STRINGSTRING
GDF7 GDF7 BMP15 BMP15 GDF6 GDF6 GDF11 GDF11 LOC102144954 LOC102144954 GDF3 GDF3 ACVRL1 ACVRL1 NODAL NODAL BMP10 BMP10 SDCBP SDCBP INHBA INHBA ENG ENG TWSG1 TWSG1 ENSMFAP00000035525 ENSMFAP00000035525 TGFBR2 TGFBR2 ACVR2A ACVR2A SMAD4 SMAD4 GDF5 GDF5 RBPMS RBPMS GDF10 GDF10 ACVR1 ACVR1 ENSMFAP00000029266 ENSMFAP00000029266 TGFBR1 TGFBR1 ENSMFAP00000025331 ENSMFAP00000025331 BMP2 BMP2 INHBB INHBB INHBE INHBE BMP3 BMP3 INHBC INHBC BMP7 BMP7 BMPR2 BMPR2 GDF2 GDF2 ENSMFAP00000017173 ENSMFAP00000017173 BMP5 BMP5 TGFB3 TGFB3 HFE HFE BMP4 BMP4 DAB2 DAB2 BMP6 BMP6 BMPR1A BMPR1A INHA INHA TGFB2 TGFB2 LEFTY1 LEFTY1 TGFB1 TGFB1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GDF7Growth differentiation factor 7. (450 aa)
BMP15Bone morphogenetic protein 15. (393 aa)
GDF6Growth differentiation factor 6. (455 aa)
GDF11Growth differentiation factor 11. (342 aa)
LOC102144954Left-right determination factor. (366 aa)
GDF3Growth differentiation factor 3. (364 aa)
ACVRL1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa)
NODALNodal growth differentiation factor. (347 aa)
BMP10Bone morphogenetic protein 10. (424 aa)
SDCBPUncharacterized protein. (324 aa)
INHBAInhibin subunit beta A. (426 aa)
ENGEndoglin. (555 aa)
TWSG1Twisted gastrulation BMP signaling modulator 1. (223 aa)
ENSMFAP00000035525TGF_BETA_2 domain-containing protein. (347 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
ACVR2ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (513 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
GDF5Growth differentiation factor 5. (499 aa)
RBPMSRNA binding protein, mRNA processing factor. (219 aa)
GDF10Bone morphogenetic protein 3; Belongs to the TGF-beta family. (477 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
ENSMFAP00000029266TGF_BETA_2 domain-containing protein. (344 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (504 aa)
ENSMFAP00000025331Uncharacterized protein. (259 aa)
BMP2Bone morphogenetic protein 2. (544 aa)
INHBBInhibin subunit beta B. (360 aa)
INHBEInhibin subunit beta E. (351 aa)
BMP3Bone morphogenetic protein 3; Belongs to the TGF-beta family. (474 aa)
INHBCInhibin subunit beta C. (352 aa)
BMP7Bone morphogenetic protein 7. (431 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
GDF2Growth differentiation factor 2. (429 aa)
ENSMFAP00000017173PDZ domain-containing protein. (255 aa)
BMP5Bone morphogenetic protein 5. (454 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
HFEHomeostatic iron regulator; Belongs to the MHC class I family. (348 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
DAB2DAB adaptor protein 2. (770 aa)
BMP6Bone morphogenetic protein 6. (509 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
INHAInhibin alpha chain; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition; Belongs to the TGF-beta family. (366 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
LEFTY1Left-right determination factor. (366 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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