(24 nodes) Positive regulation of viral process network (Gallus gallus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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protein homology

Your Input:
	TMEM39B	Uncharacterized protein. (489 aa)
	ATG12	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (146 aa)
	VPS37B	VPS37B subunit of ESCRT-I. (283 aa)
	STAU1	Uncharacterized protein. (712 aa)
	TBC1D20	TBC1 domain family member 20. (394 aa)
	TSG101	Uncharacterized protein. (390 aa)
	TMPRSS4	Uncharacterized protein; Belongs to the peptidase S1 family. (405 aa)
	PPID	Peptidylprolyl isomerase D. (370 aa)
	CG-1B	Beta-galactoside-binding lectin; This protein binds beta-galactoside. May participate in host antiviral defense through specific interaction with glycans on the viral envelope glycoproteins. (135 aa)
	CNOT7	CCR4-NOT transcription complex subunit 7; Has 3'-5' poly(A) exoribonuclease activity for synthetic poly(A) RNA substrate. Catalytic component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA- mediated repression, translational repression during translational initiation and general transcription regulation. During miRNA-mediated repression the complex seems also to act as translational repressor during translational initiation. Additional complex functions may be a consequence [...] (285 aa)
	TMEM39A	Transmembrane protein 39A. (551 aa)
	CG-16	16 kDa beta-galactoside-binding lectin; This protein binds beta-galactoside. Its physiological function is not yet known. It may be involved in the regulation of differentiation. (126 aa)
	FKBP6	Peptidylprolyl isomerase. (319 aa)
	RSF1	Remodeling and spacing factor 1. (1392 aa)
	ATG5	Autophagy protein 5; Involved in autophagic vesicle formation. (288 aa)
	PPIE	Peptidyl-prolyl cis-trans isomerase E; Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins; Belongs to the cyclophilin-type PPIase family. PPIase E subfamily. (321 aa)
	PPARA	Uncharacterized protein. (468 aa)
	C9orf69	Uncharacterized protein. (139 aa)
	NR5A2	Nuclear receptor subfamily 5 group A member 2; Nuclear receptor that acts as a key metabolic sensor by regulating the expression of genes involved in bile acid synthesis, cholesterol homeostasis and triglyceride synthesis. Together with the oxysterol receptors NR1H3/LXR-alpha and NR1H2/LXR-beta, acts as an essential transcriptional regulator of lipid metabolism (By similarity). Activates the transcription of CYP2C38 (By similarity). (541 aa)
	CD74	Invariant chain isoform p41. (286 aa)
	CD4	Uncharacterized protein. (487 aa)
	ADAR	RNA-specific Adenosine deaminase Transcript variant M. (1153 aa)
	LARP1	La ribonucleoprotein domain family member 1. (1046 aa)
	PDE12	Phosphodiesterase 12. (584 aa)

Your Current Organism:

Gallus gallus

NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATG12	ATG5	ENSGALP00000003688	ENSGALP00000050539	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Autophagy protein 5; Involved in autophagic vesicle formation.	0.999
ATG5	ATG12	ENSGALP00000050539	ENSGALP00000003688	Autophagy protein 5; Involved in autophagic vesicle formation.	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	0.999
CD4	CD74	ENSGALP00000065611	ENSGALP00000063230	Uncharacterized protein.	Invariant chain isoform p41.	0.570
CD74	CD4	ENSGALP00000063230	ENSGALP00000065611	Invariant chain isoform p41.	Uncharacterized protein.	0.570
CNOT7	PDE12	ENSGALP00000022159	ENSGALP00000071249	CCR4-NOT transcription complex subunit 7; Has 3'-5' poly(A) exoribonuclease activity for synthetic poly(A) RNA substrate. Catalytic component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA- mediated repression, translational repression during translational initiation and general transcription regulation. During miRNA-mediated repression the complex seems also to act as translational repressor during translational initiation. Additional complex functions may be a consequence [...]	Phosphodiesterase 12.	0.649
LARP1	STAU1	ENSGALP00000069827	ENSGALP00000007529	La ribonucleoprotein domain family member 1.	Uncharacterized protein.	0.450
PDE12	CNOT7	ENSGALP00000071249	ENSGALP00000022159	Phosphodiesterase 12.	CCR4-NOT transcription complex subunit 7; Has 3'-5' poly(A) exoribonuclease activity for synthetic poly(A) RNA substrate. Catalytic component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA- mediated repression, translational repression during translational initiation and general transcription regulation. During miRNA-mediated repression the complex seems also to act as translational repressor during translational initiation. Additional complex functions may be a consequence [...]	0.649
PPID	PPIE	ENSGALP00000015366	ENSGALP00000050792	Peptidylprolyl isomerase D.	Peptidyl-prolyl cis-trans isomerase E; Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins; Belongs to the cyclophilin-type PPIase family. PPIase E subfamily.	0.401
PPIE	PPID	ENSGALP00000050792	ENSGALP00000015366	Peptidyl-prolyl cis-trans isomerase E; Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins; Belongs to the cyclophilin-type PPIase family. PPIase E subfamily.	Peptidylprolyl isomerase D.	0.401
STAU1	LARP1	ENSGALP00000007529	ENSGALP00000069827	Uncharacterized protein.	La ribonucleoprotein domain family member 1.	0.450
TSG101	VPS37B	ENSGALP00000010193	ENSGALP00000005929	Uncharacterized protein.	VPS37B subunit of ESCRT-I.	0.997
VPS37B	TSG101	ENSGALP00000005929	ENSGALP00000010193	VPS37B subunit of ESCRT-I.	Uncharacterized protein.	0.997