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| | CTNNBIP1 | Catenin beta interacting protein 1. (81 aa) |
| | LATS1 | Large tumor suppressor kinase 1. (1129 aa) |
| | FRZB | Frizzled related protein. (325 aa) |
| | ENSCCAP00000000807 | Uncharacterized protein. (144 aa) |
| | ENSCCAP00000000866 | Uncharacterized protein. (141 aa) |
| | WNT11 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa) |
| | LOC108299097 | Uncharacterized protein. (139 aa) |
| | DACT3 | Dishevelled binding antagonist of beta catenin 3. (631 aa) |
| | SCYL2 | SCY1 like pseudokinase 2. (933 aa) |
| | RBMS3 | RNA binding motif single stranded interacting protein 3. (437 aa) |
| | PTPRO | Protein tyrosine phosphatase receptor type O. (1216 aa) |
| | SOX9 | SRY-box transcription factor 9. (509 aa) |
| | ENSCCAP00000001846 | Uncharacterized protein. (113 aa) |
| | ENSCCAP00000002126 | Uncharacterized protein. (125 aa) |
| | FERMT1 | Fermitin family member 1. (378 aa) |
| | NPPA | Natriuretic peptide A. (153 aa) |
| | SOSTDC1 | Sclerostin domain containing 1. (230 aa) |
| | STK11 | Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (433 aa) |
| | SHISA6 | Shisa family member 6. (554 aa) |
| | BMP2 | Bone morphogenetic protein 2. (396 aa) |
| | ENSCCAP00000003031 | Uncharacterized protein. (146 aa) |
| | APOE | Apolipoprotein E. (320 aa) |
| | ENSCCAP00000003399 | Uncharacterized protein. (113 aa) |
| | FZD4 | Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (543 aa) |
| | DRAXIN | Draxin; Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway. (350 aa) |
| | AXIN1 | Axin 1. (867 aa) |
| | LATS2 | Non-specific serine/threonine protein kinase. (1085 aa) |
| | ISL1 | ISL LIM homeobox 1. (349 aa) |
| | NOG | Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa) |
| | CHD8 | Chromodomain-helicase-DNA-binding protein 8; DNA helicase that acts as a chromatin remodeling factor and regulates transcription. Acts as a transcription repressor by remodeling chromatin structure and recruiting histone H1 to target genes. Suppresses p53/TP53-mediated apoptosis by recruiting histone H1 and preventing p53/TP53 transactivation activity. Acts as a negative regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) activity. Negatively regulates CTNNB1-targeted gene expression by being recruited specifically to the promoter regions of several CTNNB1 responsive [...] (2589 aa) |
| | ENSCCAP00000005634 | Hist_deacetyl domain-containing protein. (305 aa) |
| | MLLT3 | MLLT3 super elongation complex subunit. (569 aa) |
| | INVS | Inversin. (1080 aa) |
| | LOC108292702 | CTNNB1_binding domain-containing protein. (169 aa) |
| | TLE3 | TLE family member 3, transcriptional corepressor. (786 aa) |
| | NPHP4 | Nephrocystin 4. (1426 aa) |
| | ENSCCAP00000010332 | Uncharacterized protein. (139 aa) |
| | DKK3 | Dickkopf WNT signaling pathway inhibitor 3. (350 aa) |
| | AXIN2 | Axin 2. (842 aa) |
| | CBY1 | Chibby family member 1, beta catenin antagonist. (138 aa) |
| | SOST | Sclerostin. (213 aa) |
| | SNAI2 | Snail family transcriptional repressor 2. (268 aa) |
| | CCDC88C | Calponin-homology (CH) domain-containing protein. (2025 aa) |
| | PRKN | E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (465 aa) |
| | NKD2 | NKD inhibitor of WNT signaling pathway 2. (450 aa) |
| | NOTUM | Notum, palmitoleoyl-protein carboxylesterase. (503 aa) |
| | GSK3B | Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (434 aa) |
| | RUVBL2 | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (468 aa) |
| | MESP1 | Mesoderm posterior bHLH transcription factor 1. (257 aa) |
| | STK3 | Serine/threonine kinase 3. (523 aa) |
| | EMD | Emerin. (259 aa) |
| | CTNNB1 | Catenin beta 1. (781 aa) |
| | DACT1 | Dishevelled binding antagonist of beta catenin 1. (837 aa) |
| | DAB2IP | DAB2 interacting protein. (1193 aa) |
| | GLI1 | GLI family zinc finger 1. (1106 aa) |
| | WNT5A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa) |
| | CTHRC1 | Collagen triple helix repeat containing 1. (243 aa) |
| | TBX18 | T-box transcription factor 18. (607 aa) |
| | STK4 | Serine/threonine kinase 4. (487 aa) |
| | ENSCCAP00000017839 | Uncharacterized protein. (136 aa) |
| | LIMD1 | LIM domains containing 1. (676 aa) |
| | TMEM170B | Transmembrane protein 170B. (132 aa) |
| | DAB2 | DAB adaptor protein 2. (767 aa) |
| | SFRP2 | Secreted frizzled related protein 2. (296 aa) |
| | BICC1 | BicC family RNA binding protein 1. (974 aa) |
| | LZTS2 | Leucine zipper putative tumor suppressor 2; Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. May negatively regulate axonal outgrowth by preventing the formation of microtubule bundles that are necessary for transport within the elongating axon. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta- catenin. (669 aa) |
| | AMFR | Autocrine motility factor receptor. (643 aa) |
| | G3BP1 | G3BP stress granule assembly factor 1. (466 aa) |
| | SHISA3 | Shisa family member 3. (237 aa) |
| | IGFBP4 | Insulin like growth factor binding protein 4. (258 aa) |
| | ENSCCAP00000023536 | PTN_MK_N domain-containing protein. (92 aa) |
| | GLI3 | GLI family zinc finger 3. (1577 aa) |
| | TLE7 | TLE family member 7. (441 aa) |
| | NKX2-5 | NK2 homeobox 5. (324 aa) |
| | SFRP1 | Secreted frizzled related protein 1. (314 aa) |
| | SDHAF2 | Succinate dehydrogenase assembly factor 2, mitochondrial; Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SDHA of the SDH catalytic dimer. (166 aa) |
| | AMER1 | APC membrane recruitment protein 1. (804 aa) |
| | MDK | Uncharacterized protein. (144 aa) |
| | UBAC2 | UBA domain containing 2. (392 aa) |
| | CYLD | CYLD lysine 63 deubiquitinase; Belongs to the peptidase C19 family. (956 aa) |
| | SOX13 | SRY-box transcription factor 13. (615 aa) |
| | LOC108308794 | Uncharacterized protein. (786 aa) |
| | TLE1 | TLE family member 1, transcriptional corepressor. (779 aa) |
| | TMEM131L | Transmembrane 131 like. (1614 aa) |
| | AMER2 | APC membrane recruitment protein 2. (550 aa) |
| | FRMD8 | FERM domain containing 8. (464 aa) |
| | DDIT3 | DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (169 aa) |
| | MAPK14 | Mitogen-activated protein kinase. (360 aa) |
| | TLE2 | TLE family member 2, transcriptional corepressor. (691 aa) |
| | TCF7L2 | Transcription factor 7 like 2. (430 aa) |
| | PRICKLE1 | Prickle planar cell polarity protein 1. (829 aa) |
| | SIAH2 | E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (324 aa) |
| | APC | APC regulator of WNT signaling pathway. (2860 aa) |
| | APC2 | APC regulator of WNT signaling pathway 2. (2172 aa) |
| | SFRP4 | Secreted frizzled related protein 4. (368 aa) |
| | ANKRD6 | Ankyrin repeat domain 6. (717 aa) |
| | WWTR1 | WW domain containing transcription regulator 1. (400 aa) |
| | OTUD5 | OTU deubiquitinase 5. (567 aa) |
| | ENSCCAP00000030778 | Uncharacterized protein. (94 aa) |
| | ENSCCAP00000031495 | Uncharacterized protein. (141 aa) |
| | TLE4 | TLE family member 4, transcriptional corepressor. (792 aa) |
| | NKD1 | NKD inhibitor of WNT signaling pathway 1. (470 aa) |
| | SFRP5 | Secreted frizzled related protein 5. (315 aa) |
| | SOX17 | SRY-box transcription factor 17. (408 aa) |
| | DKK2 | Dickkopf WNT signaling pathway inhibitor 2. (259 aa) |
| | ZNRF3 | Zinc and ring finger 3. (933 aa) |
| | SHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (464 aa) |
| | LMBR1L | Limb development membrane protein 1 like; Belongs to the LIMR family. (548 aa) |
| | NOTCH1 | Notch receptor 1. (2550 aa) |
| | SOX10 | SRY-box transcription factor 10. (468 aa) |
| | LRP4 | LDL receptor related protein 4. (1905 aa) |
| | TLE6 | TLE family member 6, subcortical maternal complex member. (569 aa) |
| | CTNND1 | Catenin delta 1. (967 aa) |
| | TNN | Tenascin N. (1191 aa) |
| | IGFBP1 | Uncharacterized protein. (234 aa) |
| | FUZ | Fuzzy planar cell polarity protein. (418 aa) |
| | MCC | MCC regulator of WNT signaling pathway. (1014 aa) |
| | CSNK1A1 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (365 aa) |
| | JADE1 | Jade family PHD finger 1. (779 aa) |
| | HECW1 | HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1. (1605 aa) |
| | MAD2L2 | Mitotic arrest deficient 2 like 2. (242 aa) |
| | DKK4 | Dickkopf WNT signaling pathway inhibitor 4. (224 aa) |
| | ENSCCAP00000038181 | Protein kinase domain-containing protein. (293 aa) |
| | FOXO1 | Forkhead box O1. (654 aa) |
| | TLE5 | TLE family member 5, transcriptional modulator. (248 aa) |
| | RBX1 | Ring-box 1. (108 aa) |
| | KREMEN1 | Kremen protein; Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6. (471 aa) |
| | PFDN5 | Uncharacterized protein. (154 aa) |
| | EGR1 | Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (543 aa) |
| | FZD6 | Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (706 aa) |
| | HDAC1 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa) |
| | TMEM64 | Transmembrane protein 64. (379 aa) |
| | DKK1 | Dickkopf WNT signaling pathway inhibitor 1. (266 aa) |
| | GSK3A | Glycogen synthase kinase 3 alpha; Belongs to the protein kinase superfamily. (483 aa) |
