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HMGCL HMGCL MECR MECR HPDL HPDL ECHDC2 ECHDC2 CPT2 CPT2 HMGCS2 HMGCS2 GLYAT GLYAT AASDHPPT AASDHPPT ACAT1 ACAT1 ACAD8 ACAD8 ACADS ACADS AACS AACS CRYL1 CRYL1 PCCA PCCA ETFA ETFA ACSBG1 ACSBG1 ECI1 ECI1 ACSM5 ACSM5 ACSM2A ACSM2A ACSM3 ACSM3 MLYCD MLYCD GLOD4 GLOD4 FASN FASN ACAA2 ACAA2 GCDH GCDH HADHA HADHA HADHB HADHB ACADL ACADL ACSL3 ACSL3 HLCS HLCS DIP2A DIP2A MCAT MCAT ACAA1 ACAA1 ACOX2 ACOX2 ACAD11 ACAD11 MCCC1 MCCC1 EHHADH EHHADH BDH2 BDH2 ACSL1 ACSL1 MCCC2 MCCC2 ECI2 ECI2 PPT2 PPT2 HSD17B8 HSD17B8 ECHDC1 ECHDC1 ACAT2 ACAT2 SBSPON SBSPON ACSM6 ACSM6 ACSL4 ACSL4 ECH1 ECH1 ECHS1 ECHS1 ACSL5 ACSL5 CPT1B CPT1B CBR4 CBR4 CPT1C CPT1C CARTPT CARTPT PECR PECR SLC27A1 SLC27A1 ACADM ACADM ACSM2A-2 ACSM2A-2 ETFDH ETFDH L1TD1 L1TD1 HSDL2 HSDL2 LOC745547 LOC745547 HTD2 HTD2 ENSPTRP00000060782 ENSPTRP00000060782 ENSPTRP00000061578 ENSPTRP00000061578 HADH HADH LOC100612090 LOC100612090 ACOX3 ACOX3 HSD17B4 HSD17B4 DHTKD1 DHTKD1 ENSPTRP00000066028 ENSPTRP00000066028 PCCB PCCB ACADVL ACADVL ACOX1 ACOX1 AASS AASS ETFB ETFB ACOXL ACOXL CPT1A CPT1A IVD IVD ACACA ACACA BDH1 BDH1 ACSF3 ACSF3 ACADSB ACADSB ENSPTRP00000077599 ENSPTRP00000077599 ACACB ACACB SCP2D1 SCP2D1 CK820_G0051181 CK820_G0051181 AASDH AASDH CK820_G0015962 CK820_G0015962 LOC744070 LOC744070 CK820_G0041188 CK820_G0041188 SLC27A4 SLC27A4 OXCT1 OXCT1 BTD BTD OXSM OXSM HSD17B14 HSD17B14 SMIM24 SMIM24 OLAH OLAH ENSPTRP00000087701 ENSPTRP00000087701 ENSPTRP00000089862 ENSPTRP00000089862 ACSF2 ACSF2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HMGCL3-hydroxymethyl-3-methylglutaryl-CoA lyase. (325 aa)
MECRMitochondrial trans-2-enoyl-CoA reductase. (297 aa)
HPDL4-hydroxyphenylpyruvate dioxygenase. (371 aa)
ECHDC2Enoyl-CoA hydratase domain containing 2; Belongs to the enoyl-CoA hydratase/isomerase family. (292 aa)
CPT2Carnitine palmitoyltransferase 2; Belongs to the carnitine/choline acetyltransferase family. (658 aa)
HMGCS23-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (508 aa)
GLYATGlycine-N-acyltransferase. (296 aa)
AASDHPPTAminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase. (309 aa)
ACAT1Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. (427 aa)
ACAD8Acyl-CoA dehydrogenase family, member 8. (415 aa)
ACADSAcyl-CoA dehydrogenase, C-2 to C-3 short chain. (412 aa)
AACSAcetoacetyl-CoA synthetase. (672 aa)
CRYL1Crystallin, lambda 1. (319 aa)
PCCAPropionyl CoA carboxylase, alpha polypeptide. (728 aa)
ETFAElectron-transfer-flavoprotein, alpha polypeptide. (333 aa)
ACSBG1Acyl-CoA synthetase bubblegum family member 1. (724 aa)
ECI1Enoyl-CoA delta isomerase 1; Belongs to the enoyl-CoA hydratase/isomerase family. (302 aa)
ACSM5ACSM5 isoform 2. (560 aa)
ACSM2AAcyl-CoA synthetase medium chain family member 2B. (577 aa)
ACSM3Acyl-CoA synthetase medium chain family member 3. (586 aa)
MLYCDMalonyl-CoA decarboxylase, mitochondrial. (493 aa)
GLOD4GLOD4 isoform 3. (476 aa)
FASNFatty acid synthase. (2511 aa)
ACAA2Acetyl-CoA acyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. (397 aa)
GCDHGlutaryl-CoA dehydrogenase. (438 aa)
HADHAHydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha; Belongs to the enoyl-CoA hydratase/isomerase family. (763 aa)
HADHBTrifunctional enzyme subunit beta, mitochondrial; Mitochondrial trifunctional enzyme catalyzes the last three of the four reactions of the mitochondrial beta-oxidation pathway. The mitochondrial beta-oxidation pathway is the major energy-producing process in tissues and is performed through four consecutive reactions breaking down fatty acids into acetyl-CoA. Among the enzymes involved in this pathway, the trifunctional enzyme exhibits specificity for long-chain fatty acids. Mitochondrial trifunctional enzyme is a heterotetrameric complex composed of two proteins, the trifunctional enz [...] (475 aa)
ACADLAcyl-CoA dehydrogenase long chain. (430 aa)
ACSL3Acyl-CoA synthetase long-chain family member 3. (720 aa)
HLCSHolocarboxylase synthetase (Biotin-(Proprionyl-Coenzyme A-carboxylase (ATP-hydrolysing)) ligase). (726 aa)
DIP2ADIP2 disco-interacting protein 2 homolog A. (1571 aa)
MCATMalonyl CoA:ACP acyltransferase (Mitochondrial). (390 aa)
ACAA1Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. (424 aa)
ACOX2Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (681 aa)
ACAD11Acyl-CoA dehydrogenase family member 11 isoform X1. (780 aa)
MCCC1Methylcrotonoyl-CoA carboxylase 1 (Alpha). (725 aa)
EHHADHEnoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase; Belongs to the enoyl-CoA hydratase/isomerase family. (723 aa)
BDH23-hydroxybutyrate dehydrogenase, type 2. (245 aa)
ACSL1ACSL1 isoform 9. (698 aa)
MCCC2Methylcrotonoyl-CoA carboxylase 2 (Beta). (563 aa)
ECI2Enoyl-CoA delta isomerase 2. (394 aa)
PPT2PPT2-EGFL8 isoform 1. (308 aa)
HSD17B8Hydroxysteroid (17-beta) dehydrogenase 8. (261 aa)
ECHDC1Ethylmalonyl-CoA decarboxylase 1; Belongs to the enoyl-CoA hydratase/isomerase family. (307 aa)
ACAT2Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. (397 aa)
SBSPONSomatomedin B and thrombospondin type 1 domain containing. (264 aa)
ACSM6Acyl-CoA synthetase medium chain family member 6. (480 aa)
ACSL4Acyl-CoA synthetase long-chain family member 4. (749 aa)
ECH1Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial isoform X1. (328 aa)
ECHS1Enoyl CoA hydratase, short chain, 1, mitochondrial; Belongs to the enoyl-CoA hydratase/isomerase family. (291 aa)
ACSL5Acyl-CoA synthetase long-chain family member 5. (739 aa)
CPT1BCPT1B isoform 2; Belongs to the carnitine/choline acetyltransferase family. (772 aa)
CBR4Carbonyl reductase 4. (237 aa)
CPT1CCarnitine palmitoyltransferase 1C; Belongs to the carnitine/choline acetyltransferase family. (803 aa)
CARTPTCART prepropeptide. (116 aa)
PECRPeroxisomal trans-2-enoyl-CoA reductase. (322 aa)
SLC27A1Solute carrier family 27 (Fatty acid transporter), member 1. (646 aa)
ACADMMedium-chain specific acyl-CoA dehydrogenase, mitochondrial; Acyl-CoA dehydrogenase specific for acyl chain lengths of 4 to 16 that catalyzes the initial step of fatty acid beta-oxidation. Utilizes the electron transfer flavoprotein (ETF) as an electron acceptor to transfer electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase). (412 aa)
ACSM2A-2Acyl-CoA synthetase medium chain family member 2A. (578 aa)
ETFDHElectron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. (617 aa)
L1TD1L1TD1 isoform 1. (864 aa)
HSDL2Hydroxysteroid dehydrogenase-like protein 2. (418 aa)
LOC745547CDY1B isoform 1. (541 aa)
HTD2Ribonuclease P/MRP 14kDa subunit. (164 aa)
ENSPTRP00000060782annotation not available (556 aa)
ENSPTRP00000061578annotation not available (78 aa)
HADHHydroxyacyl-CoA dehydrogenase. (390 aa)
LOC100612090Trifunctional enzyme subunit alpha, mitochondrial pseudogene. (647 aa)
ACOX3Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (712 aa)
HSD17B4Hydroxysteroid (17-beta) dehydrogenase 4. (809 aa)
DHTKD1Dehydrogenase E1 and transketolase domain containing 1. (919 aa)
ENSPTRP00000066028annotation not available (720 aa)
PCCBPropionyl-CoA carboxylase subunit beta. (570 aa)
ACADVLAcyl-CoA dehydrogenase, very long chain. (677 aa)
ACOX1Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (660 aa)
AASSAminoadipate-semialdehyde synthase. (926 aa)
ETFBElectron transfer flavoprotein subunit beta. (346 aa)
ACOXLACOXL isoform 9. (279 aa)
CPT1ACarnitine palmitoyltransferase 1A (Liver); Belongs to the carnitine/choline acetyltransferase family. (773 aa)
IVDIsovaleryl-CoA dehydrogenase. (426 aa)
ACACAAcetyl-CoA carboxylase alpha. (2383 aa)
BDH13-hydroxybutyrate dehydrogenase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (343 aa)
ACSF3ACSF3 isoform 1. (576 aa)
ACADSBAcyl-CoA dehydrogenase, short/branched chain. (434 aa)
ENSPTRP00000077599Acetoacetyl-CoA synthetase-like. (220 aa)
ACACBACACB isoform 2. (2458 aa)
SCP2D1SCP2D1 isoform 1. (160 aa)
CK820_G0051181T0181245 isoform 1. (149 aa)
AASDHAminoadipate-semialdehyde dehydrogenase. (1098 aa)
CK820_G0015962ACACB isoform 16. (191 aa)
LOC744070Testis-specific chromodomain protein Y 1. (556 aa)
CK820_G0041188OLAH isoform 7. (137 aa)
SLC27A4Solute carrier family 27 (Fatty acid transporter), member 4. (646 aa)
OXCT1Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (557 aa)
BTDBTD isoform 4. (545 aa)
OXSM3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial; May play a role in the biosynthesis of lipoic acid as well as longer chain fatty acids required for optimal mitochondrial function. Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (459 aa)
HSD17B14Hydroxysteroid (17-beta) dehydrogenase 14. (253 aa)
SMIM24Small integral membrane protein 24. (130 aa)
OLAHOLAH isoform 2. (312 aa)
ENSPTRP00000087701annotation not available (453 aa)
ENSPTRP00000089862annotation not available (350 aa)
ACSF2Acyl-CoA synthetase family member 2. (640 aa)
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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