STRINGSTRING
PTSG_00885 PTSG_00885 PTSG_01473 PTSG_01473 PTSG_02165 PTSG_02165 PTSG_02255 PTSG_02255 PTSG_02275 PTSG_02275 PTSG_02325 PTSG_02325 PTSG_03233 PTSG_03233 PTSG_03534 PTSG_03534 PTSG_04131 PTSG_04131 PTSG_04413 PTSG_04413 PTSG_04464 PTSG_04464 PTSG_05500 PTSG_05500 PTSG_05872 PTSG_05872 PTSG_05890 PTSG_05890 PTSG_12562 PTSG_12562 PTSG_06881 PTSG_06881 PTSG_07586 PTSG_07586 PTSG_08200 PTSG_08200 PTSG_08382 PTSG_08382 PTSG_08893 PTSG_08893 PTSG_09520 PTSG_09520 PTSG_09116 PTSG_09116 PTSG_12968 PTSG_12968 PTSG_10723 PTSG_10723 PTSG_11066 PTSG_11066
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PTSG_00885Citrate synthase; Belongs to the citrate synthase family. (458 aa)
PTSG_01473Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (455 aa)
PTSG_02165Cytosolic malate dehydrogenase; Belongs to the LDH/MDH superfamily. (335 aa)
PTSG_02255Succinate dehydrogenase [ubiquinone] cytochrome b small subunit. (152 aa)
PTSG_02275Succinate-CoA ligase subunit beta. (420 aa)
PTSG_02325Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (358 aa)
PTSG_03233Phosphoenolpyruvate carboxykinase. (561 aa)
PTSG_03534Transket_pyr domain-containing protein. (1083 aa)
PTSG_04131Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (322 aa)
PTSG_04413Isocitrate dehydrogenase. (336 aa)
PTSG_04464Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (380 aa)
PTSG_05500Fumarate hydratase. (506 aa)
PTSG_05872Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (645 aa)
PTSG_05890Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (423 aa)
PTSG_12562Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1145 aa)
PTSG_06881Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (262 aa)
PTSG_07586Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (368 aa)
PTSG_08200Fumarate hydratase class I. (581 aa)
PTSG_08382Dihydrolipoyl dehydrogenase. (506 aa)
PTSG_088932-oxoglutarate dehydrogenase. (1019 aa)
PTSG_09520ATP-citrate synthase; In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family. (1083 aa)
PTSG_09116Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (780 aa)
PTSG_12968Dihydrolipoamide S-succinyltransferase. (442 aa)
PTSG_10723Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (353 aa)
PTSG_11066Malate dehydrogenase. (343 aa)
Your Current Organism:
Salpingoeca rosetta
NCBI taxonomy Id: 946362
Other names: Proterospongia sp. ATCC 50818, S. rosetta, Salpingoeca rosetta ATCC 50818, Salpingoeca rosetta ATCC50818, Salpingoeca rosetta Dayel et al. 2011, Salpingoeca sp. ATCC 50818, Salpingoeca sp. ATCC50818
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