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| | CDC27 | Uncharacterized protein. (833 aa) |
| | SPDL1 | Protein Spindly; Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex; Belongs to the Spindly family. (608 aa) |
| | ANAPC7 | Anaphase promoting complex subunit 7. (565 aa) |
| | ERCC6L | ERCC excision repair 6 like, spindle assembly checkpoint helicase. (1280 aa) |
| | MAD1L1 | Mitotic arrest deficient 1 like 1. (717 aa) |
| | ANAPC16 | Anaphase promoting complex subunit 16. (134 aa) |
| | DYNLL2 | Dynein light chain. (89 aa) |
| | PAFAH1B1 | Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration. (410 aa) |
| | PLK1 | Serine/threonine-protein kinase PLK. (595 aa) |
| | PPP2CA | Serine/threonine-protein phosphatase. (309 aa) |
| | DYNLL1 | Dynein light chain. (89 aa) |
| | CDC23 | Cell division cycle 23. (595 aa) |
| | ZWILCH | Zwilch kinetochore protein. (536 aa) |
| | NUP85 | Nuclear pore complex protein Nup85; Functions as a component of the nuclear pore complex (NPC). (843 aa) |
| | BUB1 | Uncharacterized protein. (1087 aa) |
| | DYNC1I2 | WD_REPEATS_REGION domain-containing protein. (608 aa) |
| | DYNC1I1 | Dynein cytoplasmic 1 intermediate chain 1. (625 aa) |
| | CENPF | Uncharacterized protein. (2935 aa) |
| | PPP2R5A | Serine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (476 aa) |
| | CDC20 | WD_REPEATS_REGION domain-containing protein. (507 aa) |
| | KIF2C | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (733 aa) |
| | PPP2CB | Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform; PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase; Belongs to the PPP phosphatase family. PP-1 subfamily. (309 aa) |
| | SPC25 | Uncharacterized protein. (234 aa) |
| | NUP133 | Nucleoporin 133. (1181 aa) |
| | UBE2E1 | Ubiquitin conjugating enzyme E2 E1; Belongs to the ubiquitin-conjugating enzyme family. (193 aa) |
| | DYNC1LI1 | Cytoplasmic dynein 1 light intermediate chain 1; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes (By similarity); Belongs to the dynein light intermediate chain family. (515 aa) |
| | CENPC | Uncharacterized protein. (872 aa) |
| | PPP2R5E | Serine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (467 aa) |
| | CENPM | Centromere protein M; Component of the CENPA-HI complex, a centromeric complex involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. (177 aa) |
| | RANGAP1 | RanGAP1_C domain-containing protein. (579 aa) |
| | KIF18A | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (969 aa) |
| | NUP43 | Nucleoporin 43. (374 aa) |
| | NUP37 | WD_REPEATS_REGION domain-containing protein. (326 aa) |
| | CENPE | Centromere protein E; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (2228 aa) |
| | NDC80 | Kinetochore protein NDC80 homolog; Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore. The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules. May play a role in chromosome congression and may be essential for the end-on attachment of the kinetochores t [...] (640 aa) |
| | CDC16 | TPR_REGION domain-containing protein. (623 aa) |
| | CENPH | Centromere protein H; Component of the CENPA-HI complex, a centromeric complex involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. Required for the localization of CENPC but not CENPA to the centromere. It however may be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex; Belongs to the CENP-H/MCM16 family. (235 aa) |
| | UBE2D1 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (147 aa) |
| | SKA2 | Spindle and kinetochore associated complex subunit 2. (228 aa) |
| | DYNC1H1 | Dynein cytoplasmic 1 heavy chain 1. (4652 aa) |
| | SGO1 | Shugoshin_C domain-containing protein. (607 aa) |
| | NSL1 | Nsl1 protein. (290 aa) |
| | BIRC5 | Uncharacterized protein. (142 aa) |
| | CENPN | Centromere protein N; Probable component of a centromeric complex involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation; Belongs to the CENP-N/CHL4 family. (352 aa) |
| | CENPS | Centromere protein S; DNA-binding component of the Fanconi anemia (FA) core complex. Required for the normal activation of the FA pathway, leading to monoubiquitination of the FANCI-FANCD2 complex in response to DNA damage, cellular resistance to DNA cross-linking drugs, and prevention of chromosomal breakage. In complex with CENPX (MHF heterodimer), crucial cofactor for FANCM in both binding and ATP- dependent remodeling of DNA. Stabilizes FANCM. In complex with CENPX and FANCM (but not other FANC proteins), rapidly recruited to blocked forks and promotes gene conversion at blocked re [...] (139 aa) |
| | UBE2C | Ubiquitin conjugating enzyme E2 C; Belongs to the ubiquitin-conjugating enzyme family. (179 aa) |
| | RPS27 | 40S ribosomal protein S27. (84 aa) |
| | RCC2 | Regulator of chromosome condensation 2. (529 aa) |
| | SEH1L | SEH1 like nucleoporin; Belongs to the WD repeat SEC13 family. (419 aa) |
| | DSN1 | Dsn1 protein. (349 aa) |
| | NDE1 | Nuclear distribution protein nudE homolog 1; Required for centrosome duplication and formation and function of the mitotic spindle; Belongs to the nudE family. (342 aa) |
| | CLASP1 | Cytoplasmic linker associated protein 1. (1499 aa) |
| | XPO1 | Importin N-terminal domain-containing protein. (1071 aa) |
| | ANAPC4 | Anaphase promoting complex subunit 4. (838 aa) |
| | NUP98 | Nucleoporin 98. (1772 aa) |
| | CENPT | Centromere protein T; Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation (By similarity). The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres (By similarity). Part of a nucleosome-associated complex that binds specifically to histone H3-containing nucleosomes at the centromere, as opposed to nucleosomes containing CENPA. Component of the heterotetrameric CENP [...] (649 aa) |
| | NDEL1 | Nuclear distribution protein nudE-like 1; Required for organization of the cellular microtubule array and microtubule anchoring at the centrosome. Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Positively regulates lysosome peripheral distribution and ruffled border formation in osteoclasts. (358 aa) |
| | ANAPC15 | Anaphase promoting complex subunit 15. (121 aa) |
| | ZW10 | Uncharacterized protein. (781 aa) |
| | CENPI | Centromere protein I; Component of the CENPA-HI complex, a centromeric complex involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. Required for the localization of CENPC but not CENPA to the centromere. It however may be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex. (753 aa) |
| | BUB1B | BUB1 N-terminal domain-containing protein. (1086 aa) |
| | MAD2L1 | HORMA domain-containing protein. (206 aa) |
| | PPP1CC | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (347 aa) |
| | SEC13 | WD_REPEATS_REGION domain-containing protein; Belongs to the WD repeat SEC13 family. (579 aa) |
| | ANAPC2 | Anaphase promoting complex subunit 2; Belongs to the cullin family. (884 aa) |
| | BUB3 | WD_REPEATS_REGION domain-containing protein. (392 aa) |
| | CENPL | Centromere protein L; Component of the CENPA-HI complex, a centromeric complex involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. (344 aa) |
| | PPP2R5D | Serine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (543 aa) |
| | LOC776067-2 | Uncharacterized protein. (1667 aa) |
| | SGO2 | Shugoshin_C domain-containing protein. (958 aa) |
| | NNF1 | Uncharacterized protein. (279 aa) |
| | CLIP1 | CAP-Gly domain-containing linker protein 1; Binds to the plus end of microtubules and regulates the dynamics of the microtubule cytoskeleton. Promotes microtubule growth and microtubule bundling. Links cytoplasmic vesicles to microtubules and thereby plays an important role in intracellular vesicle trafficking. Plays a role macropinocytosis and endosome trafficking. (1444 aa) |
| | PPP2R5C | Serine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (580 aa) |
| | ANAPC1 | Anaphase promoting complex subunit 1. (1948 aa) |
| | UBE2S | Ubiquitin conjugating enzyme E2 S; Belongs to the ubiquitin-conjugating enzyme family. (268 aa) |
| | AHCTF1 | Uncharacterized protein. (2277 aa) |
| | ENSGALP00000068316 | Shugoshin_C domain-containing protein. (1007 aa) |
| | CLASP2 | Uncharacterized protein. (1506 aa) |
| | DYNC1LI2 | Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (534 aa) |
| | CKAP5 | Uncharacterized protein. (2073 aa) |
| | ANAPC10 | DOC domain-containing protein. (255 aa) |
| | ENSGALP00000071775 | RING-type domain-containing protein. (343 aa) |
| | NUP107 | Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC). (917 aa) |
| | CDC26 | Uncharacterized protein. (84 aa) |
