(24 nodes) Regulation of sprouting angiogenesis network (Ornithorhynchus anatinus)

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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Predicted Interactions

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Your Input:
	TNN	Tenascin N. (1418 aa)
	GLUL	Glutamine synthetase. (373 aa)
	PDPK1	Protein kinase domain-containing protein. (280 aa)
	SYNJ2BP	PDZ domain-containing protein. (125 aa)
	THBS1	Thrombospondin 1. (902 aa)
	F6X7F6_ORNAN	Uncharacterized protein. (444 aa)
	CEMIP2	Cell migration inducing hyaluronidase 2. (1272 aa)
	BMPER	Uncharacterized protein. (507 aa)
	SMAD1	Mothers against decapentaplegic homolog. (465 aa)
	ITGA5	Integrin_alpha2 domain-containing protein. (543 aa)
	LOC100093029	Glutamine synthetase. (383 aa)
	SEMA6A	Semaphorin 6A; Belongs to the semaphorin family. (960 aa)
	F7G762_ORNAN	Uncharacterized protein. (158 aa)
	IL10	Interleukin 10. (181 aa)
	FUT2	L-Fucosyltransferase; Belongs to the glycosyltransferase 11 family. (351 aa)
	FGF1	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
	PIK3CB	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1034 aa)
	F7CK33_ORNAN	E2F_TDP domain-containing protein. (460 aa)
	F6W2G5_ORNAN	Uncharacterized protein. (437 aa)
	EPN2	Epsin 2. (583 aa)
	JAK1	Protein kinase domain-containing protein. (107 aa)
	ALOX5	Lipoxygenase domain-containing protein. (110 aa)
	DLL1	EGF-like domain-containing protein. (52 aa)
	K7EHC9_ORNAN	L-Fucosyltransferase; Belongs to the glycosyltransferase 11 family. (450 aa)

Your Current Organism:

Ornithorhynchus anatinus

NCBI taxonomy Id: 9258
Other names: O. anatinus, Platypus anatinus, duck-billed platypus, duckbill platypus, platypus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F7G762_ORNAN	PDPK1	ENSOANP00000014480	ENSOANP00000003693	Uncharacterized protein.	Protein kinase domain-containing protein.	0.461
FGF1	PIK3CB	ENSOANP00000022448	ENSOANP00000023160	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...]	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.476
GLUL	LOC100093029	ENSOANP00000001548	ENSOANP00000012859	Glutamine synthetase.	Glutamine synthetase.	0.901
IL10	JAK1	ENSOANP00000015289	ENSOANP00000026615	Interleukin 10.	Protein kinase domain-containing protein.	0.751
ITGA5	TNN	ENSOANP00000012732	ENSOANP00000001457	Integrin_alpha2 domain-containing protein.	Tenascin N.	0.768
JAK1	IL10	ENSOANP00000026615	ENSOANP00000015289	Protein kinase domain-containing protein.	Interleukin 10.	0.751
JAK1	PIK3CB	ENSOANP00000026615	ENSOANP00000023160	Protein kinase domain-containing protein.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.936
LOC100093029	GLUL	ENSOANP00000012859	ENSOANP00000001548	Glutamine synthetase.	Glutamine synthetase.	0.901
PDPK1	F7G762_ORNAN	ENSOANP00000003693	ENSOANP00000014480	Protein kinase domain-containing protein.	Uncharacterized protein.	0.461
PDPK1	PIK3CB	ENSOANP00000003693	ENSOANP00000023160	Protein kinase domain-containing protein.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.957
PIK3CB	FGF1	ENSOANP00000023160	ENSOANP00000022448	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...]	0.476
PIK3CB	JAK1	ENSOANP00000023160	ENSOANP00000026615	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	Protein kinase domain-containing protein.	0.936
PIK3CB	PDPK1	ENSOANP00000023160	ENSOANP00000003693	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	Protein kinase domain-containing protein.	0.957
TNN	ITGA5	ENSOANP00000001457	ENSOANP00000012732	Tenascin N.	Integrin_alpha2 domain-containing protein.	0.768