STRINGSTRING
APH1A APH1A ARHGEF5 ARHGEF5 ARHGEF7 ARHGEF7 ARHGEF10 ARHGEF10 ARHGEF15 ARHGEF15 ARHGEF2 ARHGEF2 ARHGEF10L ARHGEF10L ENSFDAP00000002920 ENSFDAP00000002920 VAV3 VAV3 GNA13 GNA13 AATF AATF ARHGEF4 ARHGEF4 MAPK8 MAPK8 RAC1 RAC1 ARHGEF26 ARHGEF26 MCF2 MCF2 SESTD1 SESTD1 BAD BAD NGFR NGFR SOS1 SOS1 VAV1 VAV1 ARHGEF9 ARHGEF9 ARHGEF3 ARHGEF3 H920_12778 H920_12778 FGD3 FGD3 VAV2 VAV2 SOS2 SOS2 ARHGEF37 ARHGEF37 NET1 NET1 NGF NGF Casp3 Casp3 LOC104862966 LOC104862966 PSEN2 PSEN2 MCF2L MCF2L ITSN1 ITSN1 Arhgef18 Arhgef18 Gsap Gsap YWHAE YWHAE ITGB3BP ITGB3BP Arhgef19 Arhgef19 ARHGEF6 ARHGEF6 Akap13 Akap13 TIAM1 TIAM1 ENSFDAP00000013841 ENSFDAP00000013841 ARHGEF12 ARHGEF12 RPS27A RPS27A FGD4 FGD4 FGD1 FGD1 TRAF6 TRAF6 ARHGEF17 ARHGEF17 Arhgef25 Arhgef25 PLEKHG5 PLEKHG5 ARHGEF1 ARHGEF1 PSEN1 PSEN1 ECT2 ECT2 PSENEN PSENEN ENSFDAP00000017172 ENSFDAP00000017172 LOC104867783 LOC104867783 SQSTM1 SQSTM1 APH1B APH1B Ubc Ubc Tgm3 Tgm3 ARHGEF39 ARHGEF39 TGM6 TGM6 BCL2L11 BCL2L11 ARHGEF11 ARHGEF11 ARHGEF16 ARHGEF16 TRIO TRIO ABR ABR KALRN KALRN NGEF NGEF CASP2 CASP2 BEX3 BEX3 UBA52 UBA52 ARHGEF40 ARHGEF40 Arhgef33 Arhgef33 NCSTN NCSTN
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
APH1AGamma-secretase subunit APH-1A. (265 aa)
ARHGEF5Rho guanine nucleotide exchange factor 5. (1372 aa)
ARHGEF7Rho guanine nucleotide exchange factor 7. (809 aa)
ARHGEF10Rho guanine nucleotide exchange factor 10. (1325 aa)
ARHGEF15Rho guanine nucleotide exchange factor 15. (845 aa)
ARHGEF2Rho/Rac guanine nucleotide exchange factor 2. (957 aa)
ARHGEF10LRho guanine nucleotide exchange factor 10-like protein. (1222 aa)
ENSFDAP00000002920annotation not available (87 aa)
VAV3Guanine nucleotide exchange factor VAV3. (779 aa)
GNA13Guanine nucleotide-binding protein subunit alpha-13. (373 aa)
AATFProtein AATF. (494 aa)
ARHGEF4Rho guanine nucleotide exchange factor 4. (484 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
RAC1Ras-related C3 botulinum toxin substrate 1. (199 aa)
ARHGEF26Rho guanine nucleotide exchange factor 26. (869 aa)
MCF2Proto-oncogene DBL. (1010 aa)
SESTD1SEC14 domain and spectrin repeat-containing protein 1. (696 aa)
BADBcl2 antagonist of cell death. (162 aa)
NGFRTumor necrosis factor receptor superfamily member 16. (362 aa)
SOS1Son of sevenless like protein 1. (1289 aa)
VAV1Proto-oncogene vav. (714 aa)
ARHGEF9Rho guanine nucleotide exchange factor 9. (512 aa)
ARHGEF3Rho guanine nucleotide exchange factor 3. (558 aa)
H920_12778Dynamin-binding protein. (219 aa)
FGD3FYVE, RhoGEF and PH domain-containing protein 3. (736 aa)
VAV2Guanine nucleotide exchange factor VAV2. (771 aa)
SOS2Son of sevenless like protein 2. (1310 aa)
ARHGEF37Rho guanine nucleotide exchange factor 37. (674 aa)
NET1Neuroepithelial cell-transforming gene 1 protein. (553 aa)
NGFBeta-nerve growth factor; Belongs to the NGF-beta family. (305 aa)
Casp3Caspase-3; Belongs to the peptidase C14A family. (277 aa)
LOC104862966T-lymphoma invasion and metastasis-inducing protein 2. (916 aa)
PSEN2Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (447 aa)
MCF2LGuanine nucleotide exchange factor DBS. (1121 aa)
ITSN1Intersectin-1. (1716 aa)
Arhgef18Rho guanine nucleotide exchange factor 18. (788 aa)
GsapGamma-secretase-activating protein. (175 aa)
YWHAE14-3-3 protein epsilon; Belongs to the 14-3-3 family. (255 aa)
ITGB3BPIntegrin subunit beta 3 binding protein. (180 aa)
Arhgef19Rho guanine nucleotide exchange factor 19. (423 aa)
ARHGEF6Rho guanine nucleotide exchange factor 6. (789 aa)
Akap13A-kinase anchor protein 13. (1430 aa)
TIAM1T-lymphoma invasion and metastasis-inducing protein 1. (1590 aa)
ENSFDAP00000013841annotation not available (257 aa)
ARHGEF12Rho guanine nucleotide exchange factor 12. (1543 aa)
RPS27AUbiquitin-40S ribosomal protein S27a. (156 aa)
FGD4FYVE, RhoGEF and PH domain-containing protein 4. (769 aa)
FGD1FYVE, RhoGEF and PH domain-containing protein 1. (934 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (543 aa)
ARHGEF17Rho guanine nucleotide exchange factor 17. (1835 aa)
Arhgef25Rho guanine nucleotide exchange factor 25. (618 aa)
PLEKHG5Pleckstrin homology and RhoGEF domain containing G5. (1028 aa)
ARHGEF1Rho guanine nucleotide exchange factor 1. (943 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa)
ECT2Protein ECT2. (914 aa)
PSENENGamma-secretase subunit PEN-2. (101 aa)
ENSFDAP00000017172annotation not available (132 aa)
LOC104867783Rho guanine nucleotide exchange factor 19. (55 aa)
SQSTM1Sequestosome-1. (400 aa)
APH1BGamma-secretase subunit APH-1B. (257 aa)
UbcPolyubiquitin-B. (235 aa)
Tgm3Protein-glutamine gamma-glutamyltransferase E. (695 aa)
ARHGEF39Uncharacterized protein. (335 aa)
TGM6Protein-glutamine gamma-glutamyltransferase 6. (706 aa)
BCL2L11BCL2 like 11. (195 aa)
ARHGEF11Rho guanine nucleotide exchange factor 11. (1534 aa)
ARHGEF16Rho guanine nucleotide exchange factor 16. (707 aa)
TRIOTriple functional domain protein. (3024 aa)
ABRActive breakpoint cluster region-related protein. (853 aa)
KALRNKalirin. (2971 aa)
NGEFEphexin-1. (703 aa)
CASP2Caspase-2; Belongs to the peptidase C14A family. (452 aa)
BEX3Protein BEX3. (111 aa)
UBA52KxDL motif containing 1. (232 aa)
ARHGEF40Rho guanine nucleotide exchange factor 40. (1517 aa)
Arhgef33Rho guanine nucleotide exchange factor 33. (720 aa)
NCSTNNicastrin. (709 aa)
Your Current Organism:
Fukomys damarensis
NCBI taxonomy Id: 885580
Other names: Coetomys damarensis, Cryptomys damarensis, Damara mole rat, Damara mole-rat, F. damarensis
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.