STRINGSTRING
Cabys_115 Cabys_115 APF17904.1 APF17904.1 APF17907.1 APF17907.1 deoB deoB pfp pfp pfkA pfkA APF18095.1 APF18095.1 APF18121.1 APF18121.1 APF18152.1 APF18152.1 APF18155.1 APF18155.1 APF18301.1 APF18301.1 Cabys_156 Cabys_156 APF18309.1 APF18309.1 tal tal tal-2 tal-2 APF18336.1 APF18336.1 APF18412.1 APF18412.1 APF18440.1 APF18440.1 APF18452.1 APF18452.1 APF18453.1 APF18453.1 fumC fumC Cabys_172 Cabys_172 Cabys_173 Cabys_173 APF18488.1 APF18488.1 APF18489.1 APF18489.1 APF18526.1 APF18526.1 fba fba APF18557.1 APF18557.1 APF18558.1 APF18558.1 APF18636.1 APF18636.1 APF18640.1 APF18640.1 APF18643.1 APF18643.1 APF18660.1 APF18660.1 APF18661.1 APF18661.1 gcvPA gcvPA gcvPB gcvPB pdxS pdxS APF18683.1 APF18683.1 glmS glmS Cabys_20 Cabys_20 APF18800.1 APF18800.1 APF18802.1 APF18802.1 APF18805.1 APF18805.1 APF18831.1 APF18831.1 gcvH gcvH Cabys_22 Cabys_22 APF18996.1 APF18996.1 APF19000.1 APF19000.1 APF19022.1 APF19022.1 APF19062.1 APF19062.1 APF19135.1 APF19135.1 APF19136.1 APF19136.1 APF19138.1 APF19138.1 APF19152.1 APF19152.1 APF19170.1 APF19170.1 fbp fbp gcvT gcvT APF19334.1 APF19334.1 APF19335.1 APF19335.1 Cabys_262 Cabys_262 APF19382.1 APF19382.1 pckA pckA tpiA tpiA pgk pgk APF19491.1 APF19491.1 APF19535.1 APF19535.1 APF19601.1 APF19601.1 eno eno Cabys_291 Cabys_291 Cabys_292 Cabys_292 Cabys_293 Cabys_293 Cabys_294 Cabys_294 APF19761.1 APF19761.1 APF19762.1 APF19762.1 acsA acsA deoC deoC lipA lipA APF20110.1 APF20110.1 ackA ackA APF20210.1 APF20210.1 sucD sucD sucC sucC APF20253.1 APF20253.1 APF20254.1 APF20254.1 APF20497.1 APF20497.1 APF20528.1 APF20528.1 APF20544.1 APF20544.1 APF20545.1 APF20545.1 APF20546.1 APF20546.1 mdh mdh APF20636.1 APF20636.1 APF20753.1 APF20753.1 APF20818.1 APF20818.1 APF20819.1 APF20819.1 APF20820.1 APF20820.1 APF20949.1 APF20949.1 Cabys_483 Cabys_483 Cabys_569 Cabys_569 Cabys_704 Cabys_704 Cabys_724 Cabys_724 Cabys_78 Cabys_78 Cabys_793 Cabys_793 Cabys_801 Cabys_801 Cabys_82 Cabys_82 pgi pgi Cabys_880 Cabys_880 Cabys_881 Cabys_881 Cabys_882 Cabys_882
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
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Your Input:
Cabys_115Aspartate aminotransferase. (399 aa)
APF17904.1Glutamate dehydrogenase (NADP); Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (453 aa)
APF17907.1Glutamate dehydrogenase (NAD(P)+); Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (428 aa)
deoBdeoB phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family. (389 aa)
pfpPfp 6-phosphofructokinase 1; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (445 aa)
pfkApfkA 6-phosphofructokinase 1; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (365 aa)
APF18095.1Acetyltransferase. (710 aa)
APF18121.1D-lactate dehydrogenase. (942 aa)
APF18152.1Pyruvate phosphate dikinase; Belongs to the PEP-utilizing enzyme family. (893 aa)
APF18155.1Glycerate 2-kinase. (440 aa)
APF18301.1Glutamate dehydrogenase (NAD/NADP); Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (413 aa)
Cabys_156Pyruvate kinase; Belongs to the pyruvate kinase family. (474 aa)
APF18309.1Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (671 aa)
talTal transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. (215 aa)
tal-2Tal transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. (215 aa)
APF18336.1Mannose-6-phosphate isomerase, type 1. (405 aa)
APF18412.1Acyl-CoA dehydrogenase. (383 aa)
APF18440.1Aldehyde dehydrogenase (NAD+); Belongs to the aldehyde dehydrogenase family. (473 aa)
APF18452.12-oxoglutarate ferredoxin oxidoreductase subunit alpha. (610 aa)
APF18453.12-oxoglutarate ferredoxin oxidoreductase subunit beta. (345 aa)
fumCfumC fumarase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (461 aa)
Cabys_172Fumarate hydratase, class I. (194 aa)
Cabys_173Fumarate hydratase, class I. (289 aa)
APF18488.1Glutamate synthase (NADH) large subunit. (1504 aa)
APF18489.1Glutamate synthase (NADH) small subunit. (471 aa)
APF18526.1Isocitrate dehydrogenase; Belongs to the monomeric-type IDH family. (743 aa)
fbaFructose-bisphosphate aldolase, class I. (354 aa)
APF18557.1L-fuculose-phosphate aldolase. (427 aa)
APF18558.1L-fuculose-phosphate aldolase. (261 aa)
APF18636.1propionyl-CoA carboxylase carboxyltransferase subunit. (516 aa)
APF18640.1Succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase. (453 aa)
APF18643.18-oxo-dGTP pyrophosphatase MutT, NUDIX family. (185 aa)
APF18660.12-oxoglutarate dehydrogenase E1 component. (932 aa)
APF18661.12-oxoglutarate dehydrogenase E2 component. (411 aa)
gcvPAgcvPA glycine dehydrogenase (decarboxylating) alpha subunit; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (429 aa)
gcvPBgcvPB glycine dehydrogenase (decarboxylating) beta subunit; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. (484 aa)
pdxSpdxS pyridoxal phosphate synthase yaaD subunit; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. (295 aa)
APF18683.1Pyridoxal phosphate synthase yaaE subunit. (190 aa)
glmSglmS glucosamine--fructose-6-phosphate aminotransferase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (609 aa)
Cabys_20Phosphate acetyltransferase. (326 aa)
APF18800.1Aldehyde dehydrogenase (NAD+); Belongs to the aldehyde dehydrogenase family. (513 aa)
APF18802.1L-glutamine synthetase. (728 aa)
APF18805.1Alcohol dehydrogenase, propanol-preferring. (342 aa)
APF18831.1Glutamine synthetase. (457 aa)
gcvHgcvH glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (125 aa)
Cabys_22Citrate synthase; Belongs to the citrate synthase family. (435 aa)
APF18996.1Ribose 5-phosphate isomerase B. (209 aa)
APF19000.1Lipoate-protein ligase A. (333 aa)
APF19022.1Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (358 aa)
APF19062.1Allosteric NADP-dependent malic enzyme. (748 aa)
APF19135.1Hypothetical protein. (92 aa)
APF19136.1acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (365 aa)
APF19138.1hydroxymethylglutaryl-CoA synthase. (354 aa)
APF19152.1methylglutaconyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (261 aa)
APF19170.1Acylphosphatase. (92 aa)
fbpFbp D-fructose 1,6-bisphosphatase; Belongs to the FBPase class 1 family. (338 aa)
gcvTgcvT aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine. (358 aa)
APF19334.1Phosphoenolpyruvate carboxykinase (ATP). (613 aa)
APF19335.1Aspartate/methionine/tyrosine aminotransferase. (782 aa)
Cabys_262Pyruvate-ferredoxin/flavodoxin oxidoreductase. (1192 aa)
APF19382.13-isopropylmalate dehydrogenase. (395 aa)
pckApckA phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (534 aa)
tpiAtpiA triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (255 aa)
pgkPgk phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (398 aa)
APF19491.1Glyceraldehyde-3-phosphate dehydrogenase (NAD+); Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (333 aa)
APF19535.1Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (223 aa)
APF19601.1butyryl-CoA dehydrogenase/short/branched chain acyl-CoA dehydrogenase. (385 aa)
enoEno enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (427 aa)
Cabys_2913-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (429 aa)
Cabys_292Short chain enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (669 aa)
Cabys_293Electron transfer flavoprotein beta subunit. (249 aa)
Cabys_294Electron transfer flavoprotein alpha subunit apoprotein. (317 aa)
APF19761.13-hydroxybutyryl-CoA dehydrogenase. (281 aa)
APF19762.1acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (395 aa)
acsAacsA acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (633 aa)
deoCdeoC deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (278 aa)
lipAlipA lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (320 aa)
APF20110.1Short chain enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (261 aa)
ackAackA acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (401 aa)
APF20210.13-hydroxybutyryl-CoA dehydrogenase. (314 aa)
sucDsuccinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (293 aa)
sucCsucC succinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (386 aa)
APF20253.12-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase). (430 aa)
APF20254.12-oxoisovalerate dehydrogenase E1 component. (678 aa)
APF20497.1Glutamine cyclotransferase. (529 aa)
APF20528.1Isocitrate dehydrogenase (NAD+). (341 aa)
APF20544.1Dihydrolipoamide dehydrogenase. (475 aa)
APF20545.1Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase). (442 aa)
APF20546.1Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (890 aa)
mdhMdh malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. (318 aa)
APF20636.1Bifunctional phosphoglucose/phosphomannose isomerase. (346 aa)
APF20753.1Ribose-phosphate pyrophosphokinase; Belongs to the ribose-phosphate pyrophosphokinase family. (348 aa)
APF20818.1Succinate dehydrogenase subunit C. (231 aa)
APF20819.1Succinate dehydrogenase subunit A. (636 aa)
APF20820.1Succinate dehydrogenase / fumarate reductase iron-sulfur subunit. (251 aa)
APF20949.1Ribose-5-phosphate isomerase. (146 aa)
Cabys_483glutaryl-CoA dehydrogenase. (387 aa)
Cabys_569Alcohol dehydrogenase. (381 aa)
Cabys_704Malate dehydrogenase (NAD); Catalyzes the conversion of lactate to pyruvate. (316 aa)
Cabys_724Glyoxylate reductase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (323 aa)
Cabys_78Dihydrolipoamide dehydrogenase. (463 aa)
Cabys_7933-hydroxyisobutyrate dehydrogenase/glyoxylate/succinic semialdehyde reductase. (286 aa)
Cabys_801Sulfide dehydrogenase (flavoprotein) subunit SudA. (475 aa)
Cabys_82Aconitase. (755 aa)
pgiPgi glucose-6-phosphate isomerase; Belongs to the GPI family. (459 aa)
Cabys_880Electron transfer flavoprotein beta subunit. (296 aa)
Cabys_881Electron transfer flavoprotein alpha subunit apoprotein. (339 aa)
Cabys_882Hypothetical protein. (573 aa)
Your Current Organism:
Caldithrix abyssi
NCBI taxonomy Id: 880073
Other names: C. abyssi DSM 13497, Caldithrix abyssi DSM 13497, Caldithrix abyssi LF13, Caldithrix abyssi str. DSM 13497, Caldithrix abyssi strain DSM 13497
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