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IDO1 IDO1 MB MB HMOX1 HMOX1 CYP24A1 CYP24A1 HCCS HCCS CYP19A1 CYP19A1 CYP8B1 CYP8B1 GUCY1A1 GUCY1A1 CYP21A2 CYP21A2 DUOX1 DUOX1 LOC100415600 LOC100415600 CYP2D19 CYP2D19 C1orf194 C1orf194 CCNDBP1 CCNDBP1 CYB561D1 CYB561D1 RTTN RTTN CYP26B1 CYP26B1 SDHC SDHC CYP2E1 CYP2E1 CYB561D2 CYB561D2 CYBB CYBB PTGS2 PTGS2 SUOX SUOX IDO2 IDO2 CYP27B1 CYP27B1 CYP46A1 CYP46A1 TTI2 TTI2 CYP26C1 CYP26C1 CYP26A1 CYP26A1 NOS1 NOS1 CYP2R1 CYP2R1 GUCY1A2 GUCY1A2 CYP27C1 CYP27C1 DGCR8 DGCR8 SDHD SDHD CYP27A1 CYP27A1 TPO TPO HBM HBM F6RYT9_CALJA F6RYT9_CALJA CYB5D2 CYB5D2 NOS2 NOS2 TBXAS1 TBXAS1 CYGB CYGB CYP51A1 CYP51A1 FA2H FA2H HRG HRG PXDNL PXDNL CYP2F1 CYP2F1 SLC48A1 SLC48A1 FLVCR1 FLVCR1 CYP3A5 CYP3A5 CYP2W1 CYP2W1 CYP2C76 CYP2C76 NR1D1 NR1D1 CYP2J2 CYP2J2 F7I7J6_CALJA F7I7J6_CALJA LOC100410987 LOC100410987 EPX EPX LPO LPO MPO MPO CYP1A1 CYP1A1 CYP1A2 CYP1A2 CYP17A1 CYP17A1 RSAD1 RSAD1 ADGB ADGB CYP2U1 CYP2U1 F7B0K7_CALJA F7B0K7_CALJA CYP2B6 CYP2B6 CYP2S1 CYP2S1 ENSCJAP00000037571 ENSCJAP00000037571 NOS3 NOS3 CYP4V2 CYP4V2 KLKB1 KLKB1 FLVCR2 FLVCR2 CYP4A11 CYP4A11 CYP4Z1 CYP4Z1 CYC1 CYC1 CYP11B1 CYP11B1 HEBP1 HEBP1 PTGS1 PTGS1 F6TTF3_CALJA F6TTF3_CALJA JAK2 JAK2 CYP2C8 CYP2C8 CYP3A21 CYP3A21 ABCB6 ABCB6 BTBD6 BTBD6 THAP4 THAP4 GUCY1B1 GUCY1B1 HBQ1_1 HBQ1_1 BACH1 BACH1 STEAP4 STEAP4 ENSCJAP00000054842 ENSCJAP00000054842 CYP1B1 CYP1B1 ENSCJAP00000055709 ENSCJAP00000055709 LOC100413276 LOC100413276 HEBP2 HEBP2 B3GNT8 B3GNT8 NGB NGB CYB5R4 CYB5R4 LOC100406761 LOC100406761 PTGIS PTGIS PGRMC1 PGRMC1 CYP4X1 CYP4X1 LOC100401718 LOC100401718 ENSCJAP00000061810 ENSCJAP00000061810 LOC108593648 LOC108593648 CYP20A1 CYP20A1 CCDC160 CCDC160 PGRMC2 PGRMC2 ENSCJAP00000068039 ENSCJAP00000068039 CYP11A1 CYP11A1 CYP4F2 CYP4F2 ENSCJAP00000069747 ENSCJAP00000069747 ENSCJAP00000070024 ENSCJAP00000070024 ENSCJAP00000070784 ENSCJAP00000070784 ENSCJAP00000070799 ENSCJAP00000070799 HBZ HBZ TDO2 TDO2 PXDN PXDN CYP7B1 CYP7B1 LOC100409504 LOC100409504 CYP39A1 CYP39A1 LOC100392617 LOC100392617 CYP4F12 CYP4F12 AMBP AMBP HBQ1 HBQ1 SRC SRC ENSCJAP00000074054 ENSCJAP00000074054 ENSCJAP00000074127 ENSCJAP00000074127 ENSCJAP00000074376 ENSCJAP00000074376 PTGES2 PTGES2 CAT CAT B3GNTL1 B3GNTL1 CYBA CYBA CYP7A1 CYP7A1 ENSCJAP00000075886 ENSCJAP00000075886 HBE1 HBE1 CYP2A13 CYP2A13 CYP2C8-2 CYP2C8-2 ENSCJAP00000076790 ENSCJAP00000076790 LOC100403393 LOC100403393 LOC100410611 LOC100410611 CYP4F22 CYP4F22 DUOX2 DUOX2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
IDO1Indoleamine 2,3-dioxygenase 1. (402 aa)
MBMyoglobin; Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles; Belongs to the globin family. (192 aa)
HMOX1Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. (288 aa)
CYP24A1Cytochrome P450 family 24 subfamily A member 1; Belongs to the cytochrome P450 family. (514 aa)
HCCSCytochrome c heme lyase; Links covalently the heme group to the apoprotein of cytochrome c. (268 aa)
CYP19A1Aromatase; Catalyzes the formation of aromatic C18 estrogens from C19 androgens. (503 aa)
CYP8B1Cytochrome P450 family 8 subfamily B member 1; Belongs to the cytochrome P450 family. (495 aa)
GUCY1A1Guanylate cyclase soluble subunit alpha-3 isoform A; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (690 aa)
CYP21A2Cytochrome P450 family 21 subfamily A member 2; Belongs to the cytochrome P450 family. (490 aa)
DUOX1Dual oxidase 1. (1551 aa)
LOC100415600Uncharacterized protein; Belongs to the cytochrome P450 family. (527 aa)
CYP2D19Cytochrome P450 2D19; Responsible for the metabolism of many drugs and environmental chemicals that it oxidizes. (497 aa)
C1orf194Chromosome 1 open reading frame 194. (169 aa)
CCNDBP1Cyclin-D1-binding protein 1. (360 aa)
CYB561D1Cytochrome b561 family member D1. (251 aa)
RTTNRotatin. (2228 aa)
CYP26B1Cytochrome P450 family 26 subfamily B member 1; Belongs to the cytochrome P450 family. (512 aa)
SDHCUncharacterized protein. (210 aa)
CYP2E1Uncharacterized protein; Belongs to the cytochrome P450 family. (528 aa)
CYB561D2Cytochrome b561 domain-containing protein 2. (222 aa)
CYBBCytochrome b-245 beta chain. (570 aa)
PTGS2Prostaglandin-endoperoxide synthase 2. (604 aa)
SUOXSulfite oxidase. (545 aa)
IDO2Indoleamine 2,3-dioxygenase 2. (408 aa)
CYP27B1Cytochrome P450 family 27 subfamily B member 1; Belongs to the cytochrome P450 family. (509 aa)
CYP46A1Cytochrome P450 family 46 subfamily A member 1; Belongs to the cytochrome P450 family. (500 aa)
TTI2TELO2-interacting protein 2. (508 aa)
CYP26C1Cytochrome P450 family 26 subfamily C member 1; Belongs to the cytochrome P450 family. (522 aa)
CYP26A1Cytochrome P450 family 26 subfamily A member 1; Belongs to the cytochrome P450 family. (497 aa)
NOS1Nitric oxide synthase 1. (1468 aa)
CYP2R1Cytochrome P450 family 2 subfamily R member 1; Belongs to the cytochrome P450 family. (501 aa)
GUCY1A2Guanylate cyclase 1 soluble subunit alpha 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (758 aa)
CYP27C1Cytochrome P450 family 27 subfamily C member 1; Belongs to the cytochrome P450 family. (416 aa)
DGCR8Microprocessor complex subunit DGCR8 isoform 1. (773 aa)
SDHDSuccinate dehydrogenase [ubiquinone] cytochrome b small subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family. (159 aa)
CYP27A1Cytochrome P450 family 27 subfamily A member 1; Belongs to the cytochrome P450 family. (531 aa)
TPOThyroid peroxidase. (769 aa)
HBMHemoglobin mu chain (Predicted); Belongs to the globin family. (141 aa)
F6RYT9_CALJAGLOBIN domain-containing protein; Belongs to the globin family. (135 aa)
CYB5D2Cytochrome b5 domain containing 2; Belongs to the cytochrome b5 family. (264 aa)
NOS2Nitric oxide synthase; Produces nitric oxide (NO). (1154 aa)
TBXAS1Uncharacterized protein; Belongs to the cytochrome P450 family. (580 aa)
CYGBCytoglobin; Belongs to the globin family. (190 aa)
CYP51A1Uncharacterized protein; Belongs to the cytochrome P450 family. (509 aa)
FA2HFatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...] (372 aa)
HRGHistidine rich glycoprotein. (524 aa)
PXDNLPeroxidasin like. (1457 aa)
CYP2F1Cytochrome P450 family 2 subfamily F member 1; Belongs to the cytochrome P450 family. (491 aa)
SLC48A1Solute carrier family 48 member 1. (146 aa)
FLVCR1Feline leukemia virus subgroup C receptor-related protein 1. (555 aa)
CYP3A5Uncharacterized protein. (503 aa)
CYP2W1Cytochrome P450 family 2 subfamily W member 1; Belongs to the cytochrome P450 family. (490 aa)
CYP2C76Cytochrome P450 2C76; Belongs to the cytochrome P450 family. (489 aa)
NR1D1Nuclear receptor subfamily 1 group D member 1. (614 aa)
CYP2J2Cytochrome P450 family 2 subfamily J member 2; Belongs to the cytochrome P450 family. (477 aa)
F7I7J6_CALJAUncharacterized protein. (263 aa)
LOC100410987Cytochrome c oxidase assembly protein COX15 homolog isoform 1. (410 aa)
EPXEosinophil peroxidase. (715 aa)
LPOLactoperoxidase. (714 aa)
MPOMyeloperoxidase. (744 aa)
CYP1A1Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. (512 aa)
CYP1A2Cytochrome P450 1A2; A cytochrome P450 monooxygenase involved in the metabolism of various endogenous substrates, including fatty acids, steroid hormones and vitamins. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Exhibits high catalytic activity for the formation of hydroxyestrogens from estrone (E1) and 17beta-estradiol (E2), namely 2-hydroxy E1 and E [...] (516 aa)
CYP17A1Uncharacterized protein; Belongs to the cytochrome P450 family. (508 aa)
RSAD1Radical S-adenosyl methionine domain-containing protein; May be a heme chaperone, appears to bind heme. Homologous bacterial proteins do not have oxygen-independent coproporphyrinogen- III oxidase activity. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L- methionine; Belongs to the anaerobic coproporphyrinogen-III oxidase family. (442 aa)
ADGBAndroglobin; Belongs to the peptidase C2 family. (1526 aa)
CYP2U1Cytochrome P450 family 2 subfamily U member 1; Belongs to the cytochrome P450 family. (544 aa)
F7B0K7_CALJAUncharacterized protein; Belongs to the cytochrome P450 family. (510 aa)
CYP2B6Cytochrome P450 family 2 subfamily B member 6; Belongs to the cytochrome P450 family. (491 aa)
CYP2S1Cytochrome P450 family 2 subfamily S member 1; Belongs to the cytochrome P450 family. (503 aa)
ENSCJAP00000037571Hemoglobin subunit gamma. (125 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1203 aa)
CYP4V2Cytochrome P450 family 4 subfamily V member 2; Belongs to the cytochrome P450 family. (525 aa)
KLKB1Kallikrein B1; Belongs to the peptidase S1 family. (638 aa)
FLVCR2Feline leukemia virus subgroup C receptor-related protein 2 isoform 1. (520 aa)
CYP4A11Uncharacterized protein. (486 aa)
CYP4Z1Cytochrome P450 family 4 subfamily Z member 1; Belongs to the cytochrome P450 family. (505 aa)
CYC1Cytochrome c1, heme protein, mitochondrial. (325 aa)
CYP11B1Uncharacterized protein; Belongs to the cytochrome P450 family. (584 aa)
HEBP1Heme-binding protein 1. (189 aa)
PTGS1Prostaglandin-endoperoxide synthase 1. (632 aa)
F6TTF3_CALJAUncharacterized protein. (135 aa)
JAK2Tyrosine-protein kinase. (1132 aa)
CYP2C8Cytochrome P450 family 2 subfamily C member 8. (461 aa)
CYP3A21Cytochrome P450 3A21; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. (527 aa)
ABCB6ATP binding cassette subfamily B member 6 (Langereis blood group). (843 aa)
BTBD6BTB domain containing 6. (538 aa)
THAP4THAP-type domain-containing protein. (610 aa)
GUCY1B1Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (651 aa)
HBQ1_1Theta 1 globin (Predicted); Belongs to the globin family. (142 aa)
BACH1BTB domain and CNC homolog 1. (736 aa)
STEAP4STEAP4 metalloreductase. (459 aa)
ENSCJAP00000054842Uncharacterized protein. (172 aa)
CYP1B1Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (548 aa)
ENSCJAP00000055709Uncharacterized protein. (302 aa)
LOC100413276Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
HEBP2Heme-binding protein 2. (205 aa)
B3GNT8Hexosyltransferase. (397 aa)
NGBNeuroglobin; Belongs to the globin family. (151 aa)
CYB5R4Cytochrome b5 reductase 4. (554 aa)
LOC100406761Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
PTGISProstacyclin synthase; Catalyzes the isomerization of prostaglandin H2 to prostacyclin (= prostaglandin I2); Belongs to the cytochrome P450 family. (501 aa)
PGRMC1Progesterone receptor membrane component 1; Belongs to the cytochrome b5 family. (237 aa)
CYP4X1Cytochrome P450 family 4 subfamily X member 1; Belongs to the cytochrome P450 family. (509 aa)
LOC100401718Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
ENSCJAP00000061810Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
LOC108593648Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa)
CYP20A1Cytochrome P450 family 20 subfamily A member 1. (470 aa)
CCDC160Coiled-coil domain containing 160. (322 aa)
PGRMC2Progesterone receptor membrane component 2; Belongs to the cytochrome b5 family. (248 aa)
ENSCJAP00000068039Cytochrome P450 3A21. (540 aa)
CYP11A1Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...] (552 aa)
CYP4F2Cytochrome P450 family 4 subfamily F member 2; Belongs to the cytochrome P450 family. (551 aa)
ENSCJAP00000069747Uncharacterized protein. (153 aa)
ENSCJAP00000070024Uncharacterized protein. (194 aa)
ENSCJAP00000070784Uncharacterized protein; Belongs to the cytochrome P450 family. (476 aa)
ENSCJAP00000070799Uncharacterized protein. (480 aa)
HBZHemoglobin subunit zeta; Belongs to the globin family. (192 aa)
TDO2Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. (440 aa)
PXDNUncharacterized protein. (691 aa)
CYP7B1Cytochrome P450 family 7 subfamily B member 1; Belongs to the cytochrome P450 family. (548 aa)
LOC100409504DUF1794 domain-containing protein. (163 aa)
CYP39A1Cytochrome P450 family 39 subfamily A member 1; Belongs to the cytochrome P450 family. (474 aa)
LOC100392617Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family. (279 aa)
CYP4F12Cytochrome P450 family 4 subfamily F member 12; Belongs to the cytochrome P450 family. (526 aa)
AMBPAlpha-1-microglobulin/bikunin precursor. (372 aa)
HBQ1GLOBIN domain-containing protein; Belongs to the globin family. (374 aa)
SRCTyrosine-protein kinase. (553 aa)
ENSCJAP00000074054Uncharacterized protein. (131 aa)
ENSCJAP00000074127Succinate dehydrogenase [ubiquinone] cytochrome b small subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family. (80 aa)
ENSCJAP00000074376Uncharacterized protein. (138 aa)
PTGES2Glutaredoxin domain-containing protein. (552 aa)
CATCatalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Promotes growth of cells (By similarity); Belongs to the catalase family. (556 aa)
B3GNTL1UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase like 1. (389 aa)
CYBAUncharacterized protein. (223 aa)
CYP7A1Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. (504 aa)
ENSCJAP00000075886Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (767 aa)
HBE1Hemoglobin subunit gamma; Gamma chains make up the fetal hemoglobin F, in combination with alpha chains. (147 aa)
CYP2A13Cytochrome P450 family 2 subfamily A member 13; Belongs to the cytochrome P450 family. (494 aa)
CYP2C8-2Uncharacterized protein; Belongs to the cytochrome P450 family. (504 aa)
ENSCJAP00000076790Uncharacterized protein; Belongs to the cytochrome P450 family. (597 aa)
LOC100403393Cytochrome b5 type B; Belongs to the cytochrome b5 family. (150 aa)
LOC100410611Hemoglobin subunit beta; Involved in oxygen transport from the lung to the various peripheral tissues. (147 aa)
CYP4F22Cytochrome P450 family 4 subfamily F member 22; Belongs to the cytochrome P450 family. (601 aa)
DUOX2Dual oxidase 2. (1546 aa)
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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