(26 nodes) Excitatory synapse network (Parus major)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSPMJP00000025711	annotation not available (236 aa)
	NETO1	Neuropilin and tolloid-like protein 1 isoform X1. (533 aa)
	SLC17A7	Vesicular glutamate transporter 1. (576 aa)
	SLC17A8	Solute carrier family 17 member 8. (571 aa)
	ADCY8	Adenylate cyclase 8. (1238 aa)
	NLGN4X	Neuroligin-4, X-linked isoform X1. (836 aa)
	NLGN3	Neuroligin-3 isoform X1. (833 aa)
	GRIA3	Glutamate receptor 3 isoform X1. (888 aa)
	IGSF11	Immunoglobulin superfamily member 11 isoform X1. (468 aa)
	SYT11	Synaptotagmin-11. (427 aa)
	SLC17A6	Vesicular glutamate transporter 2. (581 aa)
	GRIA1	Glutamate receptor 1 isoform X1. (902 aa)
	LRRTM2	Leucine-rich repeat transmembrane neuronal protein 2 isoform X1. (383 aa)
	ITGA3	Integrin subunit alpha 3. (1027 aa)
	CNTN6	Contactin-6 isoform X1. (1038 aa)
	KCNJ3	Potassium inwardly-rectifying channel subfamily J member 3. (493 aa)
	LOC107199497	Neuroligin-2-like. (414 aa)
	SYNDIG1	Synapse differentiation-inducing gene protein 1. (258 aa)
	NLGN1	Neuroligin-1 isoform X1. (863 aa)
	SYNJ1	Synaptojanin-1 isoform X1. (1553 aa)
	LOC107215186	G protein-activated inward rectifier potassium channel 1-like. (479 aa)
	PPP3R1	Serine/threonine-protein phosphatase 2B regulatory subunit. (254 aa)
	AKAP5	A-kinase anchoring protein 5. (411 aa)
	BAIAP2	Brain-specific angiogenesis inhibitor 1-associated protein 2 isoform X1. (575 aa)
	CYFIP1	Cytoplasmic FMR1-interacting protein 1 isoform X1. (1334 aa)
	P2RX6	P2X purinoceptor 6 isoform X1. (373 aa)

Your Current Organism:

Parus major

NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKAP5	GRIA1	ENSPMJP00000001819	ENSPMJP00000009829	A-kinase anchoring protein 5.	Glutamate receptor 1 isoform X1.	0.433
BAIAP2	CYFIP1	ENSPMJP00000023025	ENSPMJP00000022081	Brain-specific angiogenesis inhibitor 1-associated protein 2 isoform X1.	Cytoplasmic FMR1-interacting protein 1 isoform X1.	0.754
CYFIP1	BAIAP2	ENSPMJP00000022081	ENSPMJP00000023025	Cytoplasmic FMR1-interacting protein 1 isoform X1.	Brain-specific angiogenesis inhibitor 1-associated protein 2 isoform X1.	0.754
GRIA1	AKAP5	ENSPMJP00000009829	ENSPMJP00000001819	Glutamate receptor 1 isoform X1.	A-kinase anchoring protein 5.	0.433
GRIA1	GRIA3	ENSPMJP00000009829	ENSPMJP00000015006	Glutamate receptor 1 isoform X1.	Glutamate receptor 3 isoform X1.	0.955
GRIA3	GRIA1	ENSPMJP00000015006	ENSPMJP00000009829	Glutamate receptor 3 isoform X1.	Glutamate receptor 1 isoform X1.	0.955
NLGN1	NLGN3	ENSPMJP00000003445	ENSPMJP00000015139	Neuroligin-1 isoform X1.	Neuroligin-3 isoform X1.	0.907
NLGN1	NLGN4X	ENSPMJP00000003445	ENSPMJP00000015234	Neuroligin-1 isoform X1.	Neuroligin-4, X-linked isoform X1.	0.907
NLGN3	NLGN1	ENSPMJP00000015139	ENSPMJP00000003445	Neuroligin-3 isoform X1.	Neuroligin-1 isoform X1.	0.907
NLGN3	NLGN4X	ENSPMJP00000015139	ENSPMJP00000015234	Neuroligin-3 isoform X1.	Neuroligin-4, X-linked isoform X1.	0.909
NLGN4X	NLGN1	ENSPMJP00000015234	ENSPMJP00000003445	Neuroligin-4, X-linked isoform X1.	Neuroligin-1 isoform X1.	0.907
NLGN4X	NLGN3	ENSPMJP00000015234	ENSPMJP00000015139	Neuroligin-4, X-linked isoform X1.	Neuroligin-3 isoform X1.	0.909