STRINGSTRING
ADRB2 ADRB2 BMPR1B BMPR1B ACVR1 ACVR1 FBN2 FBN2 ATP2B1 ATP2B1 PTN PTN MEF2C MEF2C RXRA RXRA BMP2 BMP2 ACTN3 ACTN3 WNT10B WNT10B FAM20C FAM20C NELL1 NELL1 KL KL ADGRV1 ADGRV1 P2RX7 P2RX7 BMP7 BMP7 BMPR2 BMPR2 OSR2 OSR2 TGFB3 TGFB3 ALOX5 ALOX5 ANO6 ANO6 ATRAID ATRAID FZD9 FZD9 BMP4 BMP4 BMP6 BMP6 CCN1 CCN1 BMPR1A BMPR1A SMAD3 SMAD3 TENT5A TENT5A TGFB1 TGFB1 ACVR2A ACVR2A PKDCC PKDCC RXRB RXRB GPM6B GPM6B LTF LTF SLC8A1 SLC8A1 WNT4 WNT4 ACVR2B ACVR2B ISG15 ISG15 TFAP2A TFAP2A OSR1 OSR1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ADRB2Adrenergic receptor beta 2. (415 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
FBN2Fibrillin 2. (2912 aa)
ATP2B1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1249 aa)
PTNPleiotrophin. (172 aa)
MEF2CMyocyte enhancer factor 2C. (483 aa)
RXRARetinoid X receptor alpha. (443 aa)
BMP2Bone morphogenetic protein 2. (544 aa)
ACTN3Actinin alpha 3 (gene/pseudogene). (942 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
FAM20CFAM20C golgi associated secretory pathway kinase. (584 aa)
NELL1Neural EGFL like 1. (838 aa)
KLKlotho peptide; May have weak glycosidase activity towards glucuronylated steroids. However, it lacks essential active site Glu residues at positions 241 and 874, suggesting it may be inactive as a glycosidase in vivo. May be involved in the regulation of calcium and phosphorus homeostasis by inhibiting the synthesis of active vitamin D (By similarity). Essential factor for the specific interaction between FGF23 and FGFR1 (By similarity). (1014 aa)
ADGRV1Adhesion G protein-coupled receptor V1; Belongs to the G-protein coupled receptor 2 family. (6306 aa)
P2RX7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (595 aa)
BMP7Bone morphogenetic protein 7. (431 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
OSR2Odd-skipped related transciption factor 2. (402 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
ALOX5Arachidonate 5-lipoxygenase. (674 aa)
ANO6Anoctamin. (931 aa)
ATRAIDAll-trans retinoic acid induced differentiation factor. (284 aa)
FZD9Frizzled class receptor 9; Belongs to the G-protein coupled receptor Fz/Smo family. (591 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
BMP6Bone morphogenetic protein 6. (509 aa)
CCN1Cellular communication network factor 1. (381 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
TENT5ATerminal nucleotidyltransferase 5A. (461 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
ACVR2ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (513 aa)
PKDCCProtein kinase domain containing, cytoplasmic. (432 aa)
RXRBRetinoid X receptor beta. (537 aa)
GPM6BGlycoprotein M6B. (305 aa)
LTFLactotransferrin; Belongs to the transferrin family. (710 aa)
SLC8A1Solute carrier family 8 member A1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (973 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
ACVR2BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (518 aa)
ISG15ISG15 ubiquitin like modifier. (165 aa)
TFAP2ATranscription factor AP-2 alpha. (439 aa)
OSR1Odd-skipped related transcription factor 1. (266 aa)
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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