STRINGSTRING
STN1 STN1 DARS1 DARS1 DARS2 DARS2 NARS2 NARS2 G3QDJ6_GORGO G3QDJ6_GORGO NABP2 NABP2 KARS1 KARS1 NARS1 NARS1 RPA1 RPA1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
STN1CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication. (368 aa)
DARS1Aspartyl-tRNA synthetase. (501 aa)
DARS2Aspartyl-tRNA synthetase 2, mitochondrial. (645 aa)
NARS2Asparaginyl-tRNA synthetase 2, mitochondrial. (477 aa)
G3QDJ6_GORGOOB domain-containing protein. (169 aa)
NABP2Nucleic acid binding protein 2. (211 aa)
KARS1Lysine--tRNA ligase. (629 aa)
NARS1Asparaginyl-tRNA synthetase. (548 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (585 aa)
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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