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| CDH1 | Cadherin-1; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. E-cadherin is a ligand for integrin alpha- E/beta-7. (887 aa) | ||||
| ETS1 | Transforming protein p68/c-ets-1; Probable transcription factor. (497 aa) | ||||
| NKX2-5 | Homeobox protein Nkx-2.5; Implicated in commitment to and/or differentiation of the myocardial lineage. Binds to the core DNA motif of promoter. Belongs to the NK-2 homeobox family. (294 aa) | ||||
| GDF3 | CVg1 protein. (373 aa) | ||||
| CBFB | Uncharacterized protein. (187 aa) | ||||
| GFI1B | Zinc finger protein Gfi-1b; Essential transcriptional regulator necessary for development and differentiation of erythroid and megakaryocytic lineages. Alters histone methylation by recruiting histone methyltransferase to target genes promoters. Plays a role in heterochromatin formation. (337 aa) | ||||
| GPER1 | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (357 aa) | ||||
| TWIST2 | Dermo protein. (160 aa) | ||||
| SOX8 | Transcription factor SOX-8; May play a role in central nervous system, limb and facial development. May be involved in male sex determination. Binds the consensus motif 5'-[AT][AT]CAA[AT]G-3'. (470 aa) | ||||
| GATA5 | Transcription factor GATA-5; Probably involved in bone morphogenetic protein (BMP)- mediated cardiac-specific gene expression. Binds to BMP response element (BMPRE) DNA sequences within cardiac activating regions. (391 aa) | ||||
| WWOX | WW domain-containing oxidoreductase; Putative oxidoreductase. Acts as a tumor suppressor and plays a role in apoptosis. May function synergistically with p53/TP53 to control genotoxic stress-induced cell death. Plays a role in TGFB1 signaling and TGFB1-mediated cell death. May also play a role in tumor necrosis factor (TNF)-mediated cell death. Required for normal bone development. Inhibits Wnt signaling (By similarity). Belongs to the short-chain dehydrogenases/reductases (SDR) family. (414 aa) | ||||
| SEMA3D | Semaphorin-3D; Induces the collapse and paralysis of neuronal growth cones. Could potentially act as repulsive cues toward specific neuronal populations. Binds to neuropilin; Belongs to the semaphorin family. (761 aa) | ||||
| ZEB1 | Zinc finger E-box-binding homeobox 1; Acts as a transcriptional repressor. Positively regulates neuronal differentiation. Represses transcription by binding to the E box-containing promoter (By similarity). Binds to delta 1-crystallin enhancer core and represses lens-specific transcription. It binds as well many other non-lens specific DNA sequences. (1114 aa) | ||||
| TFAP2C | Transcription factor AP-2 gamma. (448 aa) | ||||
| SNAI1 | Snail like protein. (256 aa) | ||||
| TLE3 | TLE family member 3, transcriptional corepressor. (779 aa) | ||||
| TBX5 | T-box transcription factor TBX5; DNA-binding protein that regulates the transcription of several genes and is involved in heart development and limb pattern formation. May bind to the core DNA motif of promoters. (521 aa) | ||||
| LMCD1 | LIM and cysteine rich domains 1. (360 aa) | ||||
| LHX8 | Uncharacterized protein. (347 aa) | ||||
| ESR2 | Estrogen receptor beta; Binds estrogens with an affinity similar to that of ER-alpha, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner. Belongs to the nuclear hormone receptor family. NR3 subfamily. (472 aa) | ||||
| EP300 | E1A binding protein p300. (2450 aa) | ||||
| WT1 | Uncharacterized protein. (417 aa) | ||||
| SOX10 | Transcription factor SOX-10; Transcription factor that plays a central role in developing and mature glia. Specifically activates expression of myelin genes, during oligodendrocyte (OL) maturation, thereby playing a central role in oligodendrocyte maturation and CNS myelination. (461 aa) | ||||
| CFC1 | Cryptic protein; May play a role in mesoderm and/or neural patterning during gastrulation. (193 aa) | ||||
| TFAP2A | TF_AP-2 domain-containing protein. (437 aa) | ||||
| CITED2 | Cited2/melanocyte specific gene-related gene 1 MRG1. (236 aa) | ||||
| MSX1 | Homeobox protein GHOX-7; Probably plays a role in patterning events during embryonic limb development. May also be involved in programmed cell death. (288 aa) | ||||
| GREB1 | Uncharacterized protein. (1937 aa) | ||||
| TFAP2B | Transcription factor AP-2 beta. (449 aa) | ||||
| TFCP2L1 | Transcription factor CP2 like 1. (475 aa) | ||||
| GATA2 | GATA-binding factor 2; Transcriptional activator which probably serves as a general switch factor for cell-specific development. It binds to DNA sites with the consensus sequence 5'-[AT]GATA[AG]-3' within regulatory regions of genes. (466 aa) | ||||
| GATA4 | Transcription factor GATA-4; Transcriptional activator. Binds to the consensus sequence 5'-AGATAG-3' (By similarity). (410 aa) | ||||
| GATA6 | Transcription factor GATA-6; Transcriptional activator. (387 aa) | ||||
| IRX4 | Iroquois-class homeodomain protein IRX-4; Regulates the chamber-specific expression of myosin isoforms by activating the expression of the ventricle myosin heavy chain-1 (Vmhc1) and suppressing the expression of the atrial myosin heavy chain-1 (Amhc1) in the ventricles. May play a critical role in establishing chamber-specific gene expression in the developing heart; Belongs to the TALE/IRO homeobox family. (485 aa) | ||||
| ETV6 | Uncharacterized protein. (451 aa) | ||||
| PAX9 | Paired box protein Pax-9. (341 aa) | ||||
| TBX22 | T-box transcription factor Tbx22. (489 aa) | ||||
| TCF3 | BHLH domain-containing protein. (682 aa) | ||||
| EOMES | T-box_assoc domain-containing protein. (661 aa) | ||||
| KLF4 | Uncharacterized protein. (111 aa) | ||||
| FOXE3 | Forkhead box protein D3; Binds to the consensus sequence 5'-A[AT]T[AG]TTTGTTT-3' and acts as a transcriptional repressor. Also acts as a transcriptional activator. Promotes development of neural crest cells from neural tube progenitors. Restricts neural progenitor cells to the neural crest lineage while suppressing interneuron differentiation. Required for maintenance of pluripotent cells in the pre-implantation and peri- implantation stages of embryogenesis. (386 aa) | ||||
| TCF21 | BHLH domain-containing protein. (179 aa) | ||||
| NANOG | Homeobox protein NANOG; Transcription factor required for the maintenance of pluripotency and self-renewal of embryonic stem cells. Belongs to the Nanog homeobox family. (308 aa) | ||||
| ESRRB | Estrogen related receptor beta. (454 aa) | ||||
| SOX17 | Uncharacterized protein. (410 aa) | ||||
| FOXA2 | Fork-head domain-containing protein. (438 aa) | ||||
| TBX3 | T-box transcription factor TBX3; Transcriptional repressor involved in developmental processes. Probably plays a role in limb pattern formation. (732 aa) | ||||
| TWIST1 | CTwist. (190 aa) | ||||
| SOX2 | Transcription factor SOX-2; Transcriptional activator. Binds to the consensus DNA sequence 5'-TCATTGTTGTTG-3'. In cooperation with other transcription factors, binds to the promoter sequence of the crystallin gene to activate transcription in the lens. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal (By similarity). Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation. May function as a switch in neuronal development. (312 aa) | ||||
| LMO2 | LIM domain only 2. (216 aa) | ||||
| HAND2 | Heart- and neural crest derivatives-expressed protein 2; Essential for cardiac morphogenesis. Binds DNA on E-box consensus sequence 5'-CANNTG-3' (By similarity). Plays an important role in limb development, particularly in the establishment of anterior-posterior polarization of the limb bud. (216 aa) | ||||
| SALL4 | Uncharacterized protein. (1108 aa) | ||||
| PITX2 | Pituitary homeobox 2; May play an important role in development and maintenance of anterior structures. May play a role in determining left-right asymmetry and in vasculogenesis during avian embryogenesis. (333 aa) | ||||
| MSX2 | Homeobox protein MSX-2; Acts as a transcriptional regulator in bone development. Binds to DNA (By similarity). Morphogenetic role; Belongs to the Msh homeobox family. (259 aa) | ||||
| KCTD1 | Potassium channel tetramerization domain containing 1. (816 aa) | ||||
| TBX18 | Uncharacterized protein. (589 aa) | ||||
| OSR2 | Uncharacterized protein. (412 aa) | ||||
| FOXF1 | Forkhead box F1. (407 aa) | ||||
| ERG | Transcriptional regulator Erg; Acts as a transcriptional activator. (485 aa) | ||||
| ELF5 | E74 like ETS transcription factor 5. (258 aa) | ||||
| RUNX1T1 | Uncharacterized protein. (604 aa) | ||||
| FOXA1 | Forkhead box A1. (442 aa) | ||||
| ID2 | Transcriptional regulator Id2. (134 aa) | ||||
| MEF2C | Myocyte enhancer factor 2C. (483 aa) | ||||
| TBX20 | T-box transcription factor TBX20; Acts as a transcriptional regulator involved in heart developmental processes. (440 aa) | ||||
| TFAP2E | Transcription factor AP-2 epsilon. (541 aa) | ||||
| LDB1 | LIM domain-binding protein 1; Binds to the LIM domain of a wide variety of LIM domain- containing transcription factors. (416 aa) | ||||
| ZIC1 | Zinc finger protein ZIC 1; Acts as a transcriptional activator. Involved in neurogenesis. Plays important roles in the early stage of organogenesis of the CNS, as well as during dorsal spinal cord development and maturation of the cerebellum. Binds to the minimal GLI-consensus sequence 5'-TGGGTGGTC-3' (By similarity). (444 aa) | ||||
| ZIC3 | Zinc finger protein Zic3. (464 aa) | ||||
| ZFPM2 | Zinc finger protein, FOG family member 2. (1151 aa) | ||||
| SOX7 | Uncharacterized protein. (377 aa) | ||||
| SNAI2 | Uncharacterized protein. (258 aa) | ||||
| SHOX2 | Short stature homeobox 2. (316 aa) | ||||
| TBX2 | T-box transcription factor 2. (693 aa) | ||||
| LEFTY1 | Left-right determination factor. (362 aa) | ||||
| NKX3-2 | Homeobox domain-containing protein. (275 aa) | ||||
| HHEX | Hematopoietically-expressed homeobox protein HHEX; Recognizes the DNA sequence 5'-ATTAA-3'. Transcriptional repressor. May play a role in hematopoietic differentiation. (320 aa) | ||||
| RUNX1 | Runt-related transcription factor. (472 aa) | ||||
| KLF-4 | Uncharacterized protein. (481 aa) | ||||
| ETS2 | Protein C-ets-2; Probable transcription factor; Belongs to the ETS family. (479 aa) | ||||
| ENSGALP00000067067 | Homeobox domain-containing protein. (190 aa) | ||||
| DLX3 | Homeobox domain-containing protein. (451 aa) | ||||
| ENSGALP00000067176 | TGF_BETA_2 domain-containing protein. (115 aa) | ||||
| ZFPM1 | Zinc finger protein, FOG family member 1. (1079 aa) | ||||
| GATA3 | GATA-binding factor 3; Transcriptional activator which probably serves as a general switch factor for cell-specific development. It binds to DNA sites with the consensus sequence 5'-[AT]GATA[AG]-3' within regulatory regions of genes. (444 aa) | ||||
| NPDC1 | POU domain, class 5, transcription factor 3; Required for the maintenance of pluripotency and self-renewal of embryonic stem cells. Transcriptional activator that binds the DNA consensus sequence 5'-ATGCAAAT-3'; Belongs to the POU transcription factor family. (427 aa) | ||||
| ZEB2 | Smad-interacting protein 1. (1214 aa) | ||||
| RUNX3 | RUNX family transcription factor 3. (607 aa) | ||||
| BARX1 | Homeobox protein BarH-like 1b; Transcription factor which is involved with the serum response factor (SRF) in the smooth muscle cell-specific transcription of the beta-tropomyosin gene in the upper digestive organs and their attached arteries; Belongs to the BAR homeobox family. (346 aa) | ||||
| NRIP1 | Nuclear receptor interacting protein 1. (1155 aa) | ||||
| TAL1 | T-cell acute lymphocytic leukemia protein 1 homolog; Implicated in the genesis of hemopoietic malignancies. It may play an important role in hemopoietic differentiation. (396 aa) | ||||
| ENSGALP00000073834 | Uncharacterized protein. (1340 aa) | ||||
| ESR1 | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (651 aa) | ||||