(12 nodes) SUMO transferase activity network (Parus major)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CBX4	E3 SUMO-protein ligase CBX4. (578 aa)
	RNF212B	Ring finger protein 212B. (258 aa)
	UBE2I	Ubiquitin-conjugating enzyme E2 I. (325 aa)
	MUL1	Mitochondrial ubiquitin ligase activator of NFKB 1. (349 aa)
	PIAS2	E3 SUMO-protein ligase PIAS2 isoform X5. (724 aa)
	CBX7	Chromobox protein homolog 7 isoform X1. (245 aa)
	ZNF451	E3 SUMO-protein ligase ZNF451-like isoform X1. (1076 aa)
	PIAS1	E3 SUMO-protein ligase PIAS1 isoform X1. (651 aa)
	NSMCE2	E3 SUMO-protein ligase NSE2 isoform X1. (308 aa)
	RANBP2	E3 SUMO-protein ligase RanBP2 isoform X1. (3027 aa)
	PIAS4	E3 SUMO-protein ligase PIAS4 isoform X1. (492 aa)
	RNF212	Probable E3 SUMO-protein ligase RNF212. (301 aa)

Your Current Organism:

Parus major

NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CBX4	CBX7	ENSPMJP00000022464	ENSPMJP00000009758	E3 SUMO-protein ligase CBX4.	Chromobox protein homolog 7 isoform X1.	0.620
CBX4	UBE2I	ENSPMJP00000022464	ENSPMJP00000000951	E3 SUMO-protein ligase CBX4.	Ubiquitin-conjugating enzyme E2 I.	0.555
CBX7	CBX4	ENSPMJP00000009758	ENSPMJP00000022464	Chromobox protein homolog 7 isoform X1.	E3 SUMO-protein ligase CBX4.	0.620
NSMCE2	PIAS1	ENSPMJP00000014949	ENSPMJP00000013092	E3 SUMO-protein ligase NSE2 isoform X1.	E3 SUMO-protein ligase PIAS1 isoform X1.	0.602
NSMCE2	PIAS2	ENSPMJP00000014949	ENSPMJP00000003795	E3 SUMO-protein ligase NSE2 isoform X1.	E3 SUMO-protein ligase PIAS2 isoform X5.	0.602
NSMCE2	PIAS4	ENSPMJP00000014949	ENSPMJP00000015446	E3 SUMO-protein ligase NSE2 isoform X1.	E3 SUMO-protein ligase PIAS4 isoform X1.	0.602
NSMCE2	UBE2I	ENSPMJP00000014949	ENSPMJP00000000951	E3 SUMO-protein ligase NSE2 isoform X1.	Ubiquitin-conjugating enzyme E2 I.	0.891
PIAS1	NSMCE2	ENSPMJP00000013092	ENSPMJP00000014949	E3 SUMO-protein ligase PIAS1 isoform X1.	E3 SUMO-protein ligase NSE2 isoform X1.	0.602
PIAS1	PIAS2	ENSPMJP00000013092	ENSPMJP00000003795	E3 SUMO-protein ligase PIAS1 isoform X1.	E3 SUMO-protein ligase PIAS2 isoform X5.	0.921
PIAS1	PIAS4	ENSPMJP00000013092	ENSPMJP00000015446	E3 SUMO-protein ligase PIAS1 isoform X1.	E3 SUMO-protein ligase PIAS4 isoform X1.	0.930
PIAS1	UBE2I	ENSPMJP00000013092	ENSPMJP00000000951	E3 SUMO-protein ligase PIAS1 isoform X1.	Ubiquitin-conjugating enzyme E2 I.	0.895
PIAS1	ZNF451	ENSPMJP00000013092	ENSPMJP00000011437	E3 SUMO-protein ligase PIAS1 isoform X1.	E3 SUMO-protein ligase ZNF451-like isoform X1.	0.400
PIAS2	NSMCE2	ENSPMJP00000003795	ENSPMJP00000014949	E3 SUMO-protein ligase PIAS2 isoform X5.	E3 SUMO-protein ligase NSE2 isoform X1.	0.602
PIAS2	PIAS1	ENSPMJP00000003795	ENSPMJP00000013092	E3 SUMO-protein ligase PIAS2 isoform X5.	E3 SUMO-protein ligase PIAS1 isoform X1.	0.921
PIAS2	PIAS4	ENSPMJP00000003795	ENSPMJP00000015446	E3 SUMO-protein ligase PIAS2 isoform X5.	E3 SUMO-protein ligase PIAS4 isoform X1.	0.930
PIAS2	UBE2I	ENSPMJP00000003795	ENSPMJP00000000951	E3 SUMO-protein ligase PIAS2 isoform X5.	Ubiquitin-conjugating enzyme E2 I.	0.895
PIAS4	NSMCE2	ENSPMJP00000015446	ENSPMJP00000014949	E3 SUMO-protein ligase PIAS4 isoform X1.	E3 SUMO-protein ligase NSE2 isoform X1.	0.602
PIAS4	PIAS1	ENSPMJP00000015446	ENSPMJP00000013092	E3 SUMO-protein ligase PIAS4 isoform X1.	E3 SUMO-protein ligase PIAS1 isoform X1.	0.930
PIAS4	PIAS2	ENSPMJP00000015446	ENSPMJP00000003795	E3 SUMO-protein ligase PIAS4 isoform X1.	E3 SUMO-protein ligase PIAS2 isoform X5.	0.930
PIAS4	UBE2I	ENSPMJP00000015446	ENSPMJP00000000951	E3 SUMO-protein ligase PIAS4 isoform X1.	Ubiquitin-conjugating enzyme E2 I.	0.904