(24 nodes) Polymerase switching, and DNA polymerase complex network (Pavo cristatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CHTF8	Chromosome transmission fidelity factor 8. (112 aa)
	ENSPSTP00000004798	annotation not available (508 aa)
	POLE	DNA polymerase epsilon, catalytic subunit. (947 aa)
	RFC4	Replication factor C subunit 4. (362 aa)
	RFC2	Replication factor C subunit 2. (359 aa)
	MAD2L2	Mitotic arrest deficient 2 like 2. (211 aa)
	ENSPSTP00000008138	annotation not available (385 aa)
	RFC1	Replication factor C subunit 1. (1108 aa)
	RFC3	Replication factor C subunit 3. (299 aa)
	POLE4	DNA polymerase epsilon 4, accessory subunit. (98 aa)
	PRIM2	DNA primase subunit 2. (379 aa)
	POLD2	DNA polymerase delta 2, accessory subunit. (583 aa)
	HELQ	Helicase, POLQ like. (1046 aa)
	ENSPSTP00000018448	annotation not available (279 aa)
	PCNA	Proliferating cell nuclear antigen. (317 aa)
	ENSPSTP00000018748	annotation not available (231 aa)
	ATAD5	ATPase family AAA domain containing 5. (1073 aa)
	ENSPSTP00000020880	annotation not available (558 aa)
	ENSPSTP00000020927	annotation not available (155 aa)
	ENSPSTP00000021191	annotation not available (438 aa)
	ENSPSTP00000023403	annotation not available (943 aa)
	POLQ	DNA polymerase theta. (2446 aa)
	POLE2	DNA polymerase epsilon 2, accessory subunit. (486 aa)
	RFC5	Replication factor C subunit 5. (311 aa)

Your Current Organism:

Pavo cristatus

NCBI taxonomy Id: 9049
Other names: Indian peafowl, P. cristatus, blue peafowl

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATAD5	CHTF8	ENSPSTP00000019417	ENSPSTP00000000083	ATPase family AAA domain containing 5.	Chromosome transmission fidelity factor 8.	0.743
ATAD5	ENSPSTP00000004798	ENSPSTP00000019417	ENSPSTP00000004798	ATPase family AAA domain containing 5.	annotation not available	0.895
ATAD5	ENSPSTP00000008138	ENSPSTP00000019417	ENSPSTP00000008138	ATPase family AAA domain containing 5.	annotation not available	0.767
ATAD5	ENSPSTP00000018748	ENSPSTP00000019417	ENSPSTP00000018748	ATPase family AAA domain containing 5.	annotation not available	0.669
ATAD5	ENSPSTP00000020880	ENSPSTP00000019417	ENSPSTP00000020880	ATPase family AAA domain containing 5.	annotation not available	0.767
ATAD5	ENSPSTP00000020927	ENSPSTP00000019417	ENSPSTP00000020927	ATPase family AAA domain containing 5.	annotation not available	0.840
ATAD5	ENSPSTP00000021191	ENSPSTP00000019417	ENSPSTP00000021191	ATPase family AAA domain containing 5.	annotation not available	0.897
ATAD5	ENSPSTP00000023403	ENSPSTP00000019417	ENSPSTP00000023403	ATPase family AAA domain containing 5.	annotation not available	0.895
ATAD5	MAD2L2	ENSPSTP00000019417	ENSPSTP00000007660	ATPase family AAA domain containing 5.	Mitotic arrest deficient 2 like 2.	0.688
ATAD5	PCNA	ENSPSTP00000019417	ENSPSTP00000018659	ATPase family AAA domain containing 5.	Proliferating cell nuclear antigen.	0.993
ATAD5	POLD2	ENSPSTP00000019417	ENSPSTP00000015094	ATPase family AAA domain containing 5.	DNA polymerase delta 2, accessory subunit.	0.792
ATAD5	POLE	ENSPSTP00000019417	ENSPSTP00000006810	ATPase family AAA domain containing 5.	DNA polymerase epsilon, catalytic subunit.	0.906
ATAD5	POLE2	ENSPSTP00000019417	ENSPSTP00000024854	ATPase family AAA domain containing 5.	DNA polymerase epsilon 2, accessory subunit.	0.783
ATAD5	POLE4	ENSPSTP00000019417	ENSPSTP00000013373	ATPase family AAA domain containing 5.	DNA polymerase epsilon 4, accessory subunit.	0.754
ATAD5	PRIM2	ENSPSTP00000019417	ENSPSTP00000014188	ATPase family AAA domain containing 5.	DNA primase subunit 2.	0.873
ATAD5	RFC1	ENSPSTP00000019417	ENSPSTP00000011720	ATPase family AAA domain containing 5.	Replication factor C subunit 1.	0.974
ATAD5	RFC2	ENSPSTP00000019417	ENSPSTP00000006869	ATPase family AAA domain containing 5.	Replication factor C subunit 2.	0.998
ATAD5	RFC3	ENSPSTP00000019417	ENSPSTP00000012059	ATPase family AAA domain containing 5.	Replication factor C subunit 3.	0.999
ATAD5	RFC4	ENSPSTP00000019417	ENSPSTP00000006847	ATPase family AAA domain containing 5.	Replication factor C subunit 4.	0.999
ATAD5	RFC5	ENSPSTP00000019417	ENSPSTP00000026170	ATPase family AAA domain containing 5.	Replication factor C subunit 5.	0.999