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| | CACNA1G | Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2377 aa) |
| | STOML2 | Stomatin-like protein 2. (356 aa) |
| | MCOLN2 | Mucolipin 2. (586 aa) |
| | AFG3L2 | AFG3 like matrix AAA peptidase subunit 2. (800 aa) |
| | CALCRL | Calcitonin receptor like receptor; Belongs to the G-protein coupled receptor 2 family. (472 aa) |
| | FKBP1B | Peptidylprolyl isomerase. (108 aa) |
| | ORAI2 | ORAI calcium release-activated calcium modulator 2. (261 aa) |
| | ENSMMUP00000073505 | Uncharacterized protein. (391 aa) |
| | CACHD1 | Cache domain containing 1. (1310 aa) |
| | CACNA2D3 | Calcium voltage-gated channel auxiliary subunit alpha2delta 3. (1108 aa) |
| | CCR1 | C-C chemokine receptor type 1; Receptor for a C-C type chemokine. Binds to MIP-1-alpha, RANTES, MCP-3 and, less efficiently, to MIP-1-beta or MCP-1 and subsequently transduces a signal by increasing the intracellular calcium ions level. Responsible for affecting stem cell proliferation. (355 aa) |
| | CRACR2A | Calcium release activated channel regulator 2A. (731 aa) |
| | TPCN2 | Two pore segment channel 2. (823 aa) |
| | TMEM38A | Transmembrane protein 38A. (352 aa) |
| | GRIN2C | Glutamate ionotropic receptor NMDA type subunit 2C. (1317 aa) |
| | NOL3 | Nucleolar protein 3. (206 aa) |
| | ANO6 | Anoctamin. (933 aa) |
| | RAMP1 | Uncharacterized protein. (204 aa) |
| | CCL21 | C-C motif chemokine 21; Inhibits hemopoiesis and stimulates chemotaxis. Chemotactic in vitro for thymocytes and activated T-cells, but not for B-cells, macrophages, or neutrophils. Shows preferential activity towards naive T-cells. May play a role in mediating homing of lymphocytes to secondary lymphoid organs. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4 (By similarity). (131 aa) |
| | MICU2 | Mitochondrial calcium uptake 2. (456 aa) |
| | DDIT3 | DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (192 aa) |
| | CNR1 | Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids, including endocannabinoids (eCBs), such as N-arachidonoylethanolamide (also called anandamide or AEA) and 2-arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP (By similarity). In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. In [...] (472 aa) |
| | BCL2 | BCL2 apoptosis regulator. (241 aa) |
| | BSPRY | B-box and SPRY domain containing. (451 aa) |
| | TMEM37 | Transmembrane protein 37. (197 aa) |
| | RAMP3 | Uncharacterized protein. (172 aa) |
| | CACNG4 | Uncharacterized protein. (657 aa) |
| | TRPC4AP | Transient receptor potential cation channel subfamily C member 4 associated protein. (822 aa) |
| | SH2B1 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1087 aa) |
| | SLC8A3 | Solute carrier family 8 member A3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (928 aa) |
| | BAK1 | Uncharacterized protein. (261 aa) |
| | JPH3 | Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (748 aa) |
| | MS4A1 | Membrane spanning 4-domains A1. (297 aa) |
| | CCL3 | C-C motif chemokine 3; Monokine with inflammatory and chemokinetic properties. Binds to CCR1, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-alpha induces a dose- dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV) (By similarity). (92 aa) |
| | HTR2C | 5-hydroxytryptamine receptor 2C. (458 aa) |
| | ORAI3 | Protein orai-3. (295 aa) |
| | EPM2A | EPM2A glucan phosphatase, laforin. (331 aa) |
| | RASA3 | RAS p21 protein activator 3. (1098 aa) |
| | CACNG5 | Calcium voltage-gated channel auxiliary subunit gamma 5. (275 aa) |
| | LOC114675515 | Uncharacterized protein. (152 aa) |
| | ALX1 | Leucine rich repeats and IQ motif containing 1. (1898 aa) |
| | MCUR1 | Mitochondrial calcium uniporter regulator 1. (402 aa) |
| | GP9 | Uncharacterized protein. (246 aa) |
| | PKDREJ | Polycystin family receptor for egg jelly. (2251 aa) |
| | EDN1 | Preproendothelin-1. (211 aa) |
| | SLC25A23 | Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (501 aa) |
| | PRKCB | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa) |
| | CAV3 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (196 aa) |
| | CASR | Calcium sensing receptor. (1078 aa) |
| | CORO1A | Coronin; Belongs to the WD repeat coronin family. (461 aa) |
| | NMUR1 | Neuromedin U receptor 1; Belongs to the G-protein coupled receptor 1 family. (426 aa) |
| | PPP3CA | Serine/threonine-protein phosphatase. (547 aa) |
| | ENSMMUP00000057488 | Uncharacterized protein. (76 aa) |
| | P2RX4 | P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (467 aa) |
| | MRLN | Uncharacterized protein. (46 aa) |
| | TRPV4 | Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (963 aa) |
| | CACNA1H | Calcium voltage-gated channel subunit alpha1 H. (2352 aa) |
| | ENSMMUP00000056331 | XRCC1_N domain-containing protein. (403 aa) |
| | LOC100426537 | C-C motif chemokine. (67 aa) |
| | CCR7 | C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. (378 aa) |
| | RAMP2 | Receptor activity-modifying protein 2. (175 aa) |
| | TMEM38B | Trimeric intracellular cation channel type B. (291 aa) |
| | NCS1 | EF-hand domain-containing protein. (277 aa) |
| | RYR3 | Ryanodine receptor 3. (4870 aa) |
| | F2R | Coagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family. (425 aa) |
| | TRPM4 | Transient receptor potential cation channel subfamily M member 4. (1215 aa) |
| | ADRA1A | Adrenoceptor alpha 1A. (445 aa) |
| | PTPRC | Protein tyrosine phosphatase receptor type C. (1310 aa) |
| | TPT1 | TCTP domain-containing protein; Belongs to the TCTP family. (196 aa) |
| | SLC8A2 | Solute carrier family 8 member A2; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (921 aa) |
| | CACNA2D1 | Calcium voltage-gated channel auxiliary subunit alpha2delta 1. (1103 aa) |
| | CASK | Calcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family. (926 aa) |
| | ATP2C2 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (975 aa) |
| | EDNRB | Endothelin receptor type B; Belongs to the G-protein coupled receptor 1 family. (527 aa) |
| | GCK | Phosphotransferase. (466 aa) |
| | GRIN3B | Glutamate ionotropic receptor NMDA type subunit 3B; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1042 aa) |
| | CACNA1D | Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2181 aa) |
| | BBC3 | BCL2 binding component 3. (261 aa) |
| | ASPH | Aspartate beta-hydroxylase. (756 aa) |
| | GJA4 | Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (333 aa) |
| | ORAI1 | ORAI calcium release-activated calcium modulator 1. (301 aa) |
| | TRPC6 | Transient receptor potential cation channel subfamily C member 6; Belongs to the transient receptor (TC 1.A.4) family. (931 aa) |
| | CACNG6 | Voltage-dependent calcium channel gamma-6 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (261 aa) |
| | TRPA1 | Transient receptor potential cation channel subfamily A member 1; Belongs to the transient receptor (TC 1.A.4) family. (1144 aa) |
| | TRPM8 | Transient receptor potential cation channel subfamily M member 8. (1104 aa) |
| | ERO1A | Endoplasmic reticulum oxidoreductase 1 alpha. (647 aa) |
| | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1 isoform 3. (2758 aa) |
| | CRACR2B | Calcium release activated channel regulator 2B. (400 aa) |
| | SLC8B1 | Solute carrier family 8 member B1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (584 aa) |
| | GP1BA | Glycoprotein Ib platelet subunit alpha. (754 aa) |
| | PKD1 | Polycystin 1, transient receptor potential channel interacting. (4298 aa) |
| | RYR1 | Ryanodine receptor 1. (4928 aa) |
| | CACNG1 | Voltage-dependent calcium channel gamma-1 subunit; Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics. (222 aa) |
| | CACNA1A | Voltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents. (2411 aa) |
| | CHRNA10 | Cholinergic receptor nicotinic alpha 10 subunit. (450 aa) |
| | STIM1 | Stromal interaction molecule 1. (684 aa) |
| | TRPM2 | Transient receptor potential cation channel subfamily M member 2. (1539 aa) |
| | CNR2 | Cannabinoid receptor 2; Belongs to the G-protein coupled receptor 1 family. (360 aa) |
| | TPCN1 | Two pore segment channel 1. (888 aa) |
| | PANX1 | Pannexin; Structural component of the gap junctions and the hemichannels; Belongs to the pannexin family. (470 aa) |
| | TRPM5 | Transient receptor potential cation channel subfamily M member 5. (1156 aa) |
| | WNT3A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa) |
| | NEK11 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (955 aa) |
| | CATSPER3 | Cation channel sperm associated 3. (398 aa) |
| | PLCG2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa) |
| | MCOLN3 | Mucolipin 3. (553 aa) |
| | TMCO1 | Calcium load-activated calcium channel; Calcium-selective channel required to prevent calcium stores from overfilling; Belongs to the TMCO1 family. (188 aa) |
| | GRIN2D | Glutamate ionotropic receptor NMDA type subunit 2D. (1336 aa) |
| | TRPM3 | Transient receptor potential cation channel subfamily M member 3. (1707 aa) |
| | FAM155B | Family with sequence similarity 155 member B. (480 aa) |
| | ASIC1 | Amiloride-sensitive cation channel 2, neuronal isoform b; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (528 aa) |
| | VDR | Vitamin D receptor. (477 aa) |
| | CLCA1 | Calcium-activated chloride channel regulator 1; May be involved in mediating calcium-activated chloride conductance. May play critical roles in goblet cell metaplasia, mucus hypersecretion, cystic fibrosis and AHR. May be involved in the regulation of mucus production and/or secretion by goblet cells. Involved in the regulation of tissue inflammation in the innate immune response. May play a role as a tumor suppressor. Induces MUC5AC (By similarity). (1071 aa) |
| | CACNA2D2 | Calcium voltage-gated channel auxiliary subunit alpha2delta 2. (1153 aa) |
| | HUS1 | Uncharacterized protein. (2824 aa) |
| | FASLG | Tumor necrosis factor ligand superfamily member 6, membrane form; Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. Involved in cytotoxic T- cell-mediated apoptosis, natural killer cell-mediated apoptosis and in T-cell development. Initiates fratricidal/suicidal activation-induced cell death (AICD) in antigen-activated T-cells contributing to the termination of immune responses. TNFRSF6/FAS-mediated apoptosis has also a role in the induction of peripheral tolerance. Binds to TNFRSF6B/DcR3, a decoy receptor that blocks apoptosis. [FasL intr [...] (280 aa) |
| | CACNB2 | SH3 domain-containing protein. (660 aa) |
| | CACNG7 | Voltage-dependent calcium channel gamma-7 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (275 aa) |
| | TRPV5 | Transient receptor potential cation channel subfamily V member 5; Belongs to the transient receptor (TC 1.A.4) family. (729 aa) |
| | MCUB | Mitochondrial calcium uniporter dominant negative beta subunit. (336 aa) |
| | ATP2A3 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1092 aa) |
| | CACNA1F | Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1970 aa) |
| | PKD2 | Polycystin 2, transient receptor potential cation channel. (969 aa) |
| | CACNA1B | Voltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. (2338 aa) |
| | TRDN | Triadin. (725 aa) |
| | CCL8 | C-C motif chemokine. (109 aa) |
| | MARCKSL1 | MARCKS-related protein. (195 aa) |
| | TRPC5 | Transient receptor potential cation channel subfamily C member 5; Belongs to the transient receptor (TC 1.A.4) family. (974 aa) |
| | CACNB4 | SH3 domain-containing protein. (520 aa) |
| | IBTK | Inhibitor of Bruton tyrosine kinase. (1352 aa) |
| | PKD2L1 | Polycystin 2 like 1, transient receptor potential cation channel. (804 aa) |
| | MCOLN1 | Mucolipin 1. (710 aa) |
| | ATP2B3 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1220 aa) |
| | HTR2B | 5-hydroxytryptamine receptor 2B. (481 aa) |
| | TRPC1 | Transient receptor potential cation channel subfamily C member 1; Belongs to the transient receptor (TC 1.A.4) family. (834 aa) |
| | TMC1 | Transmembrane channel-like protein. (760 aa) |
| | CDH23 | Cadherin related 23. (3354 aa) |
| | CACNA1C | Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2186 aa) |
| | SMDT1 | Single-pass membrane protein with aspartate rich tail 1. (107 aa) |
| | TRPM6 | Transient receptor potential cation channel subfamily M member 6. (2025 aa) |
| | CYSLTR1 | Cysteinyl leukotriene receptor 1. (337 aa) |
| | CACNG3 | Calcium voltage-gated channel auxiliary subunit gamma 3. (315 aa) |
| | DNM1L | Dynamin 1 like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (802 aa) |
| | FLNA | Filamin-A isoform 2. (2647 aa) |
| | NMUR2 | Neuromedin U receptor 2; Belongs to the G-protein coupled receptor 1 family. (414 aa) |
| | TMC2 | Transmembrane channel-like protein. (905 aa) |
| | SLC24A4 | Solute carrier family 24 member 4; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (622 aa) |
| | CAV1 | Caveolin 1. (303 aa) |
| | SARAF | Store-operated calcium entry associated regulatory factor. (339 aa) |
| | CACNA1E | Voltage-dependent R-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents. (2412 aa) |
| | SLC8A1 | J domain-containing protein; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (973 aa) |
| | TRPV2 | Transient receptor potential cation channel subfamily V member 2; Belongs to the transient receptor (TC 1.A.4) family. (764 aa) |
| | NALCN | Sodium leak channel non-selective protein. (1738 aa) |
| | TRPV6 | Transient receptor potential cation channel subfamily V member 6; Belongs to the transient receptor (TC 1.A.4) family. (821 aa) |
| | JPH2 | Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (696 aa) |
| | CCL19 | C-C motif chemokine. (98 aa) |
| | GRIN3A | Glutamate ionotropic receptor NMDA type subunit 3A. (1115 aa) |
| | PKD1L3 | Polycystin 1 like 3, transient receptor potential channel interacting. (1721 aa) |
| | MICU1 | Uncharacterized protein. (482 aa) |
| | CACNA2D4 | Calcium voltage-gated channel auxiliary subunit alpha2delta 4. (1137 aa) |
| | CACNA1S | Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1873 aa) |
| | SEC61A1 | Protein transport protein Sec61 subunit alpha isoform 1. (476 aa) |
| | SLC24A5 | Solute carrier family 24 member 5; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (500 aa) |
| | EFHB | EF-hand domain family member B. (812 aa) |
| | GRIN2B | Glutamate ionotropic receptor NMDA type subunit 2B. (1484 aa) |
| | ITGAV | Integrin_alpha2 domain-containing protein; Belongs to the integrin alpha chain family. (1051 aa) |
| | ATP2B2 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1243 aa) |
| | LETM1 | Leucine zipper and EF-hand containing transmembrane protein 1. (728 aa) |
| | SLC3A2 | 4F2 cell-surface antigen heavy chain isoform c. (630 aa) |
| | MCU | Mitochondrial calcium uniporter. (351 aa) |
| | NOS3 | Nitric oxide synthase; Produces nitric oxide (NO). (1205 aa) |
| | CDK5 | Cyclin dependent kinase 5. (364 aa) |
| | CAMK2G | Calcium/calmodulin dependent protein kinase II gamma. (735 aa) |
| | LOC114673087 | C-C motif chemokine. (67 aa) |
| | SLC24A1 | Solute carrier family 24 member 1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (1093 aa) |
| | MAIP1 | Uncharacterized protein. (291 aa) |
| | SRI | Sorcin isoform a. (198 aa) |
| | CHRNA7 | Neuronal acetylcholine receptor subunit alpha-7; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is blocked by alpha-bungarotoxin (By similarity). (502 aa) |
| | PLCZ1 | Phosphoinositide phospholipase C. (608 aa) |
| | CYP27B1 | Uncharacterized protein; Belongs to the cytochrome P450 family. (508 aa) |
| | OPRM1 | Mu-type opioid receptor; Receptor for endogenous opioids such as beta-endorphin and endomorphin. Receptor for natural and synthetic opioids including morphine, heroin, DAMGO, fentanyl, etorphine, buprenorphin and methadone. Agonist binding to the receptor induces coupling to an inactive GDP-bound heterotrimeric G-protein complex and subsequent exchange of GDP for GTP in the G-protein alpha subunit leading to dissociation of the G-protein complex with the free GTP-bound G-protein alpha and the G-protein beta-gamma dimer activating downstream cellular effectors. The agonist- and cell typ [...] (400 aa) |
| | ITPR3 | Inositol 1,4,5-trisphosphate receptor type 3. (2671 aa) |
| | ZMPSTE24 | CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (475 aa) |
| | KCNN4 | Potassium calcium-activated channel subfamily N member 4. (427 aa) |
| | GP1BB | Glycoprotein Ib platelet subunit beta. (208 aa) |
| | CATSPER4 | Cation channel sperm associated 4. (472 aa) |
| | GRIN1 | Glutamate ionotropic receptor NMDA type subunit 1. (943 aa) |
| | ITPR2 | Inositol 1,4,5-trisphosphate receptor type 2. (2700 aa) |
| | SLC25A25 | Solute carrier family 25 member 25; Belongs to the mitochondrial carrier (TC 2.A.29) family. (514 aa) |
| | P2RX7 | P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (573 aa) |
| | CACNG2 | Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (323 aa) |
| | CACNA1I | Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2111 aa) |
| | HTR2A | 5-hydroxytryptamine receptor 2A; G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances, including mescaline, psilocybin, 1-(2,5- dimethoxy-4-iodophenyl)-2-aminopropane (DOI) and lysergic acid diethylamide (LSD). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. S [...] (471 aa) |
| | FAM155A | Family with sequence similarity 155 member A. (457 aa) |
| | TRPV1 | Transient receptor potential cation channel subfamily V member 1; Belongs to the transient receptor (TC 1.A.4) family. (839 aa) |
| | STIM2 | Stromal interaction molecule 2. (840 aa) |
| | CHRNA9 | Cholinergic receptor nicotinic alpha 9 subunit. (479 aa) |
| | CSN2 | Beta-casein; Important role in determination of the surface properties of the casein micelles. (226 aa) |
| | ANK2 | Ankyrin 2. (4045 aa) |
| | TRPC3 | Transient receptor potential cation channel subfamily C member 3; Belongs to the transient receptor (TC 1.A.4) family. (921 aa) |
| | EDNRA | Uncharacterized protein; Belongs to the G-protein coupled receptor 1 family. (427 aa) |
| | MYOT | Polycystin 2 like 2, transient receptor potential cation channel. (851 aa) |
| | PSEN1 | Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (463 aa) |
| | TSPOAP1 | TSPO associated protein 1. (1936 aa) |
| | CACNB3 | SH3 domain-containing protein. (498 aa) |
| | GRIN2A | Glutamate ionotropic receptor NMDA type subunit 2A. (1464 aa) |
| | CACNG8 | Voltage-dependent calcium channel gamma-8 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (387 aa) |
| | TRPM1 | Transient receptor potential cation channel subfamily M member 1. (1642 aa) |
| | SLC24A3 | Solute carrier family 24 member 3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (644 aa) |
| | CCN2 | Cellular communication network factor 2. (349 aa) |
| | SLC35G1 | Solute carrier family 35 member G1. (363 aa) |
| | TMEM165 | GDT1 family protein. (329 aa) |
| | CATSPER2 | Cation channel sperm-associated protein 2 isoform 4. (199 aa) |
| | RYR2 | Ryanodine receptor 2. (4967 aa) |
| | LOC715292 | VWFA domain-containing protein. (944 aa) |
| | LOC715685 | Uncharacterized protein. (542 aa) |
| | TRPC7 | Transient receptor potential cation channel subfamily C member 7; Belongs to the transient receptor (TC 1.A.4) family. (862 aa) |
| | CACNB1 | Calcium voltage-gated channel auxiliary subunit beta 1. (643 aa) |
| | TRPC4 | ANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family. (977 aa) |
| | ANXA6 | Annexin. (673 aa) |
| | LCK | Tyrosine-protein kinase. (567 aa) |
| | TRPV3 | Transient receptor potential cation channel subfamily V member 3; Belongs to the transient receptor (TC 1.A.4) family. (790 aa) |
| | JPH4 | Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (628 aa) |
| | CHRNB2 | Neuronal acetylcholine receptor subunit beta-2. (502 aa) |
| | TRPM7 | Transient receptor potential cation channel subfamily M member 7. (2379 aa) |
| | SLC24A2 | Solute carrier family 24 member 2; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (709 aa) |
| | FYN | Tyrosine-protein kinase. (589 aa) |
| | CHERP | Calcium homeostasis endoplasmic reticulum protein. (927 aa) |
| | GAS6 | Growth arrest specific 6. (684 aa) |
| | CATSPER1 | Cation channel sperm associated 1. (798 aa) |
| | ATP2B4 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1205 aa) |
| | LOC114675624 | Uncharacterized protein; Belongs to the MAGUK family. (450 aa) |
| | CALHM1 | Calcium homeostasis modulator 1. (345 aa) |
| | SELENOK | Selenoprotein K. (91 aa) |
| | JPH1 | Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (661 aa) |
| | MICU3 | Mitochondrial calcium uptake family member 3. (530 aa) |
| | ATP2A2 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1011 aa) |
| | ATP2B1 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1249 aa) |
| | ANXA9 | Annexin. (345 aa) |
