(26 nodes) Rossmann-like alpha/beta/alpha sandwich fold network (Sarcophilus harrisii)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	IARS2	Isoleucyl-tRNA synthetase 2, mitochondrial. (1019 aa)
	LARS1	Leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (1177 aa)
	PAPSS2	3'-phosphoadenosine 5'-phosphosulfate synthase 2. (612 aa)
	ASS1	Argininosuccinate synthase 1. (415 aa)
	VARS1	Valyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (1268 aa)
	QARS1	Glutaminyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (738 aa)
	CRY1	Cryptochrome circadian regulator 1. (557 aa)
	WARS1	Tryptophanyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (476 aa)
	WARS2	Tryptophanyl tRNA synthetase 2, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family. (362 aa)
	NMNAT3	Nicotinamide-nucleotide adenylyltransferase. (246 aa)
	ASNSD1	Asparagine synthetase domain-containing protein. (635 aa)
	YARS1	Tyrosine--tRNA ligase. (528 aa)
	RARS2	Arginyl-tRNA synthetase 2, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family. (479 aa)
	GMPS	Guanine monophosphate synthase. (693 aa)
	PCYT2	Phosphate cytidylyltransferase 2, ethanolamine. (370 aa)
	VARS2	Valyl-tRNA synthetase 2, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family. (1056 aa)
	PAPSS1	3'-phosphoadenosine 5'-phosphosulfate synthase 1. (624 aa)
	NADSYN1	Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family. (678 aa)
	IARS1	Isoleucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (1222 aa)
	EPRS1	Glutamyl-prolyl-tRNA synthetase. (1450 aa)
	MARS2	Methionyl-tRNA synthetase 2, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family. (548 aa)
	RARS1	Arginyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (661 aa)
	CTU2	Cytoplasmic tRNA 2-thiolation protein 2; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with CTU1/ATPBD3 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Belongs to the CTU2/NCS2 family. (513 aa)
	MARS1	Methionyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (899 aa)
	CARS1	Cysteinyl-tRNA synthetase. (838 aa)
	YARS2	Tyrosine--tRNA ligase. (478 aa)

Your Current Organism:

Sarcophilus harrisii

NCBI taxonomy Id: 9305
Other names: S. harrisii, Sarcophilus laniarius, Tasmanian devil

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASNSD1	ASS1	ENSSHAP00000014263	ENSSHAP00000017854	Asparagine synthetase domain-containing protein.	Argininosuccinate synthase 1.	0.596
ASNSD1	CARS1	ENSSHAP00000014263	ENSSHAP00000003664	Asparagine synthetase domain-containing protein.	Cysteinyl-tRNA synthetase.	0.507
ASNSD1	EPRS1	ENSSHAP00000014263	ENSSHAP00000002702	Asparagine synthetase domain-containing protein.	Glutamyl-prolyl-tRNA synthetase.	0.626
ASNSD1	GMPS	ENSSHAP00000014263	ENSSHAP00000012067	Asparagine synthetase domain-containing protein.	Guanine monophosphate synthase.	0.725
ASNSD1	MARS1	ENSSHAP00000014263	ENSSHAP00000008287	Asparagine synthetase domain-containing protein.	Methionyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.	0.435
ASNSD1	NADSYN1	ENSSHAP00000014263	ENSSHAP00000008619	Asparagine synthetase domain-containing protein.	Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family.	0.504
ASNSD1	QARS1	ENSSHAP00000014263	ENSSHAP00000017745	Asparagine synthetase domain-containing protein.	Glutaminyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.	0.426
ASNSD1	VARS1	ENSSHAP00000014263	ENSSHAP00000007995	Asparagine synthetase domain-containing protein.	Valyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.	0.575
ASNSD1	YARS1	ENSSHAP00000014263	ENSSHAP00000013859	Asparagine synthetase domain-containing protein.	Tyrosine--tRNA ligase.	0.747
ASS1	ASNSD1	ENSSHAP00000017854	ENSSHAP00000014263	Argininosuccinate synthase 1.	Asparagine synthetase domain-containing protein.	0.596
ASS1	EPRS1	ENSSHAP00000017854	ENSSHAP00000002702	Argininosuccinate synthase 1.	Glutamyl-prolyl-tRNA synthetase.	0.488
ASS1	VARS1	ENSSHAP00000017854	ENSSHAP00000007995	Argininosuccinate synthase 1.	Valyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.	0.434
CARS1	ASNSD1	ENSSHAP00000003664	ENSSHAP00000014263	Cysteinyl-tRNA synthetase.	Asparagine synthetase domain-containing protein.	0.507
CARS1	EPRS1	ENSSHAP00000003664	ENSSHAP00000002702	Cysteinyl-tRNA synthetase.	Glutamyl-prolyl-tRNA synthetase.	0.830
CARS1	GMPS	ENSSHAP00000003664	ENSSHAP00000012067	Cysteinyl-tRNA synthetase.	Guanine monophosphate synthase.	0.529
CARS1	IARS1	ENSSHAP00000003664	ENSSHAP00000000272	Cysteinyl-tRNA synthetase.	Isoleucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.	0.593
CARS1	IARS2	ENSSHAP00000003664	ENSSHAP00000005452	Cysteinyl-tRNA synthetase.	Isoleucyl-tRNA synthetase 2, mitochondrial.	0.599
CARS1	LARS1	ENSSHAP00000003664	ENSSHAP00000007000	Cysteinyl-tRNA synthetase.	Leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.	0.759
CARS1	MARS1	ENSSHAP00000003664	ENSSHAP00000008287	Cysteinyl-tRNA synthetase.	Methionyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.	0.820
CARS1	MARS2	ENSSHAP00000003664	ENSSHAP00000021209	Cysteinyl-tRNA synthetase.	Methionyl-tRNA synthetase 2, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family.	0.559