12 items (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PLXNA2	PLXNA2 isoform 1. (1909 aa)
	WNT3-2	Wnt family member 3. (290 aa)
	SHH	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (465 aa)
	SOX4	Transcription factor SOX. (474 aa)
	COL2A1	Collagen type II alpha 1 chain. (1487 aa)
	SEMA3C	SEMA3C isoform 1; Belongs to the semaphorin family. (751 aa)
	SOX9	Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219. (509 aa)
	WNT3	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
	FGFR2	Fibroblast growth factor receptor. (841 aa)
	FGF10	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
	ZNF219	Zinc finger protein 219. (722 aa)
	SOX11	Transcription factor SOX. (441 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
COL2A1	SOX9	ENSPTRP00000041995	ENSPTRP00000016293	Collagen type II alpha 1 chain.	Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219.	0.819
FGF10	FGFR2	ENSPTRP00000083399	ENSPTRP00000005308	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor receptor.	0.996
FGF10	SHH	ENSPTRP00000083399	ENSPTRP00000075730	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.809
FGF10	SOX9	ENSPTRP00000083399	ENSPTRP00000016293	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219.	0.536
FGFR2	FGF10	ENSPTRP00000005308	ENSPTRP00000083399	Fibroblast growth factor receptor.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.996
FGFR2	SHH	ENSPTRP00000005308	ENSPTRP00000075730	Fibroblast growth factor receptor.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.545
PLXNA2	SEMA3C	ENSPTRP00000003263	ENSPTRP00000033095	PLXNA2 isoform 1.	SEMA3C isoform 1; Belongs to the semaphorin family.	0.801
SEMA3C	PLXNA2	ENSPTRP00000033095	ENSPTRP00000003263	SEMA3C isoform 1; Belongs to the semaphorin family.	PLXNA2 isoform 1.	0.801
SHH	FGF10	ENSPTRP00000075730	ENSPTRP00000083399	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.809
SHH	FGFR2	ENSPTRP00000075730	ENSPTRP00000005308	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Fibroblast growth factor receptor.	0.545
SHH	SOX9	ENSPTRP00000075730	ENSPTRP00000016293	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219.	0.648
SHH	WNT3	ENSPTRP00000075730	ENSPTRP00000015851	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.418
SHH	WNT3-2	ENSPTRP00000075730	ENSPTRP00000078190	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Wnt family member 3.	0.419
SOX4	SOX9	ENSPTRP00000050537	ENSPTRP00000016293	Transcription factor SOX.	Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219.	0.555
SOX9	COL2A1	ENSPTRP00000016293	ENSPTRP00000041995	Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219.	Collagen type II alpha 1 chain.	0.819
SOX9	FGF10	ENSPTRP00000016293	ENSPTRP00000083399	Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.536
SOX9	SHH	ENSPTRP00000016293	ENSPTRP00000075730	Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.648
SOX9	SOX4	ENSPTRP00000016293	ENSPTRP00000050537	Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219.	Transcription factor SOX.	0.555
SOX9	ZNF219	ENSPTRP00000016293	ENSPTRP00000092986	Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219.	Zinc finger protein 219.	0.404
WNT3	SHH	ENSPTRP00000015851	ENSPTRP00000075730	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.418