(13 nodes) Auditory receptor cell stereocilium organization network (Erinaceus europaeus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RIPOR2	Protein FAM65B isoform X1. (1063 aa)
	TPRN	Taperin isoform X2. (418 aa)
	PLS1	Plastin-1 isoform X1. (626 aa)
	STRC	Stereocilin. (1762 aa)
	LHFPL5	Tetraspan membrane protein of hair cell stereocilia isoform X2. (219 aa)
	LRRC1	Leucine-rich repeat-containing protein 1. (522 aa)
	PDZD7	PDZ domain-containing protein 7. (288 aa)
	SEC24B	Protein transport protein Sec24B. (1210 aa)
	ENSEEUP00000007375	annotation not available (248 aa)
	CLRN2	Clarin-2. (232 aa)
	WHRN	Whirlin isoform X2. (901 aa)
	SCRIB	Protein scribble homolog isoform X1. (1630 aa)
	CLRN1	Clarin 1. (232 aa)

Your Current Organism:

Erinaceus europaeus

NCBI taxonomy Id: 9365
Other names: E. europaeus, European hedgehog, common hedgehog, western European hedgehog

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CLRN1	ENSEEUP00000007375	ENSEEUP00000011971	ENSEEUP00000007375	Clarin 1.	annotation not available	0.412
CLRN1	LHFPL5	ENSEEUP00000011971	ENSEEUP00000001683	Clarin 1.	Tetraspan membrane protein of hair cell stereocilia isoform X2.	0.510
CLRN1	PDZD7	ENSEEUP00000011971	ENSEEUP00000004253	Clarin 1.	PDZ domain-containing protein 7.	0.682
CLRN1	STRC	ENSEEUP00000011971	ENSEEUP00000001525	Clarin 1.	Stereocilin.	0.530
CLRN1	WHRN	ENSEEUP00000011971	ENSEEUP00000010471	Clarin 1.	Whirlin isoform X2.	0.758
CLRN2	ENSEEUP00000007375	ENSEEUP00000008195	ENSEEUP00000007375	Clarin-2.	annotation not available	0.613
CLRN2	STRC	ENSEEUP00000008195	ENSEEUP00000001525	Clarin-2.	Stereocilin.	0.497
ENSEEUP00000007375	CLRN1	ENSEEUP00000007375	ENSEEUP00000011971	annotation not available	Clarin 1.	0.412
ENSEEUP00000007375	CLRN2	ENSEEUP00000007375	ENSEEUP00000008195	annotation not available	Clarin-2.	0.613
ENSEEUP00000007375	PDZD7	ENSEEUP00000007375	ENSEEUP00000004253	annotation not available	PDZ domain-containing protein 7.	0.514
ENSEEUP00000007375	PLS1	ENSEEUP00000007375	ENSEEUP00000001420	annotation not available	Plastin-1 isoform X1.	0.622
ENSEEUP00000007375	RIPOR2	ENSEEUP00000007375	ENSEEUP00000013910	annotation not available	Protein FAM65B isoform X1.	0.791
ENSEEUP00000007375	STRC	ENSEEUP00000007375	ENSEEUP00000001525	annotation not available	Stereocilin.	0.767
ENSEEUP00000007375	TPRN	ENSEEUP00000007375	ENSEEUP00000000799	annotation not available	Taperin isoform X2.	0.697
ENSEEUP00000007375	WHRN	ENSEEUP00000007375	ENSEEUP00000010471	annotation not available	Whirlin isoform X2.	0.633
LHFPL5	CLRN1	ENSEEUP00000001683	ENSEEUP00000011971	Tetraspan membrane protein of hair cell stereocilia isoform X2.	Clarin 1.	0.510
LHFPL5	PDZD7	ENSEEUP00000001683	ENSEEUP00000004253	Tetraspan membrane protein of hair cell stereocilia isoform X2.	PDZ domain-containing protein 7.	0.504
LHFPL5	STRC	ENSEEUP00000001683	ENSEEUP00000001525	Tetraspan membrane protein of hair cell stereocilia isoform X2.	Stereocilin.	0.547
LHFPL5	WHRN	ENSEEUP00000001683	ENSEEUP00000010471	Tetraspan membrane protein of hair cell stereocilia isoform X2.	Whirlin isoform X2.	0.485
PDZD7	CLRN1	ENSEEUP00000004253	ENSEEUP00000011971	PDZ domain-containing protein 7.	Clarin 1.	0.682