112 items (Macaca nemestrina) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MYOCD	Myocardin. (986 aa)
	HEXIM1	HEXIM P-TEFb complex subunit 1. (359 aa)
	PIK3CB	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1073 aa)
	LATS2	Non-specific serine/threonine protein kinase. (1086 aa)
	ENSMNEP00000000865	Uncharacterized protein. (124 aa)
	DAB2IP	DAB2 interacting protein. (1189 aa)
	PKIG	cAMP-dependent protein kinase inhibitor; Belongs to the PKI family. (76 aa)
	BMP7	Bone morphogenetic protein 7. (431 aa)
	CDKN1A	Cyclin dependent kinase inhibitor 1A. (164 aa)
	ENSMNEP00000002241	Uncharacterized protein. (481 aa)
	SPRY1	Sprouty RTK signaling antagonist 1. (319 aa)
	ENSMNEP00000004654	Uncharacterized protein. (58 aa)
	KAT2B	Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (800 aa)
	ENSMNEP00000006776	Uncharacterized protein. (243 aa)
	PTEN	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
	FBXO7	F-box protein 7. (522 aa)
	PAQR3	Progestin and adipoQ receptor family member 3. (311 aa)
	ABL1	Tyrosine-protein kinase. (1148 aa)
	DEFB114	Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family. (69 aa)
	ENSMNEP00000008233	Uncharacterized protein. (855 aa)
	SMPD1	Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (621 aa)
	GADD45A	Growth arrest and DNA damage inducible alpha. (165 aa)
	CDK5RAP3	CDK5 regulatory subunit associated protein 3. (541 aa)
	DUSP10	Dual specificity phosphatase 10. (488 aa)
	STK38	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (465 aa)
	NF1	Neurofibromin 1. (2839 aa)
	ENSMNEP00000010606	Uncharacterized protein. (337 aa)
	PRKAR2A	Protein kinase cAMP-dependent type II regulatory subunit alpha. (359 aa)
	RB1	RB transcriptional corepressor 1. (928 aa)
	PTPN22	Protein tyrosine phosphatase non-receptor type 22. (813 aa)
	ENSMNEP00000012244	Uncharacterized protein. (216 aa)
	HIPK3	Homeodomain interacting protein kinase 3. (1215 aa)
	TFAP4	Transcription factor AP-4. (338 aa)
	AGT	Angiotensinogen; Belongs to the serpin family. (485 aa)
	ENSMNEP00000012932	Uncharacterized protein. (343 aa)
	DNAJA1	DnaJ heat shock protein family (Hsp40) member A1. (397 aa)
	INCA1	Inhibitor of CDK, cyclin A1 interacting protein 1. (236 aa)
	BMP4	Bone morphogenetic protein 4. (408 aa)
	DUSP19	Dual specificity phosphatase 19; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (217 aa)
	CDKN1B	Cyclin dependent kinase inhibitor 1B. (198 aa)
	CDKN2C	Cyclin dependent kinase inhibitor 2C. (168 aa)
	MACROH2A1	Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. (372 aa)
	SH2B3	SH2B adaptor protein 3. (570 aa)
	HEXIM2	HEXIM P-TEFb complex subunit 2. (339 aa)
	ENSMNEP00000016961	J domain-containing protein. (219 aa)
	WEE2	Wee1-like protein kinase. (568 aa)
	IRAK3	Interleukin 1 receptor associated kinase 3. (596 aa)
	APOE	Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...] (317 aa)
	CDKN2D	Cyclin dependent kinase inhibitor 2D. (166 aa)
	RGS2	Regulator of G protein signaling 2. (211 aa)
	MEN1	Menin 1. (610 aa)
	TMEM130	Transmembrane protein 130. (413 aa)
	LRP6	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1613 aa)
	SIRT1	Sirtuin 1. (743 aa)
	IPO5	Importin 5. (1115 aa)
	IPO7	Importin 7. (1038 aa)
	INPP5K	Inositol polyphosphate-5-phosphatase K. (448 aa)
	ENSMNEP00000024043	Uncharacterized protein. (300 aa)
	ENSMNEP00000024166	Uncharacterized protein. (277 aa)
	HYAL2	Hyaluronidase. (473 aa)
	AIDA	Uncharacterized protein. (306 aa)
	NR2F2	Nuclear receptor subfamily 2 group F member 2. (414 aa)
	LAX1	Lymphocyte transmembrane adaptor 1. (398 aa)
	SPRY4	Sprouty RTK signaling antagonist 4. (322 aa)
	TNFAIP3	TNF alpha induced protein 3. (790 aa)
	AKT1	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
	PRKAG2	Protein kinase AMP-activated non-catalytic subunit gamma 2. (568 aa)
	PTPN6	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (623 aa)
	HEG1	Heart development protein with EGF like domains 1. (1346 aa)
	MAPK8IP1	Mitogen-activated protein kinase 8 interacting protein 1. (714 aa)
	SFRP2	Secreted frizzled related protein 2. (295 aa)
	PRKCD	Protein kinase C. (729 aa)
	PRKAR2B	Protein kinase cAMP-dependent type II regulatory subunit beta. (421 aa)
	CHORDC1	Cysteine and histidine rich domain containing 1. (332 aa)
	RGS14	Regulator of G protein signaling 14. (583 aa)
	CD300A	CD300a molecule. (296 aa)
	SLC8A3	Solute carrier family 8 member A3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (928 aa)
	TESK1	Testis associated actin remodelling kinase 1. (626 aa)
	SPRY2	Sprouty RTK signaling antagonist 2. (352 aa)
	PPP1R1B	Protein phosphatase 1 regulatory inhibitor subunit 1B. (204 aa)
	CDKN2B	Cyclin dependent kinase inhibitor 2B. (138 aa)
	PYCARD	PYD and CARD domain containing. (195 aa)
	PKIB	cAMP-dependent protein kinase inhibitor; Belongs to the PKI family. (85 aa)
	NUP62	Nucleoporin 62. (338 aa)
	PKIA	cAMP-dependent protein kinase inhibitor; Belongs to the PKI family. (76 aa)
	LYN	Tyrosine-protein kinase. (512 aa)
	DUSP7	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (368 aa)
	LATS1	Large tumor suppressor kinase 1. (1129 aa)
	ADIPOQ	Adiponectin, C1Q and collagen domain containing. (274 aa)
	DUSP1	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (367 aa)
	APC	APC regulator of WNT signaling pathway. (2864 aa)
	PLK1	Serine/threonine-protein kinase PLK. (603 aa)
	DUSP16	Dual specificity phosphatase 16. (668 aa)
	RASIP1	Ras interacting protein 1. (1064 aa)
	LRP5	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1599 aa)
	DTNBP1	Dystrobrevin binding protein 1. (350 aa)
	GSTP1	Glutathione S-transferase pi 1; Belongs to the GST superfamily. (210 aa)
	PTPRJ	Protein tyrosine phosphatase receptor type J. (1340 aa)
	CBLC	Cbl proto-oncogene C. (388 aa)
	CDKN2A	Cyclin dependent kinase inhibitor 2A. (160 aa)
	SORL1	Sortilin related receptor 1. (2184 aa)
	CAV1	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
	SLC8A1	Solute carrier family 8 member A1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (973 aa)
	CAV3	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
	CDK5RAP1	CDK5 regulatory subunit associated protein 1. (587 aa)
	SPRY3	Sprouty RTK signaling antagonist 3. (288 aa)
	PTPN1	Tyrosine-protein phosphatase non-receptor type. (435 aa)
	HHEX	Hematopoietically expressed homeobox. (270 aa)
	SFRP1	Secreted frizzled related protein 1. (314 aa)
	ENSMNEP00000027007	J domain-containing protein. (323 aa)
	NPPA	Natriuretic peptide A. (153 aa)
	BMP2	Bone morphogenetic protein 2. (396 aa)

Your Current Organism:

Macaca nemestrina

NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABL1	CBLC	ENSMNEP00000007383	ENSMNEP00000044171	Tyrosine-protein kinase.	Cbl proto-oncogene C.	0.586
ABL1	CDKN1A	ENSMNEP00000007383	ENSMNEP00000002098	Tyrosine-protein kinase.	Cyclin dependent kinase inhibitor 1A.	0.557
ABL1	RB1	ENSMNEP00000007383	ENSMNEP00000011939	Tyrosine-protein kinase.	RB transcriptional corepressor 1.	0.965
ADIPOQ	PAQR3	ENSMNEP00000040295	ENSMNEP00000007360	Adiponectin, C1Q and collagen domain containing.	Progestin and adipoQ receptor family member 3.	0.844
ADIPOQ	SIRT1	ENSMNEP00000040295	ENSMNEP00000021796	Adiponectin, C1Q and collagen domain containing.	Sirtuin 1.	0.556
AGT	APOE	ENSMNEP00000012667	ENSMNEP00000017988	Angiotensinogen; Belongs to the serpin family.	Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...]	0.424
AGT	NPPA	ENSMNEP00000012667	ENSMNEP00000026545	Angiotensinogen; Belongs to the serpin family.	Natriuretic peptide A.	0.515
AKT1	APOE	ENSMNEP00000026038	ENSMNEP00000017988	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...]	0.415
AKT1	CAV1	ENSMNEP00000026038	ENSMNEP00000044889	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.476
AKT1	CDKN1A	ENSMNEP00000026038	ENSMNEP00000002098	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Cyclin dependent kinase inhibitor 1A.	0.977
AKT1	CDKN1B	ENSMNEP00000026038	ENSMNEP00000015121	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Cyclin dependent kinase inhibitor 1B.	0.980
AKT1	ENSMNEP00000000865	ENSMNEP00000026038	ENSMNEP00000000865	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.518
AKT1	ENSMNEP00000012244	ENSMNEP00000026038	ENSMNEP00000012244	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.518
AKT1	LYN	ENSMNEP00000026038	ENSMNEP00000037491	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Tyrosine-protein kinase.	0.541
AKT1	PIK3CB	ENSMNEP00000026038	ENSMNEP00000000547	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family.	0.962
AKT1	PTEN	ENSMNEP00000026038	ENSMNEP00000006951	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	0.686
AKT1	SIRT1	ENSMNEP00000026038	ENSMNEP00000021796	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Sirtuin 1.	0.401
APC	LRP5	ENSMNEP00000042180	ENSMNEP00000042919	APC regulator of WNT signaling pathway.	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.	0.548
APC	LRP6	ENSMNEP00000042180	ENSMNEP00000021639	APC regulator of WNT signaling pathway.	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.	0.501
APC	RGS14	ENSMNEP00000042180	ENSMNEP00000033563	APC regulator of WNT signaling pathway.	Regulator of G protein signaling 14.	0.544