(28 nodes) (2022) Comparative Investigation of Gene Regulatory Processes Underlying Avian Influenza Viruses in Chicken and Duck. network (Anas platyrhynchos)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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textmining

co-expression

protein homology

Your Input:
	SRF	Serum response factor. (516 aa)
	SMAD4	Mothers against decapentaplegic homolog. (551 aa)
	JUN	Jun proto-oncogene, AP-1 transcription factor subunit. (276 aa)
	IRF4	Interferon regulatory factor 4. (446 aa)
	RUNX2	RUNX family transcription factor 2. (510 aa)
	IRF7	Interferon regulatory factor 7. (523 aa)
	NKX2-2	Homeobox domain-containing protein. (206 aa)
	DLX3	Distal-less homeobox 3. (284 aa)
	NKX6-1	NK6 homeobox 1. (245 aa)
	STAT4	Signal transducer and activator of transcription. (757 aa)
	FOS	Fos proto-oncogene, AP-1 transcription factor subunit. (369 aa)
	ETS1	ETS proto-oncogene 1, transcription factor. (491 aa)
	FOXL2	Forkhead box L2. (307 aa)
	SIX3	SIX homeobox 3. (318 aa)
	TLR7	Toll like receptor 7; Belongs to the Toll-like receptor family. (1089 aa)
	RNF135	B30.2/SPRY domain-containing protein. (249 aa)
	RUNX1	Runt-related transcription factor. (504 aa)
	SMAD3	Mothers against decapentaplegic homolog. (426 aa)
	STAT3	Signal transducer and activator of transcription. (942 aa)
	HOXD13	Homeobox D13. (235 aa)
	EP300	E1A binding protein p300. (2355 aa)
	LHX3	LIM homeobox 3. (395 aa)
	FOXO3	Fork-head domain-containing protein. (665 aa)
	STAT1	Signal transducer and activator of transcription. (869 aa)
	EPAS1	Endothelial PAS domain protein 1. (876 aa)
	FOXC1	Forkhead box C1. (250 aa)
	SALL3	Spalt like transcription factor 3. (1256 aa)
	ARNT2	Aryl hydrocarbon receptor nuclear translocator 2. (746 aa)

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARNT2	EP300	ENSAPLP00000019388	ENSAPLP00000010252	Aryl hydrocarbon receptor nuclear translocator 2.	E1A binding protein p300.	0.643
ARNT2	EPAS1	ENSAPLP00000019388	ENSAPLP00000016796	Aryl hydrocarbon receptor nuclear translocator 2.	Endothelial PAS domain protein 1.	0.910
DLX3	LHX3	ENSAPLP00000025479	ENSAPLP00000010801	Distal-less homeobox 3.	LIM homeobox 3.	0.426
DLX3	SALL3	ENSAPLP00000025479	ENSAPLP00000016910	Distal-less homeobox 3.	Spalt like transcription factor 3.	0.417
EP300	ARNT2	ENSAPLP00000010252	ENSAPLP00000019388	E1A binding protein p300.	Aryl hydrocarbon receptor nuclear translocator 2.	0.643
EP300	EPAS1	ENSAPLP00000010252	ENSAPLP00000016796	E1A binding protein p300.	Endothelial PAS domain protein 1.	0.874
EP300	ETS1	ENSAPLP00000010252	ENSAPLP00000022251	E1A binding protein p300.	ETS proto-oncogene 1, transcription factor.	0.510
EP300	FOS	ENSAPLP00000010252	ENSAPLP00000022407	E1A binding protein p300.	Fos proto-oncogene, AP-1 transcription factor subunit.	0.757
EP300	FOXO3	ENSAPLP00000010252	ENSAPLP00000011053	E1A binding protein p300.	Fork-head domain-containing protein.	0.781
EP300	IRF7	ENSAPLP00000010252	ENSAPLP00000026565	E1A binding protein p300.	Interferon regulatory factor 7.	0.641
EP300	JUN	ENSAPLP00000010252	ENSAPLP00000031204	E1A binding protein p300.	Jun proto-oncogene, AP-1 transcription factor subunit.	0.903
EP300	RUNX1	ENSAPLP00000010252	ENSAPLP00000006638	E1A binding protein p300.	Runt-related transcription factor.	0.714
EP300	RUNX2	ENSAPLP00000010252	ENSAPLP00000030547	E1A binding protein p300.	RUNX family transcription factor 2.	0.635
EP300	SMAD3	ENSAPLP00000010252	ENSAPLP00000006649	E1A binding protein p300.	Mothers against decapentaplegic homolog.	0.689
EP300	SMAD4	ENSAPLP00000010252	ENSAPLP00000003446	E1A binding protein p300.	Mothers against decapentaplegic homolog.	0.797
EP300	STAT1	ENSAPLP00000010252	ENSAPLP00000013135	E1A binding protein p300.	Signal transducer and activator of transcription.	0.707
EP300	STAT3	ENSAPLP00000010252	ENSAPLP00000007496	E1A binding protein p300.	Signal transducer and activator of transcription.	0.927
EP300	STAT4	ENSAPLP00000010252	ENSAPLP00000024437	E1A binding protein p300.	Signal transducer and activator of transcription.	0.707
EPAS1	ARNT2	ENSAPLP00000016796	ENSAPLP00000019388	Endothelial PAS domain protein 1.	Aryl hydrocarbon receptor nuclear translocator 2.	0.910
EPAS1	EP300	ENSAPLP00000016796	ENSAPLP00000010252	Endothelial PAS domain protein 1.	E1A binding protein p300.	0.874