STRINGSTRING
ZDHHC6 ZDHHC6 GRAP2 GRAP2 ENSPPAP00000008140 ENSPPAP00000008140 BAIAP2 BAIAP2 MYO15A MYO15A SORBS1 SORBS1 SRMS SRMS ARHGEF37 ARHGEF37 CACNB2 CACNB2 BCAR1 BCAR1 BAIAP2L2 BAIAP2L2 DLG1 DLG1 CASKIN2 CASKIN2 NCK1 NCK1 NEDD9 NEDD9 ARHGAP12 ARHGAP12 SH3GLB2 SH3GLB2 SKAP1 SKAP1 DOCK3 DOCK3 ARHGAP4 ARHGAP4 PLCG2 PLCG2 DLG3 DLG3 FYB FYB OBSCN OBSCN EVPL EVPL GRAPL GRAPL OSTF1 OSTF1 STAC STAC SHANK2 SHANK2 SH3PXD2A SH3PXD2A GRAP GRAP CASK CASK NEBL NEBL DLG2 DLG2 MPP1 MPP1 SRGAP2 SRGAP2 PACSIN3 PACSIN3 TJP1 TJP1 SRC SRC TJP3 TJP3 ITSN1 ITSN1 PRAM1 PRAM1 ARHGEF26 ARHGEF26 DOCK1 DOCK1 DOCK5 DOCK5 CD2AP CD2AP ENSPPAP00000036655 ENSPPAP00000036655 DOCK2 DOCK2 SPTA1 SPTA1 FGR FGR ARHGAP33 ARHGAP33 KALRN KALRN MAPK8IP2 MAPK8IP2 SASH1 SASH1 FNBP1L FNBP1L CRK CRK RUSC1 RUSC1 TEC TEC MACC1 MACC1 LYN LYN SKAP2 SKAP2 TNK1 TNK1 ABI2 ABI2 STAC2 STAC2 PPL PPL EPS8L2 EPS8L2 MIA3 MIA3 TSPOAP1 TSPOAP1 DOCK4 DOCK4 CTTN CTTN DLG5 DLG5 SLA SLA PIK3R1 PIK3R1 ASAP1 ASAP1 PLEC PLEC FCHSD2 FCHSD2 ARHGAP27 ARHGAP27 TP53BP2 TP53BP2 MAP3K10 MAP3K10 SH3D19 SH3D19 NCF1 NCF1 DBNL DBNL PLCG1 PLCG1 MYO1F MYO1F STAC3 STAC3 AHI1 AHI1 DNMBP DNMBP RASA1 RASA1 DSP DSP ITK ITK SGSM3 SGSM3 MPP3 MPP3 UBASH3B UBASH3B NPHP1 NPHP1 LCK LCK LOC100988721 LOC100988721 SORBS3 SORBS3 UBASH3A UBASH3A EPS8L1 EPS8L1 ARHGAP42 ARHGAP42 SRGAP1 SRGAP1 MIA MIA ARHGAP32 ARHGAP32 TRIO TRIO AMPH AMPH PACSIN1 PACSIN1 SNX33 SNX33 SH3RF2 SH3RF2 CASS4 CASS4 ARHGEF19 ARHGEF19 MPP2 MPP2 SH3RF1 SH3RF1 TRIP10 TRIP10 NOXO1 NOXO1 MYO7B MYO7B ENSPPAP00000041190 ENSPPAP00000041190 PPP1R13B PPP1R13B ARHGAP9 ARHGAP9 SH3BP4 SH3BP4 ABL2 ABL2 GAS7 GAS7 BIN1 BIN1 SORBS2 SORBS2 MAP3K9 MAP3K9 CASKIN1 CASKIN1 PTK6 PTK6 GRB2 GRB2 SH3YL1 SH3YL1 FNBP1 FNBP1 BLK BLK CACNB3 CACNB3 MAPK8IP1 MAPK8IP1 SH3RF3 SH3RF3 ASAP2 ASAP2 MATK MATK PSTPIP1 PSTPIP1 LASP1 LASP1 SH3GL3 SH3GL3 MIA2 MIA2 ARHGAP10 ARHGAP10 PEX13 PEX13 PIK3R2 PIK3R2 CACNB4 CACNB4 CSK CSK SH3D21 SH3D21 SH3GL1 SH3GL1 SH3PXD2B SH3PXD2B SNX9 SNX9 ARHGEF6 ARHGEF6 MAP3K11 MAP3K11 SH3TC1 SH3TC1 MACF1 MACF1 MPP7 MPP7 SH3GL2 SH3GL2 STAM STAM RUSC2 RUSC2 HCLS1 HCLS1 PRMT2 PRMT2 MYO7A MYO7A ENSPPAP00000025160 ENSPPAP00000025160 MPP4 MPP4 FYN FYN ABL1 ABL1 SASH3 SASH3 MPP6 MPP6 VAV1 VAV1 SLA2 SLA2 MPP5 MPP5 SPTAN1 SPTAN1 PACSIN2 PACSIN2 SAMSN1 SAMSN1 ENSPPAP00000027754 ENSPPAP00000027754 MCF2L MCF2L NOXA1 NOXA1 TXK TXK SH3GLB1 SH3GLB1 SPATA13 SPATA13 VAV2 VAV2 STAM2 STAM2 FRK FRK RIMBP2 RIMBP2 NCK2 NCK2 DLG4 DLG4 HCK HCK NGEF NGEF SH3KBP1 SH3KBP1 TJP2 TJP2 SRGAP3 SRGAP3 NCF2 NCF2 SHANK1 SHANK1 BTK BTK ABI1 ABI1 YES1 YES1 OTOR OTOR EFS EFS EPS8 EPS8 ITSN2 ITSN2 CRKL CRKL SH3TC2 SH3TC2 ARHGEF16 ARHGEF16 ARHGEF9 ARHGEF9 DST DST ARHGAP26 ARHGAP26 ARHGEF7 ARHGEF7 NCF4 NCF4 MYO15B MYO15B VAV3 VAV3 ABI3 ABI3 ARHGEF5 ARHGEF5 FUT8 FUT8
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ZDHHC6Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (412 aa)
GRAP2GRB2 related adaptor protein 2. (330 aa)
ENSPPAP00000008140Uncharacterized protein. (547 aa)
BAIAP2BAI1 associated protein 2. (549 aa)
MYO15AUncharacterized protein. (797 aa)
SORBS1Sorbin and SH3 domain containing 1. (1292 aa)
SRMSTyrosine-protein kinase. (491 aa)
ARHGEF37Rho guanine nucleotide exchange factor 37. (686 aa)
CACNB2Calcium voltage-gated channel auxiliary subunit beta 2. (660 aa)
BCAR1BCAR1 scaffold protein, Cas family member. (916 aa)
BAIAP2L2BAI1 associated protein 2 like 2. (517 aa)
DLG1Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (926 aa)
CASKIN2CASK interacting protein 2. (1174 aa)
NCK1Cytoplasmic protein. (377 aa)
NEDD9Neural precursor cell expressed, developmentally down-regulated 9. (839 aa)
ARHGAP12Rho GTPase activating protein 12. (846 aa)
SH3GLB2SH3 domain containing GRB2 like, endophilin B2. (383 aa)
SKAP1Src kinase associated phosphoprotein 1. (359 aa)
DOCK3Dedicator of cytokinesis 3; Belongs to the DOCK family. (2017 aa)
ARHGAP4Rho GTPase activating protein 4. (986 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
DLG3Discs large MAGUK scaffold protein 3; Belongs to the MAGUK family. (748 aa)
FYBSH3 domain-containing protein. (635 aa)
OBSCNObscurin, cytoskeletal calmodulin and titin-interacting RhoGEF. (8732 aa)
EVPLEnvoplakin. (1968 aa)
GRAPLGRB2 related adaptor protein like. (100 aa)
OSTF1Osteoclast stimulating factor 1. (202 aa)
STACSH3 and cysteine rich domain. (402 aa)
SHANK2Uncharacterized protein. (1849 aa)
SH3PXD2ASH3 and PX domains 2A. (1113 aa)
GRAPUncharacterized protein. (158 aa)
CASKCalcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family. (926 aa)
NEBLNebulette. (1014 aa)
DLG2Discs large MAGUK scaffold protein 2. (939 aa)
MPP1Membrane palmitoylated protein 1; Belongs to the MAGUK family. (466 aa)
SRGAP2SLIT-ROBO Rho GTPase activating protein 2. (1071 aa)
PACSIN3Protein kinase C and casein kinase substrate in neurons 3. (424 aa)
TJP1Tight junction protein 1; Belongs to the MAGUK family. (1772 aa)
SRCTyrosine-protein kinase. (458 aa)
TJP3Tight junction protein 3; Belongs to the MAGUK family. (928 aa)
ITSN1Intersectin 1. (1720 aa)
PRAM1SH3 domain-containing protein. (830 aa)
ARHGEF26Rho guanine nucleotide exchange factor 26. (871 aa)
DOCK1Dedicator of cytokinesis 1; Belongs to the DOCK family. (1870 aa)
DOCK5Dedicator of cytokinesis 5; Belongs to the DOCK family. (1870 aa)
CD2APCD2 associated protein. (650 aa)
ENSPPAP00000036655Uncharacterized protein. (389 aa)
DOCK2Dedicator of cytokinesis 2; Belongs to the DOCK family. (1815 aa)
SPTA1Spectrin alpha, erythrocytic 1. (2338 aa)
FGRTyrosine-protein kinase. (529 aa)
ARHGAP33Rho GTPase activating protein 33. (1142 aa)
KALRNUncharacterized protein. (2958 aa)
MAPK8IP2Mitogen-activated protein kinase 8 interacting protein 2. (692 aa)
SASH1SAM and SH3 domain containing 1. (1251 aa)
FNBP1LFormin binding protein 1 like. (611 aa)
CRKCRK proto-oncogene, adaptor protein. (304 aa)
RUSC1RUN and SH3 domain containing 1. (902 aa)
TECTyrosine-protein kinase. (631 aa)
MACC1MET transcriptional regulator MACC1. (852 aa)
LYNTyrosine-protein kinase. (526 aa)
SKAP2Src kinase associated phosphoprotein 2. (359 aa)
TNK1Tyrosine kinase non receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (666 aa)
ABI2Abl interactor 2. (513 aa)
STAC2SH3 and cysteine rich domain 2. (411 aa)
PPLPeriplakin. (1747 aa)
EPS8L2EPS8 like 2. (716 aa)
MIA3MIA SH3 domain ER export factor 3. (1871 aa)
TSPOAP1TSPO associated protein 1. (1867 aa)
DOCK4Dedicator of cytokinesis 4; Belongs to the DOCK family. (2011 aa)
CTTNSH3 domain-containing protein. (550 aa)
DLG5Discs large MAGUK scaffold protein 5; Belongs to the MAGUK family. (1809 aa)
SLASrc like adaptor. (293 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (736 aa)
ASAP1ArfGAP with SH3 domain, ankyrin repeat and PH domain 1. (1129 aa)
PLECPlectin. (4523 aa)
FCHSD2Uncharacterized protein. (591 aa)
ARHGAP27Rho GTPase activating protein 27. (740 aa)
TP53BP2Tumor protein p53 binding protein 2. (1137 aa)
MAP3K10Mitogen-activated protein kinase kinase kinase 10. (793 aa)
SH3D19SH3 domain containing 19. (790 aa)
NCF1Neutrophil cytosolic factor 1. (390 aa)
DBNLDrebrin like. (489 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1248 aa)
MYO1FMyosin IF; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (988 aa)
STAC3SH3 and cysteine rich domain 3. (364 aa)
AHI1Abelson helper integration site 1. (1240 aa)
DNMBPDynamin binding protein. (1571 aa)
RASA1RAS p21 protein activator 1. (1047 aa)
DSPDesmoplakin. (2871 aa)
ITKTyrosine-protein kinase. (620 aa)
SGSM3Small G protein signaling modulator 3. (757 aa)
MPP3Membrane palmitoylated protein 3; Belongs to the MAGUK family. (597 aa)
UBASH3BUbiquitin associated and SH3 domain containing B. (649 aa)
NPHP1Nephrocystin 1. (729 aa)
LCKTyrosine-protein kinase. (524 aa)
LOC100988721Uncharacterized protein. (1815 aa)
SORBS3Sorbin and SH3 domain containing 3. (671 aa)
UBASH3AUbiquitin associated and SH3 domain containing A. (661 aa)
EPS8L1EPS8 like 1. (659 aa)
ARHGAP42Rho GTPase activating protein 42. (874 aa)
SRGAP1SLIT-ROBO Rho GTPase activating protein 1. (1085 aa)
MIAMIA SH3 domain containing. (131 aa)
ARHGAP32Rho GTPase activating protein 32. (2075 aa)
TRIOTrio Rho guanine nucleotide exchange factor. (2877 aa)
AMPHAmphiphysin. (695 aa)
PACSIN1Protein kinase C and casein kinase substrate in neurons 1. (444 aa)
SNX33Sorting nexin. (574 aa)
SH3RF2SH3 domain containing ring finger 2. (729 aa)
CASS4Cas scaffold protein family member 4. (812 aa)
ARHGEF19Rho guanine nucleotide exchange factor 19. (804 aa)
MPP2Membrane palmitoylated protein 2; Belongs to the MAGUK family. (597 aa)
SH3RF1SH3 domain containing ring finger 1. (888 aa)
TRIP10Thyroid hormone receptor interactor 10. (601 aa)
NOXO1Uncharacterized protein. (482 aa)
MYO7BMyosin VIIB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2116 aa)
ENSPPAP00000041190SH3 domain-containing protein. (6597 aa)
PPP1R13BProtein phosphatase 1 regulatory subunit 13B. (1090 aa)
ARHGAP9Rho GTPase activating protein 9. (821 aa)
SH3BP4SH3 domain binding protein 4. (963 aa)
ABL2Tyrosine-protein kinase. (1131 aa)
GAS7Growth arrest specific 7. (476 aa)
BIN1Bridging integrator 1. (585 aa)
SORBS2Sorbin and SH3 domain containing 2. (1202 aa)
MAP3K9Mitogen-activated protein kinase kinase kinase 9. (1117 aa)
CASKIN1Uncharacterized protein. (848 aa)
PTK6Tyrosine-protein kinase. (451 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
SH3YL1SH3 and SYLF domain containing 1. (383 aa)
FNBP1Formin binding protein 1. (621 aa)
BLKTyrosine-protein kinase. (505 aa)
CACNB3Calcium voltage-gated channel auxiliary subunit beta 3. (488 aa)
MAPK8IP1Mitogen-activated protein kinase 8 interacting protein 1. (713 aa)
SH3RF3SH3 domain containing ring finger 3. (839 aa)
ASAP2ArfGAP with SH3 domain, ankyrin repeat and PH domain 2. (988 aa)
MATKTyrosine-protein kinase. (514 aa)
PSTPIP1Proline-serine-threonine phosphatase interacting protein 1. (404 aa)
LASP1LIM and SH3 protein 1. (261 aa)
SH3GL3SH3 domain containing GRB2 like 3, endophilin A3. (355 aa)
MIA2MIA SH3 domain ER export factor 2. (1412 aa)
ARHGAP10Rho GTPase activating protein 10. (786 aa)
PEX13Peroxisomal biogenesis factor 13. (403 aa)
PIK3R2Uncharacterized protein. (663 aa)
CACNB4Calcium voltage-gated channel auxiliary subunit beta 4. (520 aa)
CSKTyrosine-protein kinase. (450 aa)
SH3D21SH3 domain containing 21. (754 aa)
SH3GL1SH3 domain containing GRB2 like 1, endophilin A2. (368 aa)
SH3PXD2BSH3 and PX domains 2B. (902 aa)
SNX9Sorting nexin. (596 aa)
ARHGEF6Rac/Cdc42 guanine nucleotide exchange factor 6. (783 aa)
MAP3K11Mitogen-activated protein kinase kinase kinase 11. (833 aa)
SH3TC1SH3 domain and tetratricopeptide repeats 1. (1336 aa)
MACF1Uncharacterized protein. (7567 aa)
MPP7Membrane palmitoylated protein 7; Belongs to the MAGUK family. (576 aa)
SH3GL2SH3 domain containing GRB2 like 2, endophilin A1. (337 aa)
STAMSignal transducing adaptor molecule. (540 aa)
RUSC2RUN and SH3 domain containing 2. (1513 aa)
HCLS1Hematopoietic cell-specific Lyn substrate 1. (484 aa)
PRMT2Protein arginine methyltransferase 2; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (433 aa)
MYO7AMyosin VIIA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2222 aa)
ENSPPAP00000025160Tyrosine-protein kinase. (483 aa)
MPP4Membrane palmitoylated protein 4; Belongs to the MAGUK family. (605 aa)
FYNTyrosine-protein kinase. (537 aa)
ABL1Tyrosine-protein kinase. (1149 aa)
SASH3SAM and SH3 domain containing 3. (380 aa)
MPP6Membrane palmitoylated protein 6; Belongs to the MAGUK family. (582 aa)
VAV1Vav guanine nucleotide exchange factor 1. (828 aa)
SLA2Src like adaptor 2. (261 aa)
MPP5Membrane palmitoylated protein 5; Belongs to the MAGUK family. (675 aa)
SPTAN1Spectrin alpha, non-erythrocytic 1. (2498 aa)
PACSIN2Protein kinase C and casein kinase substrate in neurons 2. (486 aa)
SAMSN1SAM domain, SH3 domain and nuclear localization signals 1. (441 aa)
ENSPPAP00000027754Uncharacterized protein. (458 aa)
MCF2LMCF.2 cell line derived transforming sequence like. (1137 aa)
NOXA1NADPH oxidase activator 1. (483 aa)
TXKTyrosine-protein kinase. (527 aa)
SH3GLB1SH3 domain containing GRB2 like, endophilin B1. (394 aa)
SPATA13Uncharacterized protein. (1279 aa)
VAV2Vav guanine nucleotide exchange factor 2. (810 aa)
STAM2Signal transducing adaptor molecule 2. (525 aa)
FRKTyrosine-protein kinase. (505 aa)
RIMBP2RIMS binding protein 2. (1052 aa)
NCK2Cytoplasmic protein. (380 aa)
DLG4Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family. (767 aa)
HCKTyrosine-protein kinase. (526 aa)
NGEFNeuronal guanine nucleotide exchange factor. (710 aa)
SH3KBP1SH3 domain containing kinase binding protein 1. (664 aa)
TJP2Uncharacterized protein; Belongs to the MAGUK family. (1245 aa)
SRGAP3SLIT-ROBO Rho GTPase activating protein 3. (1089 aa)
NCF2Neutrophil cytosolic factor 2. (526 aa)
SHANK1SH3 and multiple ankyrin repeat domains 1. (2007 aa)
BTKTyrosine-protein kinase. (693 aa)
ABI1Abl interactor 1. (508 aa)
YES1Tyrosine-protein kinase. (548 aa)
OTOROtoraplin. (128 aa)
EFSEmbryonal Fyn-associated substrate. (549 aa)
EPS8Epidermal growth factor receptor pathway substrate 8. (822 aa)
ITSN2Intersectin 2. (1693 aa)
CRKLCRK like proto-oncogene, adaptor protein. (303 aa)
SH3TC2SH3 domain and tetratricopeptide repeats 2. (1259 aa)
ARHGEF16Rho guanine nucleotide exchange factor 16. (701 aa)
ARHGEF9Cdc42 guanine nucleotide exchange factor 9. (587 aa)
DSTUncharacterized protein. (7445 aa)
ARHGAP26Rho GTPase activating protein 26. (774 aa)
ARHGEF7Rho guanine nucleotide exchange factor 7. (780 aa)
NCF4Uncharacterized protein. (368 aa)
MYO15BMyosin XVB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (3012 aa)
VAV3Vav guanine nucleotide exchange factor 3. (917 aa)
ABI3ABI family member 3. (366 aa)
ARHGEF5Rho guanine nucleotide exchange factor 5. (1597 aa)
FUT8Alpha-(1,6)-fucosyltransferase; Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans. Belongs to the glycosyltransferase 23 family. (575 aa)
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
Server load: low (22%) [HD]