STRINGSTRING
NOG NOG BMP5 BMP5 BMP7 BMP7 BMP4 BMP4 FGFR2 FGFR2 SOSTDC1 SOSTDC1 HOXD13 HOXD13 FGF10 FGF10 TP63 TP63 HIF1A HIF1A CECR2 CECR2 NODAL NODAL RDH10 RDH10 GDF7 GDF7 LUZP1 LUZP1 OVOL2 OVOL2 AR AR
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
BMP5Bone morphogenetic protein 5. (472 aa)
BMP7Bone morphogenetic protein 7. (430 aa)
BMP4Bone morphogenetic protein 4 preproprotein. (408 aa)
FGFR2Fibroblast growth factor receptor. (822 aa)
SOSTDC1CTCK domain-containing protein. (230 aa)
HOXD13Homeobox protein Hox-D13. (344 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (210 aa)
TP63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (850 aa)
CECR2CECR2 histone acetyl-lysine reader. (1484 aa)
NODALNodal growth differentiation factor. (346 aa)
RDH10Retinol dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (341 aa)
GDF7Growth differentiation factor 7. (449 aa)
LUZP1Leucine zipper protein 1. (1074 aa)
OVOL2Transcription factor Ovo-like 2. (275 aa)
ARAndrogen receptor. (887 aa)
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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