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| | E2F6 | E2F transcription factor 6. (255 aa) |
| | WEE2 | Wee1-like protein kinase. (568 aa) |
| | UBA52 | Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa) |
| | PRIM1 | DNA primase; Belongs to the eukaryotic-type primase small subunit family. (374 aa) |
| | ENSMNEP00000017045 | Hist_deacetyl domain-containing protein. (247 aa) |
| | PSMD11 | Proteasome 26S subunit, non-ATPase 11. (422 aa) |
| | SKP1 | S-phase kinase associated protein 1; Belongs to the SKP1 family. (163 aa) |
| | PSMD12 | Proteasome 26S subunit, non-ATPase 12. (456 aa) |
| | ENSMNEP00000045772 | DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (578 aa) |
| | CKS1B | Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa) |
| | SKP2 | S-phase kinase associated protein 2. (424 aa) |
| | ENSMNEP00000045253 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (234 aa) |
| | TFDP1 | Transcription factor. (410 aa) |
| | PSMB8 | Proteasome subunit beta. (276 aa) |
| | RPA3 | Replication protein A3. (121 aa) |
| | PSMC3 | AAA domain-containing protein; Belongs to the AAA ATPase family. (446 aa) |
| | CDK2 | Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. (346 aa) |
| | PSMB5 | Proteasome subunit beta. (263 aa) |
| | LIN52 | Lin-52 DREAM MuvB core complex component. (116 aa) |
| | ENSMNEP00000042738 | Uncharacterized protein. (394 aa) |
| | CDK1 | Cyclin dependent kinase 1; Belongs to the protein kinase superfamily. (297 aa) |
| | RBBP4 | RB binding protein 4, chromatin remodeling factor. (425 aa) |
| | ENSMNEP00000042381 | Uncharacterized protein. (312 aa) |
| | LOC105470589 | WRNPLPNID domain-containing protein. (954 aa) |
| | ENSMNEP00000042218 | Uncharacterized protein; Belongs to the SKP1 family. (171 aa) |
| | ENSMNEP00000042122 | Uncharacterized protein. (222 aa) |
| | PPP2CA | Serine/threonine-protein phosphatase. (309 aa) |
| | POLE3 | DNA polymerase epsilon 3, accessory subunit. (147 aa) |
| | ENSMNEP00000041258 | Prot_ATP_ID_OB domain-containing protein. (166 aa) |
| | PSMD10 | Proteasome 26S subunit, non-ATPase 10. (226 aa) |
| | ORC6 | Origin recognition complex subunit 6. (252 aa) |
| | MCM4 | DNA helicase; Belongs to the MCM family. (863 aa) |
| | PSMA2 | Proteasome subunit alpha type. (234 aa) |
| | GMNN | Geminin DNA replication inhibitor. (209 aa) |
| | PPP2CB | Serine/threonine-protein phosphatase. (309 aa) |
| | ENSMNEP00000039662 | Protein kinase domain-containing protein. (539 aa) |
| | PSMD4 | Proteasome 26S subunit, non-ATPase 4. (403 aa) |
| | PSMB2 | Proteasome subunit beta. (201 aa) |
| | ENSMNEP00000039425 | Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (86 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | ENSMNEP00000038934 | ATPase_AAA_core domain-containing protein; Belongs to the AAA ATPase family. (177 aa) |
| | MCM5 | DNA helicase; Belongs to the MCM family. (742 aa) |
| | RELCH | RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing. (1250 aa) |
| | ENSMNEP00000038452 | Uncharacterized protein. (396 aa) |
| | ORC5 | Origin recognition complex subunit 5. (435 aa) |
| | MCM7 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (719 aa) |
| | CCNH | Cyclin H; Belongs to the cyclin family. (325 aa) |
| | ENSMNEP00000036869 | Uncharacterized protein. (97 aa) |
| | PSMF1 | Proteasome inhibitor subunit 1. (271 aa) |
| | CDT1 | Chromatin licensing and DNA replication factor 1. (545 aa) |
| | ENSMNEP00000036101 | Uncharacterized protein. (167 aa) |
| | WEE1 | Wee1-like protein kinase. (646 aa) |
| | ENSMNEP00000035304 | Ubiquitin-like domain-containing protein. (134 aa) |
| | CCND1 | Cyclin D1; Belongs to the cyclin family. (295 aa) |
| | PSMD5 | Proteasome 26S subunit, non-ATPase 5. (493 aa) |
| | PSMD13 | Proteasome 26S subunit, non-ATPase 13. (339 aa) |
| | TFDP2 | Transcription factor. (447 aa) |
| | ENSMNEP00000032887 | Protein kinase domain-containing protein. (324 aa) |
| | PSMC1 | Proteasome 26S subunit, ATPase 1; Belongs to the AAA ATPase family. (440 aa) |
| | FNBP4 | Formin binding protein 4. (1017 aa) |
| | TYMS | Thymidylate synthetase. (313 aa) |
| | ENSMNEP00000031812 | Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (94 aa) |
| | LIN37 | Lin-37 DREAM MuvB core complex component. (246 aa) |
| | E2F5 | E2F transcription factor 5. (346 aa) |
| | LIN9 | Lin-9 DREAM MuvB core complex component. (558 aa) |
| | ENSMNEP00000030648 | EF-hand domain-containing protein. (559 aa) |
| | PSMB9 | Proteasome subunit beta. (219 aa) |
| | DBF4 | DBF4 zinc finger. (675 aa) |
| | CDC25A | Cell division cycle 25A. (524 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | PSMD14 | Proteasome 26S subunit, non-ATPase 14. (310 aa) |
| | PSMB3 | Proteasome subunit beta. (205 aa) |
| | ENSMNEP00000027884 | PROTEASOME_ALPHA_1 domain-containing protein. (45 aa) |
| | RPS27A | Ubiquitin-like domain-containing protein. (156 aa) |
| | RBL1 | RB transcriptional corepressor like 1. (1137 aa) |
| | TK1 | Thymidine kinase. (261 aa) |
| | HDAC1 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (483 aa) |
| | PSMA4 | Proteasome endopeptidase complex; Belongs to the peptidase T1A family. (307 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | ENSMNEP00000026028 | Uncharacterized protein. (77 aa) |
| | PSMD2 | 26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (912 aa) |
| | FBXO5 | F-box protein 5. (401 aa) |
| | PSMC5 | Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa) |
| | PPP2R1B | Protein phosphatase 2 scaffold subunit Abeta. (667 aa) |
| | ENSMNEP00000024470 | RPA_C domain-containing protein. (247 aa) |
| | MCM9 | Minichromosome maintenance 9 homologous recombination repair factor; Belongs to the MCM family. (1142 aa) |
| | MCM3 | DNA helicase; Belongs to the MCM family. (853 aa) |
| | CCNE2 | Cyclin E2; Belongs to the cyclin family. (404 aa) |
| | POLE | DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2263 aa) |
| | CUL1 | Cullin 1; Belongs to the cullin family. (776 aa) |
| | ENSMNEP00000023094 | Uncharacterized protein. (159 aa) |
| | PSMA3 | Proteasome subunit alpha type. (255 aa) |
| | ENSMNEP00000023008 | ANK_REP_REGION domain-containing protein. (159 aa) |
| | PSMB6 | Proteasome subunit beta. (285 aa) |
| | ENSMNEP00000022472 | AAA domain-containing protein; Belongs to the AAA ATPase family. (403 aa) |
| | PSMB7 | Proteasome subunit beta. (277 aa) |
| | MCM2 | DNA helicase; Belongs to the MCM family. (904 aa) |
| | ORC1 | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (858 aa) |
| | PSMB1 | Proteasome subunit beta. (241 aa) |
| | ENSMNEP00000002323 | WD_REPEATS_REGION domain-containing protein. (380 aa) |
| | PSMD7 | Proteasome 26S subunit, non-ATPase 7. (322 aa) |
| | PSMA6 | Proteasome subunit alpha type. (246 aa) |
| | LOC105475719 | Ubiquitin-like domain-containing protein. (127 aa) |
| | CCNA2 | Cyclin A2; Belongs to the cyclin family. (432 aa) |
| | ENSMNEP00000002753 | Ubiquitin-like domain-containing protein. (156 aa) |
| | CDC6 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (544 aa) |
| | ENSMNEP00000002894 | WD_REPEATS_REGION domain-containing protein. (419 aa) |
| | POLE4 | DNA polymerase epsilon 4, accessory subunit. (117 aa) |
| | PSMC2 | Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (468 aa) |
| | ENSMNEP00000004083 | Ubiquitin-like domain-containing protein. (127 aa) |
| | ENSMNEP00000004092 | Proteasome subunit alpha type. (231 aa) |
| | PSMD1 | 26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (851 aa) |
| | ENSMNEP00000004441 | 26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (788 aa) |
| | MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (454 aa) |
| | POLE2 | DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (527 aa) |
| | PPP2R3C | Protein phosphatase 2 regulatory subunit B''gamma. (453 aa) |
| | E2F4 | E2F transcription factor 4. (415 aa) |
| | ENSMNEP00000005796 | Ribosomal_S27 domain-containing protein. (137 aa) |
| | ENSMNEP00000005892 | Ubiquitin-like domain-containing protein. (156 aa) |
| | CDC7 | Protein kinase domain-containing protein. (574 aa) |
| | E2F1 | E2F transcription factor 1. (437 aa) |
| | CDK7 | Cyclin dependent kinase 7; Belongs to the protein kinase superfamily. (346 aa) |
| | CCNE1 | Cyclin E1; Belongs to the cyclin family. (407 aa) |
| | PSMA7 | Proteasome subunit alpha type. (248 aa) |
| | CDK3 | Cyclin dependent kinase 3; Belongs to the protein kinase superfamily. (333 aa) |
| | ENSMNEP00000007101 | Uncharacterized protein. (191 aa) |
| | PSME1 | Proteasome activator subunit 1. (249 aa) |
| | PSMD6 | Proteasome 26S subunit, non-ATPase 6. (442 aa) |
| | MCM10 | Minichromosome maintenance 10 replication initiation factor. (877 aa) |
| | ENSMNEP00000016650 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (458 aa) |
| | POLA1 | DNA polymerase. (1478 aa) |
| | RPA2 | Replication protein A2. (270 aa) |
| | CDK4 | Cyclin dependent kinase 4; Belongs to the protein kinase superfamily. (260 aa) |
| | PSMD3 | Proteasome 26S subunit, non-ATPase 3. (469 aa) |
| | ENSMNEP00000015951 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (443 aa) |
| | ENSMNEP00000015849 | Transcription factor. (392 aa) |
| | PCNA | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa) |
| | CDKN1B | Cyclin dependent kinase inhibitor 1B. (198 aa) |
| | ENSMNEP00000015014 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (596 aa) |
| | MNAT1 | CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (316 aa) |
| | PSMD8 | Proteasome 26S subunit, non-ATPase 8. (350 aa) |
| | MAX | MYC associated factor X. (160 aa) |
| | ORC4 | Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (436 aa) |
| | ENSMNEP00000014131 | Uncharacterized protein. (72 aa) |
| | PSME2 | Proteasome activator subunit 2. (254 aa) |
| | ORC3 | Origin recognition complex subunit 3. (712 aa) |
| | KIAA2012 | KIAA2012. (1180 aa) |
| | ORC2 | Origin recognition complex subunit 2. (577 aa) |
| | ENSMNEP00000012372 | WD_REPEATS_REGION domain-containing protein. (406 aa) |
| | PSMD9 | PDZ domain-containing protein. (223 aa) |
| | MCM6 | DNA helicase; Belongs to the MCM family. (785 aa) |
| | RB1 | RB transcriptional corepressor 1. (928 aa) |
| | CDC45 | Cell division cycle 45. (598 aa) |
| | ENSMNEP00000011567 | Uncharacterized protein; Belongs to the AAA ATPase family. (398 aa) |
| | PSMC4 | Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa) |
| | ENSMNEP00000010989 | Proteasome endopeptidase complex. (241 aa) |
| | ENSMNEP00000010901 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (547 aa) |
| | LIN54 | Lin-54 DREAM MuvB core complex component. (749 aa) |
| | PPP4R1 | Protein phosphatase 4 regulatory subunit 1. (933 aa) |
| | ENSMNEP00000010116 | CSN8_PSD8_EIF3K domain-containing protein. (243 aa) |
| | TM4SF19 | Uncharacterized protein. (209 aa) |
| | ENSMNEP00000008478 | Ubiquitin-like domain-containing protein. (120 aa) |
| | CCNA1 | Cyclin A1; Belongs to the cyclin family. (465 aa) |
| | CABLES1 | Cdk5 and Abl enzyme substrate 1. (628 aa) |
| | ENSMNEP00000008415 | Ubiquitin-like domain-containing protein. (83 aa) |
| | PPP4R4 | Protein phosphatase 4 regulatory subunit 4. (872 aa) |
| | PSMB4 | Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa) |
| | PSMB10 | Proteasome subunit beta. (273 aa) |
| | CKS2 | Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa) |
| | ENSMNEP00000000174 | AAA domain-containing protein; Belongs to the AAA ATPase family. (414 aa) |
| | CCNB1 | Cyclin B1; Belongs to the cyclin family. (433 aa) |
| | PSME3 | Proteasome activator subunit 3. (265 aa) |
| | MEIOB | Meiosis specific with OB-fold. (476 aa) |
| | PSMA1 | Proteasome subunit alpha type. (269 aa) |
| | ENSMNEP00000001266 | Uncharacterized protein. (234 aa) |
| | ENSMNEP00000001312 | Uncharacterized protein. (139 aa) |
| | ENSMNEP00000001356 | Uncharacterized protein. (139 aa) |
| | ENSMNEP00000001946 | Uncharacterized protein. (83 aa) |
| | ENSMNEP00000001974 | WD_REPEATS_REGION domain-containing protein. (415 aa) |
| | CDKN1A | Cyclin dependent kinase inhibitor 1A. (164 aa) |
| | PTK6 | Tyrosine-protein kinase. (397 aa) |
| | ENSMNEP00000007573 | MPN domain-containing protein. (149 aa) |
| | RRM2 | Ribonucleotide reductase regulatory subunit M2. (439 aa) |
| | PPP2R1A | Protein phosphatase 2 scaffold subunit Aalpha. (589 aa) |
| | PSMA5 | Proteasome subunit alpha type. (241 aa) |
| | PPP2R3A | Protein phosphatase 2 regulatory subunit B''alpha. (1127 aa) |
| | MCM8 | MCM domain-containing protein; Belongs to the MCM family. (863 aa) |
| | ENSMNEP00000019698 | WD_REPEATS_REGION domain-containing protein. (381 aa) |
| | RBL2 | RB transcriptional corepressor like 2. (1141 aa) |
| | ENSMNEP00000019162 | AAA domain-containing protein; Belongs to the AAA ATPase family. (393 aa) |
