STRINGSTRING
CLP1 CLP1 ENSMNEP00000003449 ENSMNEP00000003449 SYMPK SYMPK CSTF3 CSTF3 LOC105481505 LOC105481505 FIP1L1 FIP1L1 SRSF6 SRSF6 SRSF1 SRSF1 CSTF1 CSTF1 THOC6 THOC6 SLU7 SLU7 MAGOHB MAGOHB CDC40 CDC40 SRSF11 SRSF11 CPSF7 CPSF7 LOC105472065 LOC105472065 C12orf50 C12orf50 U2AF1 U2AF1 ENSMNEP00000012850 ENSMNEP00000012850 SREK1 SREK1 SRSF5 SRSF5 ENSMNEP00000013289 ENSMNEP00000013289 ENSMNEP00000014114 ENSMNEP00000014114 ENSMNEP00000014519 ENSMNEP00000014519 SRSF2 SRSF2 CPSF2 CPSF2 MAGOH MAGOH CPSF4 CPSF4 RNPS1 RNPS1 CHTOP CHTOP THOC2 THOC2 SRSF4 SRSF4 THOC7 THOC7 ENSMNEP00000024434 ENSMNEP00000024434 CPSF6 CPSF6 SRSF7 SRSF7 POLDIP3 POLDIP3 U2AF1L4 U2AF1L4 ENSMNEP00000029572 ENSMNEP00000029572 SRSF3 SRSF3 ENSMNEP00000029945 ENSMNEP00000029945 ENSMNEP00000029986 ENSMNEP00000029986 FYTTD1 FYTTD1 WDR33 WDR33 NUDT21 NUDT21 PCF11 PCF11 EIF4A3 EIF4A3 CPSF3 CPSF3 SRRM1 SRRM1 UPF3B UPF3B THOC1 THOC1 THOC5 THOC5 RBM8A RBM8A NCBP2 NCBP2 ENSMNEP00000035495 ENSMNEP00000035495 DDX39B DDX39B ENSMNEP00000036886 ENSMNEP00000036886 ENSMNEP00000037375 ENSMNEP00000037375 CSTF2 CSTF2 U2AF2 U2AF2 NCBP1 NCBP1 THOC3 THOC3 CPSF1 CPSF1 ALYREF ALYREF LUZP4 LUZP4 PAPOLA PAPOLA SRSF9 SRSF9 DDX39A DDX39A SARNP SARNP ENSMNEP00000044248 ENSMNEP00000044248 BCL2L2-PABPN1 BCL2L2-PABPN1 DHX38 DHX38 CPSF4L CPSF4L
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CLP1Polyribonucleotide 5'-hydroxyl-kinase Clp1; Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. dsRNA is phosphorylated more efficiently than dsDNA, and the RNA component of a DNA:RNA hybrid is phosphorylated more efficiently than the DNA component. Appears to have roles in both tRNA splicing and mRNA 3'-end formation. Component of the tRNA splicing endonuclease complex. Phosphorylates the 5'-terminus of the tRNA 3'-exon during tRNA splicing; thi [...] (425 aa)
ENSMNEP00000003449Uncharacterized protein. (253 aa)
SYMPKSymplekin. (1304 aa)
CSTF3Cleavage stimulation factor subunit 3. (717 aa)
LOC105481505RRM domain-containing protein. (285 aa)
FIP1L1Fip1 domain-containing protein. (603 aa)
SRSF6Serine and arginine rich splicing factor 6. (343 aa)
SRSF1Uncharacterized protein. (253 aa)
CSTF1Cleavage stimulation factor subunit 1. (431 aa)
THOC6THO complex 6. (341 aa)
SLU7SLU7 homolog, splicing factor. (586 aa)
MAGOHBMago homolog B, exon junction complex subunit. (148 aa)
CDC40Cell division cycle 40. (579 aa)
SRSF11Serine and arginine rich splicing factor 11. (483 aa)
CPSF7Cleavage and polyadenylation specific factor 7. (478 aa)
LOC105472065Uncharacterized protein. (229 aa)
C12orf50Chromosome 12 open reading frame 50. (414 aa)
U2AF1Uncharacterized protein. (246 aa)
ENSMNEP00000012850SAP domain-containing protein. (190 aa)
SREK1Splicing regulatory glutamic acid and lysine rich protein 1. (626 aa)
SRSF5Serine and arginine rich splicing factor 5. (272 aa)
ENSMNEP00000013289Uncharacterized protein. (136 aa)
ENSMNEP00000014114Uncharacterized protein. (799 aa)
ENSMNEP00000014519RRM domain-containing protein. (295 aa)
SRSF2Serine and arginine rich splicing factor 2. (221 aa)
CPSF2Cleavage and polyadenylation specificity factor subunit 2. (782 aa)
MAGOHMago homolog, exon junction complex subunit. (146 aa)
CPSF4Cleavage and polyadenylation specific factor 4. (269 aa)
RNPS1RRM domain-containing protein. (295 aa)
CHTOPChromatin target of PRMT1. (277 aa)
THOC2THO complex 2. (1593 aa)
SRSF4Serine and arginine rich splicing factor 4. (494 aa)
THOC7THO complex 7. (204 aa)
ENSMNEP00000024434RRM domain-containing protein. (253 aa)
CPSF6Cleavage and polyadenylation specific factor 6. (589 aa)
SRSF7Serine and arginine rich splicing factor 7. (238 aa)
POLDIP3DNA polymerase delta interacting protein 3. (436 aa)
U2AF1L4Uncharacterized protein. (211 aa)
ENSMNEP00000029572annotation not available (343 aa)
SRSF3Serine and arginine rich splicing factor 3. (164 aa)
ENSMNEP00000029945Uncharacterized protein. (139 aa)
ENSMNEP00000029986Uncharacterized protein; Belongs to the DEAD box helicase family. (387 aa)
FYTTD1Forty-two-three domain containing 1. (318 aa)
WDR33WD repeat domain 33. (1336 aa)
NUDT21Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...] (227 aa)
PCF11PCF11 cleavage and polyadenylation factor subunit. (1686 aa)
EIF4A3Uncharacterized protein; Belongs to the DEAD box helicase family. (428 aa)
CPSF3Cleavage and polyadenylation specific factor 3. (625 aa)
SRRM1Serine and arginine repetitive matrix 1. (917 aa)
UPF3BUPF3B regulator of nonsense mediated mRNA decay. (483 aa)
THOC1THO complex 1. (660 aa)
THOC5THO complex 5. (677 aa)
RBM8ARNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. (174 aa)
NCBP2Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (156 aa)
ENSMNEP00000035495Smg4_UPF3 domain-containing protein. (194 aa)
DDX39BDExD-box helicase 39B. (428 aa)
ENSMNEP00000036886SAP domain-containing protein. (213 aa)
ENSMNEP00000037375SAP domain-containing protein. (173 aa)
CSTF2Cleavage stimulation factor subunit 2. (597 aa)
U2AF2U2 snRNP auxiliary factor large subunit; Necessary for the splicing of pre-mRNA. Belongs to the splicing factor SR family. (471 aa)
NCBP1Nuclear cap binding protein subunit 1. (790 aa)
THOC3THO complex 3. (351 aa)
CPSF1Cleavage and polyadenylation specific factor 1. (1394 aa)
ALYREFAly/REF export factor. (290 aa)
LUZP4Leucine zipper protein 4. (306 aa)
PAPOLAPoly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's. (745 aa)
SRSF9Serine and arginine rich splicing factor 9. (221 aa)
DDX39ADExD-box helicase 39A. (488 aa)
SARNPSAP domain containing ribonucleoprotein. (210 aa)
ENSMNEP00000044248Uncharacterized protein. (138 aa)
BCL2L2-PABPN1BCL2L2-PABPN1 readthrough. (333 aa)
DHX38DEAH-box helicase 38. (1229 aa)
CPSF4LCleavage and polyadenylation specific factor 4 like. (179 aa)
Your Current Organism:
Macaca nemestrina
NCBI taxonomy Id: 9545
Other names: M. nemestrina, pig-tailed macaque, pigtail macaque, pigtail monkey
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.