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| IL4 | Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4; Belongs to the IL- [...] (153 aa) | ||||
| CEBPB | CCAAT/enhancer-binding protein. (344 aa) | ||||
| GPER1 | G-protein coupled estrogen receptor 1; G-protein coupled estrogen receptor that binds to 17-beta- estradiol (E2) with high affinity, leading to rapid and transient activation of numerous intracellular signaling pathways. Stimulates cAMP production, calcium mobilization and tyrosine kinase Src inducing the release of heparin-bound epidermal growth factor (HB-EGF) and subsequent transactivation of the epidermal growth factor receptor (EGFR), activating downstream signaling pathways such as PI3K/Akt and ERK/MAPK. Mediates pleiotropic functions among others in the cardiovascular, endocrine [...] (375 aa) | ||||
| RABGEF1 | Uncharacterized protein. (492 aa) | ||||
| APOE | Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...] (317 aa) | ||||
| SCRIB | Scribble planar cell polarity protein. (1451 aa) | ||||
| GCLC | Glutamate--cysteine ligase catalytic subunit isoform a. (637 aa) | ||||
| FGL1 | Fibrinogen like 1. (312 aa) | ||||
| IRF1 | Interferon regulatory factor. (325 aa) | ||||
| TARM1 | T cell-interacting, activating receptor on myeloid cells 1. (281 aa) | ||||
| TNFAIP3 | Tumor necrosis factor alpha-induced protein 3. (790 aa) | ||||
| MILR1 | Mast cell immunoglobulin like receptor 1. (343 aa) | ||||
| AXL | AXL receptor tyrosine kinase. (894 aa) | ||||
| PLA2G2D | Phospholipase A(2). (161 aa) | ||||
| ZC3H8 | Zinc finger CCCH-type containing 8. (295 aa) | ||||
| BTK | Tyrosine-protein kinase. (659 aa) | ||||
| TNFRSF14 | TNF receptor superfamily member 14. (359 aa) | ||||
| CD274 | CD274 molecule. (299 aa) | ||||
| ZBTB7B | Zinc finger and BTB domain containing 7B. (636 aa) | ||||
| DLG1 | Disks large homolog 1 isoform 2; Belongs to the MAGUK family. (926 aa) | ||||
| SCGB1A1 | Secretoglobin family 1A member 1. (91 aa) | ||||
| NR1H3 | Nuclear receptor subfamily 1 group H member 3. (453 aa) | ||||
| LOXL3 | Lysyl oxidase like 3. (753 aa) | ||||
| LOC106993942 | Galectin. (356 aa) | ||||
| BANK1 | B cell scaffold protein with ankyrin repeats 1. (797 aa) | ||||
| HFE | Homeostatic iron regulator; Belongs to the MHC class I family. (348 aa) | ||||
| TREM2 | Triggering receptor expressed on myeloid cells 2. (291 aa) | ||||
| ADGRF5 | Adhesion G protein-coupled receptor F5; Belongs to the G-protein coupled receptor 2 family. (1383 aa) | ||||
| TNFRSF21 | Tumor necrosis factor receptor superfamily member 21. (655 aa) | ||||
| IDO1 | Indoleamine 2,3-dioxygenase 1. (403 aa) | ||||
| SFRP1 | Secreted frizzled-related protein 1. (314 aa) | ||||
| PGLYRP2 | Peptidoglycan recognition protein 2. (576 aa) | ||||
| SAMSN1 | Uncharacterized protein. (646 aa) | ||||
| GRN | Granulin precursor. (593 aa) | ||||
| TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa) | ||||
| IL10 | Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines in [...] (178 aa) | ||||
| LRRC32 | Leucine rich repeat containing 32. (662 aa) | ||||
| PARP3 | Poly [ADP-ribose] polymerase. (532 aa) | ||||
| FGG | Fibrinogen gamma chain. (437 aa) | ||||
| IL2 | Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells (By similarity); Belongs to the IL-2 family. (154 aa) | ||||
| NOS3 | Nitric oxide synthase; Produces nitric oxide (NO). (1205 aa) | ||||
| BPI | Bactericidal permeability increasing protein. (582 aa) | ||||
| H9H440_MACMU | MHC_I-like_Ag-recog domain-containing protein. (128 aa) | ||||
| BLK | Tyrosine-protein kinase. (568 aa) | ||||
| IFNB1 | Interferon beta 1. (187 aa) | ||||
| RAG2 | Recombination activating 2. (532 aa) | ||||
| LOC100427967 | Galectin. (355 aa) | ||||
| CLNK | Cytokine dependent hematopoietic cell linker. (443 aa) | ||||
| ENPP3 | Ectonucleotide pyrophosphatase/phosphodiesterase 3. (874 aa) | ||||
| TBC1D10C | Carabin. (446 aa) | ||||
| VTCN1 | V-set domain containing T cell activation inhibitor 1. (282 aa) | ||||
| THBD | Uncharacterized protein. (607 aa) | ||||
| ALOX12 | Arachidonate 12-lipoxygenase, 12S type. (663 aa) | ||||
| SPN | Sialophorin. (547 aa) | ||||
| CTLA4 | Cytotoxic T-lymphocyte protein 4 isoform CTLA4-TM. (223 aa) | ||||
| CD84 | CD84 molecule. (345 aa) | ||||
| PAWR | Pro-apoptotic WT1 regulator. (341 aa) | ||||
| CD37 | Tetraspanin. (281 aa) | ||||
| NRARP | Notch-regulated ankyrin repeat-containing protein. (114 aa) | ||||
| TYRO3 | Tyrosine-protein kinase receptor TYRO3. (890 aa) | ||||
| CR1 | Complement C3b/C4b receptor 1 (Knops blood group). (2041 aa) | ||||
| FER | Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa) | ||||
| ITCH | E3 ubiquitin-protein ligase. (918 aa) | ||||
| LRFN5 | Leucine rich repeat and fibronectin type III domain containing 5. (750 aa) | ||||
| IL4I1 | Amine oxidase. (589 aa) | ||||
| JAK3 | Janus kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. (602 aa) | ||||
| SOCS1 | Suppressor of cytokine signaling 1. (215 aa) | ||||
| IFNL1 | Interferon lambda 1. (202 aa) | ||||
| PRKG1 | cGMP-dependent protein kinase. (686 aa) | ||||
| ICOSLG | Uncharacterized protein. (305 aa) | ||||
| ZC3H12A | Zinc finger CCCH-type containing 12A. (601 aa) | ||||
| PTPN6 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (626 aa) | ||||
| GLMN | Glomulin, FKBP associated protein. (594 aa) | ||||
| MERTK | MER proto-oncogene, tyrosine kinase. (1232 aa) | ||||
| INPP5D | Inositol polyphosphate-5-phosphatase D. (1208 aa) | ||||
| BCR | BCR activator of RhoGEF and GTPase. (1271 aa) | ||||
| CD74 | HLA class II histocompatibility antigen gamma chain isoform a. (294 aa) | ||||
| TRIM2 | Transmembrane 131 like. (1724 aa) | ||||
| LST1 | Leukocyte-specific transcript 1 protein; Possible role in modulating immune responses. Has an inhibitory effect on lymphocyte proliferation. Induces morphological changes including production of filopodia and microspikes when overexpressed in a variety of cell types and may be involved in dendritic cell maturation (By similarity); Belongs to the LST1 family. (90 aa) | ||||
| MAMU-F | Mamu class I histocompatibility antigen, alpha chain F; Involved in the presentation of foreign antigens to the immune system. (348 aa) | ||||
| PGLYRP1 | Peptidoglycan-recognition protein; Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Involved in innate immunity. (196 aa) | ||||
| FOXP3 | Forkhead box P3. (539 aa) | ||||
| PTEN | Uncharacterized protein. (589 aa) | ||||
| INHA | Inhibin alpha chain; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition; Belongs to the TGF-beta family. (366 aa) | ||||
| IL20RB | Fibronectin type-III domain-containing protein. (311 aa) | ||||
| PDE5A | Phosphodiesterase. (875 aa) | ||||
| FBXO7 | F-box only protein 7 isoform 1. (522 aa) | ||||
| SERPINE2 | Serpin family E member 2; Belongs to the serpin family. (409 aa) | ||||
| CST7 | Cystatin-F. (145 aa) | ||||
| HAVCR2 | Hepatitis A virus cellular receptor 2. (294 aa) | ||||
| TNFRSF13B | TNF receptor superfamily member 13B. (293 aa) | ||||
| PDGFA | Platelet derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. (249 aa) | ||||
| THOC1 | THO complex subunit 1. (657 aa) | ||||
| HMGB3 | Uncharacterized protein. (201 aa) | ||||
| CD9 | Tetraspanin. (228 aa) | ||||
| CTSG | Cathepsin G; Belongs to the peptidase S1 family. (255 aa) | ||||
| ATM | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3056 aa) | ||||
| CD300LF | CD300 molecule like family member f. (306 aa) | ||||
| KLF5 | Uncharacterized protein. (1062 aa) | ||||
| UBASH3B | Ubiquitin-associated and SH3 domain-containing protein B. (649 aa) | ||||
| RASSF5 | Ras association domain family member 5. (418 aa) | ||||
| SH2B3 | SH2B adaptor protein 3. (570 aa) | ||||
| GIMAP5 | AIG1-type G domain-containing protein. (338 aa) | ||||
| ADAMTS18 | ADAM metallopeptidase with thrombospondin type 1 motif 18. (1221 aa) | ||||
| IHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (411 aa) | ||||
| RC3H1 | Ring finger and CCCH-type domains 1. (1133 aa) | ||||
| SOCS5 | Suppressor of cytokine signaling 5. (536 aa) | ||||
| BCL6 | Uncharacterized protein. (735 aa) | ||||
| TNFSF18 | Tumor necrosis factor ligand 2A. (199 aa) | ||||
| RHBDD3 | Rhomboid domain-containing protein 3. (386 aa) | ||||
| IL13RA2 | Interleukin 13 receptor subunit alpha 2. (388 aa) | ||||
| GPNMB | PKD domain-containing protein. (556 aa) | ||||
| DLG5 | Discs large MAGUK scaffold protein 5; Belongs to the MAGUK family. (1948 aa) | ||||
| HLX | H2.0 like homeobox. (495 aa) | ||||
| SOCS6 | Suppressor of cytokine signaling 6. (535 aa) | ||||
| TIGIT | T cell immunoreceptor with Ig and ITIM domains. (245 aa) | ||||
| NCKAP1L | NCK associated protein 1 like. (1134 aa) | ||||
| ENSMMUP00000077416 | Uncharacterized protein. (113 aa) | ||||
| BMP4 | Bone morphogenetic protein 4. (408 aa) | ||||
| TAFA3 | Uncharacterized protein. (227 aa) | ||||
| ARG2 | Arginase. (417 aa) | ||||
| INHBA | Inhibin subunit beta A. (426 aa) | ||||
| NDFIP1 | Uncharacterized protein. (228 aa) | ||||
| GAL | GALANIN domain-containing protein. (166 aa) | ||||
| LILRB4 | Leukocyte immunoglobulin like receptor B4. (423 aa) | ||||
| KHK | Elastin microfibril interfacer 1. (1016 aa) | ||||
| PRKCD | Protein kinase C. (729 aa) | ||||
| C1QTNF6 | C1q and TNF related 6. (278 aa) | ||||
| RUNX1 | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (480 aa) | ||||
| VSIG4 | V-set and immunoglobulin domain containing 4. (404 aa) | ||||
| ARG1 | Arginase. (322 aa) | ||||
| CD80 | CD80 molecule. (288 aa) | ||||
| TYROBP | TYRO protein tyrosine kinase-binding protein; Adapter protein which non-covalently associates with activating receptors found on the surface of a variety of immune cells to mediate signaling and cell activation following ligand binding by the receptors (By similarity). TYROBP is tyrosine-phosphorylated in the ITAM domain following ligand binding by the associated receptors which leads to activation of additional tyrosine kinases and subsequent cell activation (By similarity). Also has an inhibitory role in some cells (By similarity). Non-covalently associates with activating receptors [...] (241 aa) | ||||
| LOC705334 | Uncharacterized protein. (205 aa) | ||||
| LAX1 | Uncharacterized protein. (398 aa) | ||||
| CRTAM | Cytotoxic and regulatory T cell molecule. (401 aa) | ||||
| TWSG1 | Twisted gastrulation protein-like protein 1. (223 aa) | ||||
| LAG3 | Lymphocyte activating 3. (533 aa) | ||||
| PELI1 | E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (418 aa) | ||||
| CX3CL1 | C-X3-C motif chemokine ligand 1. (407 aa) | ||||
| CBLB | Cbl proto-oncogene B. (982 aa) | ||||
| ABAT | 4-aminobutyrate aminotransferase. (568 aa) | ||||
| MARCHF7 | Membrane associated ring-CH-type finger 7. (704 aa) | ||||
| FOXJ1 | Forkhead box J1. (421 aa) | ||||
| C1QTNF1 | C1q and TNF related 1. (423 aa) | ||||
| SDC4 | Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (198 aa) | ||||
| CBFB | Core-binding factor subunit beta isoform 1. (187 aa) | ||||
| CLEC4G | C-type lectin domain family 4 member G. (293 aa) | ||||
| PAG1 | Phosphoprotein membrane anchor with glycosphingolipid microdomains 1. (432 aa) | ||||
| ENSMMUP00000069441 | TACI-CRD2 domain-containing protein. (109 aa) | ||||
| IL4R | Interleukin 4 receptor. (825 aa) | ||||
| VSIR | V-set immunoregulatory receptor. (311 aa) | ||||
| GLI3 | GLI family zinc finger 3. (1580 aa) | ||||
| PDCD1LG2 | Programmed cell death 1 ligand 2. (273 aa) | ||||
| FGL2 | Fibrinogen like 2. (439 aa) | ||||
| PTPN2 | Tyrosine-protein phosphatase non-receptor type. (415 aa) | ||||
| PDGFB | Platelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (265 aa) | ||||
| FGR | Tyrosine-protein kinase. (529 aa) | ||||
| MAD1L1 | Mitotic arrest deficient 1 like 1. (718 aa) | ||||
| SHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (465 aa) | ||||
| NR1D1 | Nuclear receptor subfamily 1 group D member 1. (613 aa) | ||||
| LOC100426567 | Uncharacterized protein. (638 aa) | ||||
| PGLYRP3 | Peptidoglycan recognition protein 3. (341 aa) | ||||
| ZBTB46 | Zinc finger and BTB domain containing 46. (588 aa) | ||||
| ERBB2 | Receptor protein-tyrosine kinase. (1437 aa) | ||||
| PRNP | Major prion protein; Its primary physiological function is unclear. Has cytoprotective activity against internal or environmental stresses. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May play a role in iron uptake and iron homeostasis. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro). Association with GPC1 (via its heparan sulfate chains) targets PRNP to lipid rafts. Also provides Cu(2+) or ZN(2+) for the ascorbate-mediated GPC1 deaminase degradation of its heparan s [...] (253 aa) | ||||
| ANXA1 | Annexin. (367 aa) | ||||
| LGALS3 | Galectin. (248 aa) | ||||
| SMAD7 | Mothers against decapentaplegic homolog. (462 aa) | ||||
| FOXF1 | Forkhead box F1. (432 aa) | ||||
| LOC694781 | Galectin. (136 aa) | ||||
| TBX21 | T-box transcription factor 21. (539 aa) | ||||
| CEACAM1 | Uncharacterized protein. (525 aa) | ||||
| LOC114669853 | Tyrosine-protein kinase. (1125 aa) | ||||
| ILDR2 | Immunoglobulin like domain containing receptor 2. (643 aa) | ||||
| CD200 | Ig-like domain-containing protein. (300 aa) | ||||
| RUNX3 | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (428 aa) | ||||
| CYGB | GLOBIN domain-containing protein; Belongs to the globin family. (331 aa) | ||||
| LOC114674161 | Galectin. (136 aa) | ||||
| MDK | Midkine. (143 aa) | ||||
| RC3H2 | RING finger and CCCH-type zinc finger domain-containing protein 2 isoform 1. (1191 aa) | ||||
| ENSMMUP00000057803 | MHC_I-like_Ag-recog domain-containing protein. (216 aa) | ||||
| PKN1 | Protein kinase N1. (1013 aa) | ||||
| SOX11 | Transcription factor SOX. (441 aa) | ||||
| DUSP22 | Dual specificity phosphatase 22; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (279 aa) | ||||
| PTPRC | Protein tyrosine phosphatase receptor type C. (1310 aa) | ||||
| SYT11 | Synaptotagmin-11. (431 aa) | ||||
| LRRC1 | Leucine-rich repeat-containing protein 1. (524 aa) | ||||
| PTPN22 | Protein tyrosine phosphatase non-receptor type 22. (813 aa) | ||||
| LDLR | Uncharacterized protein. (918 aa) | ||||
| LYN | Tyrosine-protein kinase. (577 aa) | ||||
| CD86 | CD86 molecule. (417 aa) | ||||
| ENSMMUP00000051444 | Uncharacterized protein. (214 aa) | ||||
| TNFSF4 | Tumor necrosis factor ligand 2B; Belongs to the tumor necrosis factor family. (183 aa) | ||||