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guaA guaA trpS trpS shn_00720 shn_00720 shn_01330 shn_01330 shn_02875 shn_02875 shn_02880 shn_02880 shn_03640 shn_03640 ileS ileS cysD cysD cysH cysH cysS cysS valS valS argS argS shn_08515 shn_08515 ttcA ttcA coaD coaD metG metG tyrS tyrS nadE nadE panC panC mnmA mnmA gltX gltX shn_17805 shn_17805 shn_17835 shn_17835 argG argG nadD nadD leuS leuS shn_20395 shn_20395
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
guaAGlutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. (520 aa)
trpStryptophan--tRNA ligase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. (355 aa)
shn_00720Universal stress protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (146 aa)
shn_01330Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (263 aa)
shn_02875Electron transfer flavoprotein subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. (249 aa)
shn_02880Electron transfer flavoprotein subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. (309 aa)
shn_03640Riboflavin biosynthesis protein RibF; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribF family. (326 aa)
ileSisoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). (963 aa)
cysDSulfate adenylyltransferase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (317 aa)
cysHPhosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily. (249 aa)
cysScysteine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. (477 aa)
valSvaline--tRNA ligase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (975 aa)
argSarginine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (586 aa)
shn_08515Serine/threonine protein kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (471 aa)
ttcAtRNA 2-thiocytidine(32) synthetase TtcA; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system. (289 aa)
coaDPantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (164 aa)
metGmethionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily. (516 aa)
tyrStyrosine--tRNA ligase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. (417 aa)
nadENAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (559 aa)
panCPantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (289 aa)
mnmAtRNA 2-thiouridine(34) synthase MnmA; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (398 aa)
gltXglutamate--tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (489 aa)
shn_17805Electron transfer flavoprotein subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. (249 aa)
shn_17835tRNA glutamyl-Q synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. (302 aa)
argGArgininosuccinate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (407 aa)
nadDNicotinic acid mononucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (202 aa)
leuSleucine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. (876 aa)
shn_20395Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (294 aa)
Your Current Organism:
Shinella sp. HZN7
NCBI taxonomy Id: 879274
Other names: S. sp. HZN7
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