNC93A RPS6KA2 RPS6KA2 MAP2K7 MAP2K7 DUSP7 DUSP7 Y1Q_0022506 Y1Q_0022506 Y1Q_0017347 Y1Q_0017347 Y1Q_0020396 Y1Q_0020396 PPP2CB PPP2CB Y1Q_0018841 Y1Q_0018841 Y1Q_0018842 Y1Q_0018842 Y1Q_0006103 Y1Q_0006103 MAP2K6 MAP2K6 MAP2K3 MAP2K3 Y1Q_0008175 Y1Q_0008175 IRF3 IRF3 TLR7-1 TLR7-1 ELK1 ELK1 CD180-1 CD180-1 MAP3K1 MAP3K1 PIK3C3 PIK3C3 CTSS CTSS Y1Q_0000003 Y1Q_0000003 Y1Q_0000005 Y1Q_0000005 MAPK15 MAPK15 Y1Q_0013910 Y1Q_0013910 MAP3K7 MAP3K7 SFTPD-1 SFTPD-1 LL LL MBL2 MBL2 Y1Q_0005244 Y1Q_0005244 Y1Q_0008580 Y1Q_0008580 ATF1 ATF1 Y1Q_0021221 Y1Q_0021221 N4BP1 N4BP1 CARD8-2 CARD8-2 NOD1 NOD1 NKIRAS1 NKIRAS1 NLRC5 NLRC5 CREB5 CREB5 DFNA5 DFNA5 IKBKG IKBKG Y1Q_0013899 Y1Q_0013899 FNBP4 FNBP4 LY96 LY96 UNC93B1 UNC93B1 RIPK3L RIPK3L FOS FOS Y1Q_0020759 Y1Q_0020759 LRRC74A LRRC74A MAPK8 MAPK8 IRAK2 IRAK2 RBSN RBSN Y1Q_0020301 Y1Q_0020301 BPIFCL BPIFCL PELI1-2 PELI1-2 RPS27A RPS27A TLR4 TLR4 MAPKAPK3-2 MAPKAPK3-2 APP APP CNPY3 CNPY3 CNPY4 CNPY4 PPP2R1A PPP2R1A HPS5L HPS5L TRAF6 TRAF6 IKBKE IKBKE MAPKAPK3 MAPKAPK3 CTSL CTSL LRRC45 LRRC45 MAPK9 MAPK9 PPP2CA PPP2CA TLR22 TLR22 CTSK CTSK Y1Q_0022090 Y1Q_0022090 NKIRAS2 NKIRAS2 DUSP3 DUSP3 FGG FGG TLR3 TLR3 LGMN LGMN RPS6KA6 RPS6KA6 PPP4R4 PPP4R4 TRAF3 TRAF3 MAP2K4 MAP2K4 Y1Q_0013419 Y1Q_0013419 BIRC2 BIRC2 Y1Q_0010996 Y1Q_0010996 BPI BPI Y1Q_0012030 Y1Q_0012030 GSDMA GSDMA TRAF5 TRAF5 FOSL2 FOSL2 Y1Q_0013534 Y1Q_0013534 PIK3R4 PIK3R4 Y1Q_0013331 Y1Q_0013331 VWC2 VWC2 UBE2D1 UBE2D1 PPP4R1 PPP4R1 UBE2V1 UBE2V1 TMEM189 TMEM189 BIRC7-1 BIRC7-1 ATF7 ATF7 Y1Q_0006366 Y1Q_0006366 NLRP3 NLRP3 Y1Q_0006330 Y1Q_0006330 Y1Q_0006368 Y1Q_0006368 TLR21 TLR21 CTSB CTSB SARM1 SARM1 TONSLL TONSLL TAB3 TAB3 KXD1 KXD1 Y1Q_0020451 Y1Q_0020451 TLR2A TLR2A RPS6KA4 RPS6KA4 SCARB1 SCARB1 PTPN11 PTPN11 MAPK1 MAPK1 UBE2D2 UBE2D2 CD14 CD14 CD36 CD36 CCDC71L-1 CCDC71L-1 Y1Q_0019536 Y1Q_0019536 NFKB1 NFKB1 TAB2 TAB2 NFKBIA NFKBIA LRRC14 LRRC14 Y1Q_0020858 Y1Q_0020858 VTG1 VTG1 BPIFCB BPIFCB USP18 USP18 TAB1 TAB1 Y1Q_0024190 Y1Q_0024190 BPIFC BPIFC Y1Q_0008090 Y1Q_0008090 TIRAP TIRAP NLRX1 NLRX1 RIPK1 RIPK1 LY86 LY86 PPP4R1-2 PPP4R1-2 USP14 USP14 Y1Q_0004547 Y1Q_0004547 IRAK1 IRAK1 Y1Q_0020171 Y1Q_0020171 Y1Q_0020172 Y1Q_0020172 Y1Q_0020170 Y1Q_0020170 IKBKB-2 IKBKB-2 LRRC34 LRRC34 LRRC31 LRRC31 TLR5 TLR5 CREB1 CREB1 VWC2L VWC2L MAPK14 MAPK14 VRK3-1 VRK3-1 c-jun c-jun S100A9 S100A9 APOB APOB NFKBIB NFKBIB S100A1 S100A1 NAIP NAIP Y1Q_0004030 Y1Q_0004030 IKBKB IKBKB RIPK3 RIPK3 JUND JUND KHNYN KHNYN RIPK2 RIPK2 NFKB2 NFKB2 MAPK7 MAPK7 MAPK11 MAPK11 TBK1 TBK1 LRRC71 LRRC71 Y1Q_0017705 Y1Q_0017705 EEA1 EEA1 DUSP6 DUSP6 UBE2N UBE2N IKBIP IKBIP Y1Q_0011504 Y1Q_0011504 ATF2 ATF2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TANKTRAF family member-associated NF-kappa-B activator. (472 aa)
PTPN4Tyrosine-protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily. (953 aa)
PELI1E3 ubiquitin-ligase pellino-like protein 1. (397 aa)
TONSLTonsoku-like protein. (412 aa)
UNC93AUnc-93-like protein A isoform A. (886 aa)
RPS6KA2Ribosomal protein S6 kinase. (733 aa)
MAP2K7Dual specificity mitogen-activated protein kinase kinase 7 isoform C. (488 aa)
DUSP7Dual specificity protein phosphatase 7. (289 aa)
Y1Q_0022506Uncharacterized protein. (167 aa)
Y1Q_0017347NACHT, LRR and PYD domains-containing protein 3-like. (334 aa)
Y1Q_0020396Uncharacterized protein. (1078 aa)
PPP2CBSerine/threonine-protein phosphatase. (309 aa)
Y1Q_0018841Ig-like domain-containing protein. (665 aa)
Y1Q_0018842Uncharacterized protein. (192 aa)
Y1Q_0006103Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (594 aa)
MAP2K6Dual specificity mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (348 aa)
MAP2K3Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (337 aa)
Y1Q_0008175Vitellogenin-like. (3859 aa)
IRF3Interferon regulatory factor 3 isoform B. (462 aa)
TLR7-1Toll-like receptor 7 isoform B. (505 aa)
ELK1ETS domain-containing protein Elk-1. (396 aa)
CD180-1CD180 antigen isoform B. (378 aa)
MAP3K1Mitogen-activated protein kinase kinase kinase 1. (1175 aa)
PIK3C3Phosphatidylinositol 3-kinase catalytic subunit type 3. (886 aa)
CTSSCathepsin S; Belongs to the peptidase C1 family. (168 aa)
Y1Q_0000003TIR domain-containing protein. (145 aa)
Y1Q_0000005TIR domain-containing protein. (222 aa)
MAPK15Mitogen-activated protein kinase. (807 aa)
Y1Q_0013910Uncharacterized protein. (179 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7 isoform A. (610 aa)
SFTPD-1Pulmonary surfactant-associated protein D isoform B. (379 aa)
LLLung lectin. (372 aa)
MBL2Pulmonary surfactant-associated protein D. (234 aa)
Y1Q_0005244Pulmonary surfactant-associated protein D-like. (367 aa)
Y1Q_0008580Uncharacterized protein. (441 aa)
ATF1Cyclic AMP-dependent transcription factor ATF-1. (330 aa)
Y1Q_0021221TMEM189_B_dmain domain-containing protein. (76 aa)
N4BP1NEDD4-binding protein 1. (938 aa)
CARD8-2Caspase recruitment domain-containing protein 8. (317 aa)
NOD1Nucleotide-binding oligomerization domain-containing protein 1. (951 aa)
NKIRAS1NF-kappa-B inhibitor-interacting Ras-like protein 1. (192 aa)
NLRC5Protein NLRC5 isoform B. (1891 aa)
CREB5Cyclic AMP-responsive element-binding protein 5. (552 aa)
DFNA5Non-syndromic hearing impairment protein 5. (486 aa)
IKBKGNF-kappa-B essential modulator. (542 aa)
Y1Q_0013899Uncharacterized protein. (103 aa)
FNBP4Formin-binding protein 4 isoform B. (904 aa)
LY96Lymphocyte antigen 96. (131 aa)
UNC93B1Unc-93-like protein B1. (580 aa)
RIPK3LReceptor-interacting serine/threonine-protein kinase 2. (564 aa)
FOSProto-oncogene c-Fos isoform A. (530 aa)
Y1Q_0020759Uncharacterized protein. (171 aa)
LRRC74ALeucine-rich repeat-containing protein 74A isoform A. (478 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
IRAK2Interleukin-1 receptor-associated kinase-like 2. (732 aa)
RBSNRabenosyn-5. (783 aa)
Y1Q_0020301Bactericidal permeability-increasing protein. (472 aa)
BPIFCLLipopolysaccharide-binding protein. (661 aa)
PELI1-2Uncharacterized protein. (418 aa)
RPS27AUbiquitin-40S ribosomal protein S27a. (156 aa)
TLR4Toll-like receptor 4; Belongs to the Toll-like receptor family. (843 aa)
MAPKAPK3-2Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (387 aa)
APPBPTI/Kunitz inhibitor domain-containing protein. (743 aa)
CNPY3Canopy-like protein 3. (270 aa)
CNPY4Canopy-like protein 4 isoform B. (223 aa)
PPP2R1ASerine/threonine-protein phosphatase 2A regulatory subunit A alpha isoform. (643 aa)
HPS5LSerum amyloid A protein; Major acute phase reactant. Apolipoprotein of the HDL complex. (126 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (576 aa)
IKBKEUncharacterized protein. (1096 aa)
MAPKAPK3MAP kinase-activated protein kinase 3; Belongs to the protein kinase superfamily. (354 aa)
CTSLCathepsin L1; Belongs to the peptidase C1 family. (317 aa)
LRRC45Leucine-rich repeat-containing protein 45. (777 aa)
MAPK9Mitogen-activated protein kinase. (430 aa)
PPP2CASerine/threonine-protein phosphatase; Belongs to the SKP1 family. (474 aa)
TLR22Toll-like receptor 22 isoform A; Belongs to the Toll-like receptor family. (495 aa)
CTSKCathepsin K isoform B; Belongs to the peptidase C1 family. (388 aa)
Y1Q_0022090Ig-like domain-containing protein. (187 aa)
NKIRAS2NF-kappa-B inhibitor-interacting Ras-like protein 2. (191 aa)
DUSP3Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (184 aa)
FGGFibrinogen gamma chain. (431 aa)
TLR3Toll-like receptor 3; Belongs to the Toll-like receptor family. (948 aa)
LGMNLegumain. (470 aa)
RPS6KA6Ribosomal protein S6 kinase. (820 aa)
PPP4R4Serine/threonine-protein phosphatase 4 regulatory subunit 4 isoform A. (864 aa)
TRAF3TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (553 aa)
MAP2K4Dual specificity mitogen-activated protein kinase kinase 4 isoform A; Belongs to the protein kinase superfamily. (394 aa)
Y1Q_0013419Uncharacterized protein. (77 aa)
BIRC2Inhibitor of apoptosis protein. (493 aa)
Y1Q_0010996Toll-like receptor 13. (908 aa)
BPIBactericidal permeability-increasing protein. (464 aa)
Y1Q_0012030Gasdermin-A2-like. (524 aa)
GSDMAGasdermin-A. (671 aa)
TRAF5TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (588 aa)
FOSL2Fos-related antigen 2. (253 aa)
Y1Q_0013534NACHT, LRR and PYD domains-containing protein 3-like. (739 aa)
PIK3R4Phosphoinositide 3-kinase regulatory subunit 4. (1397 aa)
Y1Q_0013331Protein S100; Belongs to the S-100 family. (100 aa)
VWC2Brorin. (265 aa)
UBE2D1Ubiquitin-conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (197 aa)
PPP4R1Serine/threonine-protein phosphatase 4 regulatory subunit 1. (956 aa)
UBE2V1UBIQUITIN_CONJUGAT_2 domain-containing protein. (97 aa)
TMEM189Transmembrane protein 189. (271 aa)
BIRC7-1Baculoviral IAP repeat-containing protein 7 isoform A. (309 aa)
ATF7Cyclic AMP-dependent transcription factor ATF-7. (482 aa)
Y1Q_0006366Pyrin domain-containing protein. (469 aa)
NLRP3NACHT, LRR and PYD domains-containing protein 12. (901 aa)
Y1Q_0006330Synaptotagmin-2-like. (234 aa)
Y1Q_0006368Ribonuclease inhibitor-like. (770 aa)
TLR21Toll-like receptor 21 isoform A. (964 aa)
CTSBCathepsin B; Belongs to the peptidase C1 family. (400 aa)
SARM1Sterile alpha and TIR motif-containing protein 1. (716 aa)
TONSLLTonsoku-like protein. (924 aa)
TAB3TGF-beta-activated kinase 1 and MAP3K7-binding protein 3. (368 aa)
KXD1KxDL motif-containing protein 1. (293 aa)
Y1Q_0020451Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (281 aa)
TLR2AToll-like receptor 2 type-1; Belongs to the Toll-like receptor family. (801 aa)
RPS6KA4Non-specific serine/threonine protein kinase. (887 aa)
SCARB1Scavenger receptor class B member 1 isoform A. (959 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (608 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (410 aa)
UBE2D2Ubiquitin-conjugating enzyme E2 D2; Belongs to the ubiquitin-conjugating enzyme family. (171 aa)
CD14Monocyte differentiation antigen CD14. (461 aa)
CD36Platelet glycoprotein 4; Belongs to the CD36 family. (461 aa)
CCDC71L-1Coiled-coil domain-containing protein 71L isoform B. (79 aa)
Y1Q_0019536Mitogen-activated protein kinase. (505 aa)
NFKB1Nuclear factor NF-kappa-B p105 subunit isoform B. (1031 aa)
TAB2TGF-beta-activated kinase 1 and MAP3K7-binding protein 2. (276 aa)
NFKBIANF-kappa-B inhibitor alpha. (299 aa)
LRRC14Leucine-rich repeat-containing protein 14. (511 aa)
Y1Q_0020858Vitellogenin-1-like. (2014 aa)
VTG1Vitellogenin-1. (1746 aa)
BPIFCBBPI fold-containing family C protein isoform B. (482 aa)
USP18Ubl carboxyl-terminal hydrolase 18; Belongs to the peptidase C19 family. (359 aa)
TAB1TGF-beta-activated kinase 1 and MAP3K7-binding protein 1. (502 aa)
Y1Q_0024190HATPase_c domain-containing protein. (755 aa)
BPIFCBPI fold-containing family C protein. (477 aa)
Y1Q_0008090LisH domain-containing protein. (1143 aa)
TIRAPToll/interleukin-1 receptor domain-containing adapter protein. (230 aa)
NLRX1NLR family member X1. (818 aa)
RIPK1Receptor-interacting serine/threonine-protein kinase 1. (699 aa)
LY86Lymphocyte antigen 86. (161 aa)
PPP4R1-2WRNPLPNID domain-containing protein. (952 aa)
USP14Ubiquitin carboxyl-terminal hydrolase. (492 aa)
Y1Q_0004547Uncharacterized protein; Belongs to the peptidase C1 family. (309 aa)
IRAK1Interleukin-1 receptor-associated kinase 1. (918 aa)
Y1Q_0020171Uncharacterized protein. (219 aa)
Y1Q_0020172NACHT, LRR and PYD domains-containing protein 12-like. (484 aa)
Y1Q_0020170Pyrin domain-containing protein. (269 aa)
IKBKB-2Uncharacterized protein. (757 aa)
LRRC34Leucine-rich repeat-containing protein 34. (417 aa)
LRRC31Leucine-rich repeat-containing protein 31. (587 aa)
TLR5Toll-like receptor 5. (443 aa)
CREB1Cyclic AMP-responsive element-binding protein 1. (327 aa)
VWC2LVon Willebrand factor C domain-containing protein 2-like. (222 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
VRK3-1Inactive serine/threonine-protein kinase VRK3 isoform A. (407 aa)
c-junTranscription factor AP-1; Belongs to the bZIP family. (320 aa)
S100A9Protein S100; Belongs to the S-100 family. (116 aa)
APOBApolipoprotein B-100. (4482 aa)
NFKBIBNF-kappa-B inhibitor beta. (109 aa)
S100A1Protein S100; Belongs to the S-100 family. (127 aa)
NAIPBaculoviral IAP repeat-containing protein 1 isoform A. (878 aa)
Y1Q_0004030Uncharacterized protein. (147 aa)
IKBKBInhibitor of nuclear factor kappa-B kinase subunit beta. (730 aa)
RIPK3Receptor-interacting serine/threonine-protein kinase 3. (508 aa)
JUNDBZIP domain-containing protein. (87 aa)
KHNYNProtein KHNYN. (890 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2. (561 aa)
NFKB2Uncharacterized protein. (937 aa)
MAPK7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (675 aa)
MAPK11Mitogen-activated protein kinase. (361 aa)
TBK1Serine/threonine-protein kinase TBK1. (677 aa)
LRRC71Leucine-rich repeat-containing protein 71 isoform B. (526 aa)
Y1Q_0017705TBD domain-containing protein. (264 aa)
EEA1Early endosome antigen 1. (1428 aa)
DUSP6Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (382 aa)
UBE2NUbiquitin-conjugating enzyme E2 N. (112 aa)
IKBIPInhibitor of nuclear factor kappa-B kinase-interacting protein. (334 aa)
Y1Q_0011504Uncharacterized protein. (742 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2. (458 aa)
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
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