STRINGSTRING
F5 F5 TGFB1 TGFB1 PSMA5 PSMA5 S100A11 S100A11 NHLRC2 NHLRC2 GNS GNS CRACR2A CRACR2A GRN GRN ENSMFAP00000000867 ENSMFAP00000000867 PSMD3 PSMD3 HUWE1 HUWE1 TRAPPC1 TRAPPC1 ENSMFAP00000001720 ENSMFAP00000001720 OLFM4 OLFM4 ATG7 ATG7 NFKB1 NFKB1 CTSA CTSA CTSG CTSG PRDX4 PRDX4 GTPBP2 GTPBP2 CTSH CTSH CDA CDA PSMD6 PSMD6 PADI2 PADI2 SERPING1 SERPING1 SERPINB1 SERPINB1 ENSMFAP00000003583 ENSMFAP00000003583 ENSMFAP00000003951 ENSMFAP00000003951 ACLY ACLY MAPK1 MAPK1 FGG FGG PSMD14 PSMD14 CTSW CTSW TGFB2 TGFB2 GSDMD GSDMD FOLR2 FOLR2 PSMB7 PSMB7 SRGN SRGN GIP GIP TEX264 TEX264 SLPI SLPI EPX EPX HK3 HK3 IMPDH1 IMPDH1 CTSZ CTSZ F13A1 F13A1 VPS13A VPS13A FERMT3 FERMT3 ENSMFAP00000008901 ENSMFAP00000008901 DERA DERA PYGL PYGL CRISPLD2 CRISPLD2 ACTR10 ACTR10 ENSMFAP00000011440 ENSMFAP00000011440 TOR4A TOR4A GGH GGH ALOX5 ALOX5 SPACA7 SPACA7 ENSMFAP00000012490 ENSMFAP00000012490 TGFB3 TGFB3 ENSMFAP00000012889 ENSMFAP00000012889 ENSMFAP00000012946 ENSMFAP00000012946 LCN2 LCN2 ENSMFAP00000013449 ENSMFAP00000013449 ACTR1B ACTR1B VCP VCP ENSMFAP00000014245 ENSMFAP00000014245 KPNB1 KPNB1 MPO MPO ENSMFAP00000014556 ENSMFAP00000014556 HPSE HPSE ENSMFAP00000015967 ENSMFAP00000015967 PRSS57 PRSS57 TOLLIP TOLLIP PPBP PPBP TIMP2 TIMP2 LRRC7 LRRC7 PDGFB PDGFB PENK PENK ENSMFAP00000017173 ENSMFAP00000017173 SCG3 SCG3 SERPINI1 SERPINI1 PSMD13 PSMD13 PF4 PF4 PSMA2 PSMA2 DBNL DBNL ENSMFAP00000018989 ENSMFAP00000018989 GLA GLA HRG HRG MMP8 MMP8 ENSMFAP00000019661 ENSMFAP00000019661 VTI1B VTI1B PCSK1 PCSK1 THBS1 THBS1 S100A12 S100A12 OSCAR OSCAR PYCARD PYCARD PTPN6 PTPN6 DYNLT1 DYNLT1 ENSMFAP00000021023 ENSMFAP00000021023 ENSMFAP00000021666 ENSMFAP00000021666 BPI BPI DYNC1H1 DYNC1H1 ENSMFAP00000023104 ENSMFAP00000023104 FABP5 FABP5 GAS6 GAS6 GHRL GHRL AGL AGL CANT1 CANT1 OSTF1 OSTF1 FOLR3 FOLR3 ENSMFAP00000025331 ENSMFAP00000025331 SPTAN1 SPTAN1 ACAA1 ACAA1 SPP2 SPP2 AOC1 AOC1 VEGFB VEGFB IGF2 IGF2 C3 C3 IMPDH2 IMPDH2 VCL VCL S100A9 S100A9 FGB FGB FGA FGA ENSMFAP00000027831 ENSMFAP00000027831 CREG1 CREG1 C1orf35 C1orf35 ARG1 ARG1 CHIT1 CHIT1 LRG1 LRG1 CLU CLU ENSMFAP00000028786 ENSMFAP00000028786 ACTN2 ACTN2 GALNS GALNS S100P S100P DPP7 DPP7 FAM49B FAM49B PDXK PDXK PA2G4 PA2G4 GMFB GMFB VEGFD VEGFD CLEC3B CLEC3B GMFG GMFG TXNDC5 TXNDC5 ENSMFAP00000032355 ENSMFAP00000032355 IMPDH IMPDH VAT1 VAT1 RAB27A RAB27A AMPD3 AMPD3 COMMD9 COMMD9 XRCC6 XRCC6 AZU1 AZU1 EGF EGF VEGFC VEGFC DSN1 DSN1 GRP GRP PSMC3 PSMC3 HEXB HEXB ARSB ARSB PTX3 PTX3 JUP JUP DNAJC3 DNAJC3 HGF HGF HSPA6 HSPA6 FGR FGR CRISP3 CRISP3 SDCBP SDCBP QPCT QPCT LTF LTF ITIH4 ITIH4 STK11IP STK11IP PRTN3 PRTN3 SPARC SPARC CYFIP1 CYFIP1 TCN1 TCN1 RETN RETN SERPINF2 SERPINF2 DNASE1L1 DNASE1L1 ORM1 ORM1 CEP290 CEP290 PSMD7 PSMD7 ERP44 ERP44 ENSMFAP00000039848 ENSMFAP00000039848 NEU1 NEU1 GSN GSN BIN2 BIN2 FAF2 FAF2 HEBP2 HEBP2 KNG1 KNG1 COTL1 COTL1 ARSA ARSA DBH DBH GCG GCG ELANE ELANE PCYOX1L PCYOX1L PSMD11 PSMD11 F8 F8 GYG1 GYG1 ECM1 ECM1 NAPRT NAPRT A1BG A1BG ENSMFAP00000043886 ENSMFAP00000043886 XRCC5 XRCC5 PSMB1 PSMB1 APAF1 APAF1 PRG3 PRG3 VWF VWF S100A8 S100A8 ALAD ALAD ARHGAP9 ARHGAP9 CFD CFD SERPINE1 SERPINE1 PNP PNP PRKCD PRKCD CAB39 CAB39 DOCK2 DOCK2 FRK FRK
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
F5Coagulation factor V; Belongs to the multicopper oxidase family. (2181 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
S100A11Protein S100; Belongs to the S-100 family. (105 aa)
NHLRC2NHL repeat containing 2. (726 aa)
GNSGlucosamine (N-acetyl)-6-sulfatase. (584 aa)
CRACR2ACalcium release activated channel regulator 2A. (731 aa)
GRNUncharacterized protein. (593 aa)
ENSMFAP00000000867Uncharacterized protein. (376 aa)
PSMD3Proteasome 26S subunit, non-ATPase 3. (534 aa)
HUWE1HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1. (4390 aa)
TRAPPC1Trafficking protein particle complex subunit; Belongs to the TRAPP small subunits family. (145 aa)
ENSMFAP00000001720AAA domain-containing protein; Belongs to the AAA ATPase family. (384 aa)
OLFM4Olfactomedin 4. (512 aa)
ATG7Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] (704 aa)
NFKB1Nuclear factor kappa B subunit 1. (969 aa)
CTSACarboxypeptidase; Belongs to the peptidase S10 family. (494 aa)
CTSGCathepsin G; Belongs to the peptidase S1 family. (255 aa)
PRDX4Peroxiredoxin 4. (271 aa)
GTPBP2GTP binding protein 2. (602 aa)
CTSHCathepsin H; Belongs to the peptidase C1 family. (335 aa)
CDACytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (146 aa)
PSMD6Proteasome 26S subunit, non-ATPase 6. (442 aa)
PADI2Peptidyl arginine deiminase 2. (665 aa)
SERPING1Serpin family G member 1; Belongs to the serpin family. (500 aa)
SERPINB1Serpin family B member 1; Belongs to the serpin family. (379 aa)
ENSMFAP00000003583Uncharacterized protein. (379 aa)
ENSMFAP00000003951Ku domain-containing protein. (542 aa)
ACLYATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. (1155 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
FGGFibrinogen gamma chain. (453 aa)
PSMD1426S proteasome regulatory subunit N11. (310 aa)
CTSWCathepsin W; Belongs to the peptidase C1 family. (380 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
GSDMDGasdermin D. (518 aa)
FOLR2Folate receptor beta. (272 aa)
PSMB7Proteasome subunit beta. (302 aa)
SRGNSerglycin. (153 aa)
GIPGastric inhibitory polypeptide. (153 aa)
TEX264Testis expressed 264, ER-phagy receptor. (313 aa)
SLPISecretory leukocyte peptidase inhibitor. (132 aa)
EPXEosinophil peroxidase. (715 aa)
HK3Hexokinase 3. (923 aa)
IMPDH1Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. (601 aa)
CTSZCathepsin Z; Belongs to the peptidase C1 family. (368 aa)
F13A1Coagulation factor XIII A chain. (732 aa)
VPS13AVacuolar protein sorting-associated protein 13A; May play a role in the control of protein cycling through the trans-Golgi network to early and late endosomes, lysosomes and plasma membrane. (3418 aa)
FERMT3Fermitin family member 3. (664 aa)
ENSMFAP00000008901Peptidase_M24 domain-containing protein. (251 aa)
DERADeoxyribose-phosphate aldolase. (318 aa)
PYGLAlpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (847 aa)
CRISPLD2Cysteine rich secretory protein LCCL domain containing 2. (497 aa)
ACTR10Actin related protein 10; Belongs to the actin family. (417 aa)
ENSMFAP00000011440Protein S100; Belongs to the S-100 family. (105 aa)
TOR4ATorsin family 4 member A. (423 aa)
GGHFolate gamma-glutamyl hydrolase. (318 aa)
ALOX5Arachidonate 5-lipoxygenase. (674 aa)
SPACA7Sperm acrosome associated 7. (210 aa)
ENSMFAP00000012490Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (289 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
ENSMFAP00000012889Peptidase_M24 domain-containing protein. (244 aa)
ENSMFAP00000012946Protein S100; Belongs to the S-100 family. (104 aa)
LCN2Lipocalin 2; Belongs to the calycin superfamily. Lipocalin family. (198 aa)
ENSMFAP00000013449Protein S100; Belongs to the S-100 family. (105 aa)
ACTR1BActin related protein 1B. (376 aa)
VCPValosin containing protein; Belongs to the AAA ATPase family. (806 aa)
ENSMFAP00000014245Peptidase_M24 domain-containing protein. (368 aa)
KPNB1Karyopherin subunit beta 1. (875 aa)
MPOMyeloperoxidase. (745 aa)
ENSMFAP00000014556V-SNARE domain-containing protein. (198 aa)
HPSEHeparanase. (545 aa)
ENSMFAP00000015967Peptidase_M24 domain-containing protein. (353 aa)
PRSS57Serine protease 57; Belongs to the peptidase S1 family. (256 aa)
TOLLIPToll interacting protein. (274 aa)
PPBPC-X-C motif chemokine. (128 aa)
TIMP2TIMP metallopeptidase inhibitor 2. (188 aa)
LRRC7Leucine rich repeat containing 7. (1542 aa)
PDGFBPlatelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (241 aa)
PENKProenkephalin. (267 aa)
ENSMFAP00000017173PDZ domain-containing protein. (255 aa)
SCG3Secretogranin III. (468 aa)
SERPINI1Serpin family I member 1; Belongs to the serpin family. (410 aa)
PSMD13PCI domain-containing protein. (399 aa)
PF4C-X-C motif chemokine. (101 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
DBNLUncharacterized protein. (419 aa)
ENSMFAP00000018989Ku domain-containing protein. (498 aa)
GLAAlpha-galactosidase. (429 aa)
HRGHistidine rich glycoprotein. (525 aa)
MMP8Matrix metallopeptidase 8. (467 aa)
ENSMFAP00000019661Glia maturation factor; Belongs to the actin-binding proteins ADF family. GMF subfamily. (132 aa)
VTI1BVesicle transport through interaction with t-SNAREs 1B. (232 aa)
PCSK1Proprotein convertase subtilisin/kexin type 1; Belongs to the peptidase S8 family. (749 aa)
THBS1Thrombospondin 1. (1173 aa)
S100A12S100 calcium binding protein A12. (76 aa)
OSCAROsteoclast associated Ig-like receptor. (238 aa)
PYCARDPYD and CARD domain containing. (195 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (623 aa)
DYNLT1Dynein light chain Tctex-type 1. (113 aa)
ENSMFAP00000021023Ku domain-containing protein. (583 aa)
ENSMFAP00000021666EF-hand domain-containing protein; Belongs to the S-100 family. (107 aa)
BPIBactericidal permeability increasing protein. (511 aa)
DYNC1H1Dynein cytoplasmic 1 heavy chain 1. (4624 aa)
ENSMFAP00000023104IMPDH domain-containing protein. (358 aa)
FABP5FABP domain-containing protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (135 aa)
GAS6Growth arrest specific 6. (657 aa)
GHRLGhrelin and obestatin prepropeptide. (117 aa)
AGLAmylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase. (1532 aa)
CANT1Calcium activated nucleotidase 1. (401 aa)
OSTF1Osteoclast stimulating factor 1. (214 aa)
FOLR3Folate receptor gamma. (238 aa)
ENSMFAP00000025331Uncharacterized protein. (259 aa)
SPTAN1Spectrin alpha, non-erythrocytic 1. (2498 aa)
ACAA1Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (424 aa)
SPP2Secreted phosphoprotein 2. (211 aa)
AOC1Amine oxidase. (755 aa)
VEGFBVascular endothelial growth factor B; Belongs to the PDGF/VEGF growth factor family. (207 aa)
IGF2Insulin like growth factor 2. (183 aa)
C3Complement C3. (1663 aa)
IMPDH2Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. (514 aa)
VCLUncharacterized protein. (80 aa)
S100A9Protein S100; Belongs to the S-100 family. (114 aa)
FGBFibrinogen beta chain. (491 aa)
FGAFibrinogen alpha chain. (928 aa)
ENSMFAP00000027831Uncharacterized protein. (114 aa)
CREG1Cellular repressor of E1A stimulated genes 1; Belongs to the CREG family. (220 aa)
C1orf35Chromosome 1 open reading frame 35. (262 aa)
ARG1Arginase. (322 aa)
CHIT1Chitinase 1; Belongs to the glycosyl hydrolase 18 family. (466 aa)
LRG1Leucine rich alpha-2-glycoprotein 1. (347 aa)
CLUClusterin; Belongs to the clusterin family. (501 aa)
ENSMFAP00000028786FABP domain-containing protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (143 aa)
ACTN2Actinin alpha 2. (894 aa)
GALNSGalactosamine (N-acetyl)-6-sulfatase. (522 aa)
S100PS100 calcium binding protein P. (95 aa)
DPP7Dipeptidyl peptidase 7. (498 aa)
FAM49BFamily with sequence similarity 49 member B. (365 aa)
PDXKPyridoxal kinase. (312 aa)
PA2G4Proliferation-associated 2G4. (394 aa)
GMFBGlia maturation factor; Belongs to the actin-binding proteins ADF family. GMF subfamily. (155 aa)
VEGFDVascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. (353 aa)
CLEC3BC-type lectin domain family 3 member B. (202 aa)
GMFGGlia maturation factor; Belongs to the actin-binding proteins ADF family. GMF subfamily. (142 aa)
TXNDC5Thioredoxin domain containing 5; Belongs to the protein disulfide isomerase family. (431 aa)
ENSMFAP00000032355Uncharacterized protein. (310 aa)
IMPDHInosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. (489 aa)
VAT1PKS_ER domain-containing protein. (392 aa)
RAB27ARAB27A, member RAS oncogene family. (221 aa)
AMPD3AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (776 aa)
COMMD9COMM domain containing 9. (198 aa)
XRCC6Testis cDNA, clone: QtsA-19002, similar to human thyroid autoantigen 70kDa (Ku antigen) (G22P1). (609 aa)
AZU1Azurocidin 1. (250 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1208 aa)
VEGFCVascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (420 aa)
DSN1DSN1 component of MIS12 kinetochore complex. (354 aa)
GRPGastrin releasing peptide. (100 aa)
PSMC3AAA domain-containing protein; Belongs to the AAA ATPase family. (451 aa)
HEXBBeta-hexosaminidase. (557 aa)
ARSBArylsulfatase B. (534 aa)
PTX3Pentraxin 3. (381 aa)
JUPJunction plakoglobin. (745 aa)
DNAJC3DnaJ heat shock protein family (Hsp40) member C3. (504 aa)
HGFHepatocyte growth factor; Belongs to the peptidase S1 family. (788 aa)
HSPA6Heat shock protein family A (Hsp70) member 6; Belongs to the heat shock protein 70 family. (600 aa)
FGRTyrosine-protein kinase. (529 aa)
CRISP3Cysteine rich secretory protein 3; Belongs to the CRISP family. (245 aa)
SDCBPUncharacterized protein. (324 aa)
QPCTGlutaminyl-peptide cyclotransferase. (361 aa)
LTFLactotransferrin; Belongs to the transferrin family. (710 aa)
ITIH4Inter-alpha-trypsin inhibitor heavy chain 4. (935 aa)
STK11IPSerine/threonine kinase 11 interacting protein. (1088 aa)
PRTN3Proteinase 3; Belongs to the peptidase S1 family. (258 aa)
SPARCSecreted protein acidic and cysteine rich. (303 aa)
CYFIP1Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1232 aa)
TCN1Transcobalamin 1. (434 aa)
RETNUncharacterized protein. (65 aa)
SERPINF2Serpin family F member 2; Belongs to the serpin family. (491 aa)
DNASE1L1Deoxyribonuclease 1 like 1. (310 aa)
ORM1Orosomucoid 1. (180 aa)
CEP290Centrosomal protein 290. (2461 aa)
PSMD7Proteasome 26S subunit, non-ATPase 7. (322 aa)
ERP44Thioredoxin domain-containing protein. (414 aa)
ENSMFAP00000039848MPN domain-containing protein. (149 aa)
NEU1Neuraminidase 1. (416 aa)
GSNGelsolin. (784 aa)
BIN2Bridging integrator 2. (595 aa)
FAF2Fas associated factor family member 2. (445 aa)
HEBP2Heme binding protein 2. (205 aa)
KNG1Kininogen 1. (644 aa)
COTL1Coactosin like F-actin binding protein 1. (142 aa)
ARSAArylsulfatase A. (599 aa)
DBHDopamine beta-hydroxylase. (620 aa)
GCGGlucagon. (180 aa)
ELANEElastase, neutrophil expressed; Belongs to the peptidase S1 family. (264 aa)
PCYOX1LPrenylcysteine oxidase 1 like. (494 aa)
PSMD11Proteasome 26S subunit, non-ATPase 11. (422 aa)
F8Coagulation factor VIII; Belongs to the multicopper oxidase family. (2351 aa)
GYG1Uncharacterized protein. (354 aa)
ECM1Extracellular matrix protein 1. (540 aa)
NAPRTNicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (543 aa)
A1BGAlpha-1-B glycoprotein. (339 aa)
ENSMFAP00000043886Uncharacterized protein. (428 aa)
XRCC5X-ray repair cross complementing 5. (820 aa)
PSMB1Proteasome subunit beta. (241 aa)
APAF1Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1248 aa)
PRG3Proteoglycan 3, pro eosinophil major basic protein 2. (225 aa)
VWFVon Willebrand factor. (2813 aa)
S100A8Protein S100; Belongs to the S-100 family. (93 aa)
ALADDelta-aminolevulinic acid dehydratase; Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen (By similarity); Belongs to the ALAD family. (339 aa)
ARHGAP9Rho GTPase activating protein 9. (824 aa)
CFDComplement factor D; Belongs to the peptidase S1 family. (253 aa)
SERPINE1Serpin family E member 1; Belongs to the serpin family. (402 aa)
PNPPurine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (289 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
CAB39Calcium binding protein 39. (341 aa)
DOCK2Dedicator of cytokinesis 2; Belongs to the DOCK family. (1725 aa)
FRKTyrosine-protein kinase. (529 aa)
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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