36 items (Cercocebus atys) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSCATP00000000012	Protein kinase domain-containing protein. (231 aa)
	ENSCATP00000001061	UBIQUITIN_CONJUGAT_2 domain-containing protein. (147 aa)
	LOC105581053	UBIQUITIN_CONJUGAT_2 domain-containing protein. (147 aa)
	MAPK8	Mitogen-activated protein kinase. (384 aa)
	MAP2K7	Mitogen-activated protein kinase kinase 7. (517 aa)
	UBE2NL	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (89 aa)
	LOC105576738	Ubiquitin-like domain-containing protein. (134 aa)
	LOC105579396	Ubiquitin-like domain-containing protein. (156 aa)
	LOC105595668	Ubiquitin-like domain-containing protein. (126 aa)
	ENSCATP00000011808	Ubiquitin-like domain-containing protein. (130 aa)
	TRAF6	TNF receptor-associated factor 6; E3 ubiquitin ligase that, together with UBE2N and UBE2V1, mediates the synthesis of 'Lys-63'-linked-polyubiquitin chains conjugated to proteins, such as IKBKG, IRAK1, AKT1 and AKT2. Also mediates ubiquitination of free/unanchored polyubiquitin chain that leads to MAP3K7 activation. Mediates activation of NF-kappa-B and JUN. May be essential for the formation of functional osteoclasts. Seems to also play a role in dendritic cells (DCs) maturation and/or activation. Represses c-Myb-mediated transactivation, in B-lymphocytes. Adapter protein that seems to [...] (522 aa)
	IKBKG	Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (419 aa)
	LOC105583935	UBIQUITIN_CONJUGAT_2 domain-containing protein. (87 aa)
	ENSCATP00000013712	UBIQUITIN_CONJUGAT_2 domain-containing protein. (140 aa)
	TAB2	TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (693 aa)
	UBA52	Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
	NOD2	Nucleotide binding oligomerization domain containing 2. (1044 aa)
	MAPK9	Mitogen-activated protein kinase. (424 aa)
	IRAK2	Interleukin 1 receptor associated kinase 2. (625 aa)
	TAB1	TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (504 aa)
	NOD1	Nucleotide binding oligomerization domain containing 1. (953 aa)
	ENSCATP00000031033	Ubiquitin-like domain-containing protein. (149 aa)
	MAP3K20	Mitogen-activated protein kinase kinase kinase 20. (788 aa)
	ENSCATP00000034768	Ubiquitin-like domain-containing protein. (144 aa)
	ENSCATP00000035134	Ubiquitin-like domain-containing protein. (146 aa)
	MAP2K4	Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (416 aa)
	LOC105597804	UBIQUITIN_CONJUGAT_2 domain-containing protein. (132 aa)
	RIPK2	Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (540 aa)
	LOC105598099	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
	RPS27A	Ubiquitin-like domain-containing protein. (156 aa)
	MAPK10	Mitogen-activated protein kinase. (474 aa)
	TAB3	TGF-beta activated kinase 1 (MAP3K7) binding protein 3. (712 aa)
	MAP3K7	Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (586 aa)
	IRAK1	Interleukin 1 receptor associated kinase 1. (721 aa)
	ENSCATP00000043644	Ubiquitin-like domain-containing protein. (120 aa)
	UBE2N	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)

Your Current Organism:

Cercocebus atys

NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSCATP00000000012	IRAK1	ENSCATP00000000012	ENSCATP00000043465	Protein kinase domain-containing protein.	Interleukin 1 receptor associated kinase 1.	0.466
ENSCATP00000000012	IRAK2	ENSCATP00000000012	ENSCATP00000022512	Protein kinase domain-containing protein.	Interleukin 1 receptor associated kinase 2.	0.484
ENSCATP00000000012	MAP2K7	ENSCATP00000000012	ENSCATP00000002831	Protein kinase domain-containing protein.	Mitogen-activated protein kinase kinase 7.	0.909
ENSCATP00000000012	MAP3K20	ENSCATP00000000012	ENSCATP00000031771	Protein kinase domain-containing protein.	Mitogen-activated protein kinase kinase kinase 20.	0.839
ENSCATP00000000012	MAP3K7	ENSCATP00000000012	ENSCATP00000042911	Protein kinase domain-containing protein.	Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.	0.974
ENSCATP00000000012	MAPK10	ENSCATP00000000012	ENSCATP00000042261	Protein kinase domain-containing protein.	Mitogen-activated protein kinase.	0.976
ENSCATP00000000012	MAPK8	ENSCATP00000000012	ENSCATP00000002330	Protein kinase domain-containing protein.	Mitogen-activated protein kinase.	0.974
ENSCATP00000000012	MAPK9	ENSCATP00000000012	ENSCATP00000019872	Protein kinase domain-containing protein.	Mitogen-activated protein kinase.	0.972
ENSCATP00000000012	RIPK2	ENSCATP00000000012	ENSCATP00000040630	Protein kinase domain-containing protein.	Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains.	0.532
ENSCATP00000000012	TAB1	ENSCATP00000000012	ENSCATP00000023562	Protein kinase domain-containing protein.	TGF-beta activated kinase 1 (MAP3K7) binding protein 1.	0.860
ENSCATP00000000012	TAB2	ENSCATP00000000012	ENSCATP00000016445	Protein kinase domain-containing protein.	TGF-beta activated kinase 1 (MAP3K7) binding protein 2.	0.860
ENSCATP00000000012	TAB3	ENSCATP00000000012	ENSCATP00000042720	Protein kinase domain-containing protein.	TGF-beta activated kinase 1 (MAP3K7) binding protein 3.	0.863
ENSCATP00000000012	TRAF6	ENSCATP00000000012	ENSCATP00000012971	Protein kinase domain-containing protein.	TNF receptor-associated factor 6; E3 ubiquitin ligase that, together with UBE2N and UBE2V1, mediates the synthesis of 'Lys-63'-linked-polyubiquitin chains conjugated to proteins, such as IKBKG, IRAK1, AKT1 and AKT2. Also mediates ubiquitination of free/unanchored polyubiquitin chain that leads to MAP3K7 activation. Mediates activation of NF-kappa-B and JUN. May be essential for the formation of functional osteoclasts. Seems to also play a role in dendritic cells (DCs) maturation and/or activation. Represses c-Myb-mediated transactivation, in B-lymphocytes. Adapter protein that seems to [...]	0.603
ENSCATP00000001061	ENSCATP00000011808	ENSCATP00000001061	ENSCATP00000011808	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Ubiquitin-like domain-containing protein.	0.978
ENSCATP00000001061	ENSCATP00000013712	ENSCATP00000001061	ENSCATP00000013712	UBIQUITIN_CONJUGAT_2 domain-containing protein.	UBIQUITIN_CONJUGAT_2 domain-containing protein.	0.942
ENSCATP00000001061	ENSCATP00000031033	ENSCATP00000001061	ENSCATP00000031033	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Ubiquitin-like domain-containing protein.	0.978
ENSCATP00000001061	ENSCATP00000034768	ENSCATP00000001061	ENSCATP00000034768	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Ubiquitin-like domain-containing protein.	0.978
ENSCATP00000001061	ENSCATP00000035134	ENSCATP00000001061	ENSCATP00000035134	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Ubiquitin-like domain-containing protein.	0.978
ENSCATP00000001061	ENSCATP00000043644	ENSCATP00000001061	ENSCATP00000043644	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Ubiquitin-like domain-containing protein.	0.995
ENSCATP00000001061	IKBKG	ENSCATP00000001061	ENSCATP00000013169	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.	0.684