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EHQ36810.1 EHQ36810.1 EHQ36991.1 EHQ36991.1 EHQ36892.1 EHQ36892.1 EHQ36868.1 EHQ36868.1 EHQ36859.1 EHQ36859.1 EHQ36851.1 EHQ36851.1 EHQ36842.1 EHQ36842.1 EHQ36834.1 EHQ36834.1 dacZ dacZ EHQ36715.1 EHQ36715.1 EHQ36613.1 EHQ36613.1 thiI-2 thiI-2 EHQ36312.1 EHQ36312.1 rpoA2 rpoA2 EHQ35866.1 EHQ35866.1 EHQ35865.1 EHQ35865.1 EHQ35864.1 EHQ35864.1 rpoH rpoH priS priS EHQ35790.1 EHQ35790.1 mobA mobA EHQ35676.1 EHQ35676.1 EHQ35621.1 EHQ35621.1 polB polB EHQ35443.1 EHQ35443.1 EHQ35320.1 EHQ35320.1 EHQ35068.1 EHQ35068.1 polC polC EHQ35019.1 EHQ35019.1 ribL ribL EHQ34928.1 EHQ34928.1 EHQ34927.1 EHQ34927.1 EHQ34924.1 EHQ34924.1 dbh dbh cofC cofC rpoD rpoD rpoN rpoN EHQ34817.1 EHQ34817.1 EHQ34714.1 EHQ34714.1 EHQ34660.1 EHQ34660.1 rpoP rpoP thiI thiI EHQ34451.1 EHQ34451.1 EHQ34436.1 EHQ34436.1 carS carS dnaG dnaG priL priL cca cca EHQ34205.1 EHQ34205.1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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co-expression
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EHQ36810.1Galactose-1-phosphate uridylyltransferase-like protein; COGs: COG1085 Galactose-1-phosphate uridylyltransferase; KEGG: mpi:Mpet_2181 galactose-1-phosphate uridylyltransferase-like protein; SPTR: Galactose-1-phosphate uridylyltransferase-like protein. (309 aa)
EHQ36991.1DNA polymerase beta domain protein region; PFAM: Nucleotidyltransferase domain; InterPro IPR002934; KEGG: nucleotidyltransferase; PFAM: Nucleotidyltransferase; SPTR: DNA polymerase beta domain protein region. (101 aa)
EHQ36892.1DNA polymerase beta domain protein region; PFAM: Nucleotidyltransferase domain; InterPro IPR002934; KEGG: mhu:Mhun_3062 DNA polymerase, beta-like region; PFAM: Nucleotidyltransferase; SPTR: DNA polymerase, beta-like region. (115 aa)
EHQ36868.1PFAM: Cytidylyltransferase; TIGRFAM: 3-deoxy-D-manno-octulosonate cytidylyltransferase; COGs: COG1212 CMP-2-keto-3-deoxyoctulosonic acid synthetase; HAMAP: 3-deoxy-D-manno-octulosonate cytidylyltransferase; InterPro IPR003329:IPR004528; KEGG: sku:Sulku_2393 3-deoxy-D-manno-octulosonatecytidylyltransferase; PFAM: Acylneuraminate cytidylyltransferase; SPTR:3-deoxy-D-manno-octulosonatecytidylyltransfera se; TIGRFAM: 3-deoxy-D-manno-octulosonate cytidylyltransferase. (249 aa)
EHQ36859.1PFAM: Nucleotidyl transferase; TIGRFAM: glucose-1-phosphate thymidylylransferase, long form; COGs: COG1209 dTDP-glucose pyrophosphorylase; InterPro IPR005835:IPR001451:IPR005908; KEGG: ton:TON_1842 nucleotidyltransferase; PFAM: Nucleotidyl transferase; Bacterial transferase hexapeptide repeat; SPTR: Glucose-1-phosphate thymidylyltransferase; TIGRFAM: Glucose-1-phosphate thymidylyltransferase, short form. (353 aa)
EHQ36851.1PFAM: Cytidylyltransferase; COGs: COG1083 CMP-N-acetylneuraminic acid synthetase; InterPro IPR003329; KEGG: atm:ANT_06460 putative N-acylneuraminate cytidylyltransferase; PFAM: Acylneuraminate cytidylyltransferase; SPTR: Putative N-acylneuraminate cytidylyltransferase. (242 aa)
EHQ36842.1PFAM: Nucleotidyl transferase; COGs: COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon); InterPro IPR005835; KEGG: mbu:Mbur_1584 nucleotidyl transferase; PFAM: Nucleotidyl transferase; SPTR: Mannose-1-phosphate guanyltransferase. (234 aa)
EHQ36834.1PFAM: Cytidylyltransferase; TIGRFAM: nicotinamide-nucleotide adenylyltransferase; cytidyltransferase-related domain; COGs: COG1056 Nicotinamide mononucleotide adenylyltransferase; HAMAP: Nicotinamide-nucleotide adenylyltransferase, archaeal type; InterPro IPR004820:IPR006418:IPR004821; KEGG: mpi:Mpet_2371 nicotinamide-nucleotide adenylyltransferase; PFAM: Cytidylyltransferase; SPTR: Nicotinamide-nucleotide adenylyltransferase; TIGRFAM: Nicotinamide-nucleotide adenylyltransferase, archaeal type; Cytidyltransferase-related. (169 aa)
dacZProtein of unknown function DUF147; Diadenylate cyclase that catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP is a second messenger for intracellular signal transduction involved in the control of important regulatory processes such as osmoregulation. (261 aa)
EHQ36715.1COGs: COG1665 conserved hypothetical protein; KEGG: mpi:Mpet_1977 hypothetical protein; SPTR: Putative uncharacterized protein. (309 aa)
EHQ36613.1tRNA(His)-5'-guanylyltransferase; PFAM: tRNAHis guanylyltransferase; COGs: COG4021 conserved hypothetical protein; InterPro IPR007537; KEGG: mpi:Mpet_2135 hypothetical protein; PFAM: tRNAHis guanylyltransferase; SPTR: Putative uncharacterized protein. (247 aa)
thiI-2tRNA sulfurtransferase; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (397 aa)
EHQ36312.1DNA polymerase beta domain protein region; PFAM: Nucleotidyltransferase domain; COGs: COG1669 nucleotidyltransferase; InterPro IPR002934; KEGG: mpi:Mpet_0445 DNA polymerase beta domain-containing protein; PFAM: Nucleotidyltransferase; SPTR: DNA polymerase beta domain protein region. (143 aa)
rpoA2DNA-directed RNA polymerase, subunit A; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (388 aa)
EHQ35866.1DNA-directed RNA polymerase, subunit A; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (881 aa)
EHQ35865.1DNA-directed RNA polymerase, subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (609 aa)
EHQ35864.1DNA-directed RNA polymerase, subunit B; PFAM: RNA polymerase Rpb2, domain 3; RNA polymerase Rpb2, domain 2; RNA polymerase beta subunit; COGs: COG0085 DNA-directed RNA polymerase beta subunit/140 kD subunit; InterPro IPR007644:IPR007642:IPR007645; KEGG: mpi:Mpet_1737 DNA-directed RNA polymerase; PFAM: RNA polymerase, beta subunit, protrusion; RNA polymerase Rpb2, domain 2; RNA polymerase Rpb2, domain 3; SPTR: DNA-directed RNA polymerase; overlaps another CDS with the same product name. (518 aa)
rpoHDNA-directed RNA polymerase, subunit H; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family. (91 aa)
priSDNA primase small subunit; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. [...] (380 aa)
EHQ35790.1PFAM: Nucleotidyl transferase; TIGRFAM: glucose-1-phosphate thymidylylransferase, long form; COGs: COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon); InterPro IPR005835:IPR001451; KEGG: mpi:Mpet_1827 nucleotidyl transferase; PFAM: Nucleotidyl transferase; Bacterial transferase hexapeptide repeat; SPTR: Nucleotidyl transferase. (392 aa)
mobAMolybdopterin-guanine dinucleotide biosynthesis protein A; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor. (209 aa)
EHQ35676.1PFAM: DNA polymerase family B; DNA polymerase family B, exonuclease domain; COGs: COG0417 DNA polymerase elongation subunit (family B); InterPro IPR006172:IPR006133:IPR006134; KEGG: mpi:Mpet_1929 DNA polymerase B region; PFAM: DNA-directed DNA polymerase, family B, conserved region; DNA-directed DNA polymerase, family B, exonuclease domain; SMART: DNA-directed DNA polymerase, family B; SPTR: DNA polymerase. (843 aa)
EHQ35621.1PFAM: Probable molybdopterin binding domain; TIGRFAM: molybdenum cofactor synthesis domain; COGs: COG0521 Molybdopterin biosynthesis protein; InterPro IPR020817:IPR001453; KEGG: mpi:Mpet_1413 molybdenum cofactor synthesis domain-containing protein; PFAM: Molybdopterin binding; SPTR: Molybdenum cofactor synthesis domain protein; TIGRFAM: Molybdenum cofactor synthesis. (167 aa)
polBDNA polymerase II small subunit; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase; Belongs to the DNA polymerase delta/II small subunit family. (497 aa)
EHQ35443.1PFAM: Nucleotidyl transferase; TIGRFAM: glucose-1-phosphate thymidylylransferase, long form; glucose-1-phosphate thymidylyltransferase, short form; COGs: COG1209 dTDP-glucose pyrophosphorylase; InterPro IPR005835; KEGG: mhu:Mhun_3107 nucleotidyl transferase; PFAM: Nucleotidyl transferase; SPTR: Nucleotidyl transferase. (252 aa)
EHQ35320.1DNA-directed RNA polymerase, subunit E; PFAM: S1 RNA binding domain; RNA polymerase Rpb7-like, N-terminal domain; TIGRFAM: DNA-directed RNA polymerase (rpoE), archaeal and eukaryotic form; COGs: COG1095 DNA-directed RNA polymerase subunit E'; InterPro IPR005576:IPR003029:IPR004519; KEGG: mpi:Mpet_0091 DNA-directed RNA polymerase; PFAM: RNA polymerase Rpb7, N-terminal; Ribosomal protein S1, RNA binding domain; SPTR: DNA-directed RNA polymerase; TIGRFAM: DNA-directed RNA polymerase. (190 aa)
EHQ35068.1DNA polymerase beta domain protein region; PFAM: Nucleotidyltransferase domain; COGs: COG1669 nucleotidyltransferase; InterPro IPR002934; KEGG: mbn:Mboo_0374 DNA polymerase beta subunit; PFAM: Nucleotidyltransferase; SPTR: DNA polymerase, beta domain protein region. (93 aa)
polCDNA polymerase II large subunit; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase. (1299 aa)
EHQ35019.1RNA polymerase; COGs: COG1761 DNA-directed RNA polymerase subunit L; KEGG: mpi:Mpet_0583 RNA polymerase; SPTR: RNA polymerase, dimerization. (89 aa)
ribLFMN adenylyltransferase; Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme. (144 aa)
EHQ34928.1PFAM: Nucleotidyl transferase; Bacterial transferase hexapeptide (three repeats); TIGRFAM: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; glucose-1-phosphate thymidylylransferase, long form; COGs: COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon); InterPro IPR005835:IPR001451; KEGG: mem:Memar_2229 nucleotidyl transferase; PFAM: Nucleotidyl transferase; Bacterial transferase hexapeptide repeat; SPTR: Nucleotidyl transferase. (400 aa)
EHQ34927.1PFAM: Nucleotidyl transferase; TIGRFAM: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; COGs: COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon); InterPro IPR005835:IPR001451; KEGG: mem:Memar_2230 nucleotidyl transferase; PFAM: Nucleotidyl transferase; Bacterial transferase hexapeptide repeat; SPTR: Nucleotidyl transferase. (383 aa)
EHQ34924.1UDP-glucose pyrophosphorylase; PFAM: Nucleotidyl transferase; TIGRFAM: UTP-glucose-1-phosphate uridylyltransferase; COGs: COG1210 UDP-glucose pyrophosphorylase; InterPro IPR005835:IPR005771; KEGG: mbu:Mbur_1612 UDP-glucose pyrophosphorylase; PFAM: Nucleotidyl transferase; SPTR: UTP--glucose-1-phosphate uridylyltransferase; TIGRFAM: UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal type. (289 aa)
dbhDNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis. (364 aa)
cofCPhospholactate guanylyltransferase; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor; Belongs to the CofC family. (212 aa)
rpoDDNA-directed RNA polymerase, subunit D; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (274 aa)
rpoNDNA-directed RNA polymerase, subunit N; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoN/eukaryotic RPB10 RNA polymerase subunit family. (62 aa)
EHQ34817.1DNA-directed RNA polymerase, subunit K; PFAM: RNA polymerase Rpb6; InterPro IPR006110; KEGG: mpi:Mpet_0756 RNA polymerase Rpb6; PFAM: RNA polymerase Rpb6; SPTR: RNA polymerase Rpb6. (55 aa)
EHQ34714.1PFAM: Nucleotidyl transferase; Mannose-6-phosphate isomerase; TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; COGs: COG0836 Mannose-1-phosphate guanylyltransferase; InterPro IPR006375:IPR005835:IPR001538; KEGG: mpi:Mpet_0839 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: Mannose-6-phosphate isomerase, type II, C-terminal; Nucleotidyl transferase; SPTR: Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; TIGRFAM: Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; Belongs to the mannose-6 [...] (448 aa)
EHQ34660.1PFAM: Cytidylyltransferase; TIGRFAM: cytidyltransferase-related domain; COGs: COG1019 nucleotidyltransferase; InterPro IPR004821:IPR004820; KEGG: mpi:Mpet_0931 cytidyltransferase-like domain-containing protein; PFAM: Cytidylyltransferase; SPTR: Cytidyltransferase-related domain protein; TIGRFAM: Cytidyltransferase-related. (154 aa)
rpoPDNA-directed RNA polymerase, subunit P; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoP/eukaryotic RPC10 RNA polymerase subunit family. (43 aa)
thiItRNA sulfurtransferase; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (396 aa)
EHQ34451.1DNA polymerase beta domain protein region; PFAM: Nucleotidyltransferase domain; COGs: COG1669 nucleotidyltransferase; InterPro IPR002934; KEGG: srm:SRM_00813 conserved hypothetical protein containing nucleotidyltransferase domain; PFAM: Nucleotidyltransferase; SPTR: Putative uncharacterized protein. (106 aa)
EHQ34436.1DNA polymerase beta domain protein region; PFAM: Nucleotidyltransferase domain; InterPro IPR002934; KEGG: mem:Memar_0170 DNA polymerase beta subunit; PFAM: Nucleotidyltransferase; SPTR: DNA polymerase, beta domain protein region. (114 aa)
carSUPF0290 protein; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids. (184 aa)
dnaGUPF0095 protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (403 aa)
priLDNA primase large subunit; Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair. (381 aa)
ccatRNA adenylyltransferase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. (458 aa)
EHQ34205.1DNA polymerase beta domain protein region; PFAM: Nucleotidyltransferase domain; COGs: COG1669 nucleotidyltransferase; InterPro IPR002934; KEGG: mac:MA0100 nucleotidyltransferase; PFAM: Nucleotidyltransferase; SPTR: Nucleotidyltransferase. (107 aa)
Your Current Organism:
Methanoplanus limicola
NCBI taxonomy Id: 937775
Other names: M. limicola DSM 2279, Methanoplanus limicola DSM 2279, Methanoplanus limicola str. DSM 2279, Methanoplanus limicola strain DSM 2279
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