(23 nodes) Zinc finger, RanBP2-type network (Pan troglodytes)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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Predicted Interactions

gene neighborhood

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Your Input:
	ZRANB1	Zinc finger, RAN-binding domain containing 1. (734 aa)
	YAF2	YY1 associated factor 2. (204 aa)
	TAF15	TAF15 isoform 12. (603 aa)
	RANBP2-2	E3 SUMO-protein ligase RanBP2; E3 SUMO-protein ligase which facilitates SUMO1 and SUMO2 conjugation by UBE2I. Involved in transport factor (Ran-GTP, karyopherin)-mediated protein import via the F-G repeat-containing domain which acts as a docking site for substrates. Component of the nuclear export pathway. Specific docking site for the nuclear export factor exportin-1. Sumoylates PML at 'Lys-490' which is essential for the proper assembly of PML-NB. Recruits BICD2 to the nuclear envelope and cytoplasmic stacks of nuclear pore complex known as annulate lamellae during G2 phase of cell [...] (439 aa)
	ZRANB3	Zinc finger, RAN-binding domain containing 3. (1079 aa)
	RBCK1	RANBP2-type and C3HC4-type zinc finger containing 1. (510 aa)
	NEIL3	Nei endonuclease VIII-like 3. (607 aa)
	TAB2	TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (693 aa)
	TAB3	TGF-beta activated kinase 1 (MAP3K7) binding protein 3. (712 aa)
	MDM4	Protein Mdm4; Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Belongs to the MDM2/MDM4 family. (490 aa)
	FUS	FUS isoform 7. (526 aa)
	ZRANB2	Zinc finger Ran-binding domain-containing protein 2; May interfere with constitutive 5'-splice site selection. Belongs to the ZRANB2 family. (330 aa)
	SHARPIN	SHANK-associated RH domain interactor. (387 aa)
	MDM2	E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (499 aa)
	TEX13A	Testis expressed 13A. (409 aa)
	NUP153	NUP153 isoform 1. (1506 aa)
	NPLOC4	NPL4 homolog, ubiquitin recognition factor. (608 aa)
	RBM5	RNA binding motif protein 5. (823 aa)
	CAPN15	Small optic lobes homolog; Belongs to the peptidase C2 family. (1139 aa)
	RYBP	RYBP isoform 2. (228 aa)
	TEX13D	TEX13D isoform 2. (715 aa)
	RBM10	RNA binding motif protein 10. (1006 aa)
	EWSR1	EWS RNA binding protein 1. (661 aa)

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EWSR1	FUS	ENSPTRP00000088496	ENSPTRP00000053592	EWS RNA binding protein 1.	FUS isoform 7.	0.833
EWSR1	RBM10	ENSPTRP00000088496	ENSPTRP00000087039	EWS RNA binding protein 1.	RNA binding motif protein 10.	0.471
EWSR1	RBM5	ENSPTRP00000088496	ENSPTRP00000070980	EWS RNA binding protein 1.	RNA binding motif protein 5.	0.527
EWSR1	TAF15	ENSPTRP00000088496	ENSPTRP00000015400	EWS RNA binding protein 1.	TAF15 isoform 12.	0.492
FUS	EWSR1	ENSPTRP00000053592	ENSPTRP00000088496	FUS isoform 7.	EWS RNA binding protein 1.	0.833
FUS	RBM10	ENSPTRP00000053592	ENSPTRP00000087039	FUS isoform 7.	RNA binding motif protein 10.	0.403
FUS	RBM5	ENSPTRP00000053592	ENSPTRP00000070980	FUS isoform 7.	RNA binding motif protein 5.	0.422
FUS	TAF15	ENSPTRP00000053592	ENSPTRP00000015400	FUS isoform 7.	TAF15 isoform 12.	0.742
MDM2	SHARPIN	ENSPTRP00000062868	ENSPTRP00000059370	E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family.	SHANK-associated RH domain interactor.	0.457
NEIL3	RBM10	ENSPTRP00000028509	ENSPTRP00000087039	Nei endonuclease VIII-like 3.	RNA binding motif protein 10.	0.436
NPLOC4	TAB2	ENSPTRP00000068574	ENSPTRP00000031895	NPL4 homolog, ubiquitin recognition factor.	TGF-beta activated kinase 1 (MAP3K7) binding protein 2.	0.540
NPLOC4	TAB3	ENSPTRP00000068574	ENSPTRP00000047463	NPL4 homolog, ubiquitin recognition factor.	TGF-beta activated kinase 1 (MAP3K7) binding protein 3.	0.499
NPLOC4	ZRANB1	ENSPTRP00000068574	ENSPTRP00000005350	NPL4 homolog, ubiquitin recognition factor.	Zinc finger, RAN-binding domain containing 1.	0.603
NUP153	RANBP2-2	ENSPTRP00000068239	ENSPTRP00000021122	NUP153 isoform 1.	E3 SUMO-protein ligase RanBP2; E3 SUMO-protein ligase which facilitates SUMO1 and SUMO2 conjugation by UBE2I. Involved in transport factor (Ran-GTP, karyopherin)-mediated protein import via the F-G repeat-containing domain which acts as a docking site for substrates. Component of the nuclear export pathway. Specific docking site for the nuclear export factor exportin-1. Sumoylates PML at 'Lys-490' which is essential for the proper assembly of PML-NB. Recruits BICD2 to the nuclear envelope and cytoplasmic stacks of nuclear pore complex known as annulate lamellae during G2 phase of cell [...]	0.991
RANBP2-2	NUP153	ENSPTRP00000021122	ENSPTRP00000068239	E3 SUMO-protein ligase RanBP2; E3 SUMO-protein ligase which facilitates SUMO1 and SUMO2 conjugation by UBE2I. Involved in transport factor (Ran-GTP, karyopherin)-mediated protein import via the F-G repeat-containing domain which acts as a docking site for substrates. Component of the nuclear export pathway. Specific docking site for the nuclear export factor exportin-1. Sumoylates PML at 'Lys-490' which is essential for the proper assembly of PML-NB. Recruits BICD2 to the nuclear envelope and cytoplasmic stacks of nuclear pore complex known as annulate lamellae during G2 phase of cell [...]	NUP153 isoform 1.	0.991
RANBP2-2	ZRANB2	ENSPTRP00000021122	ENSPTRP00000056769	E3 SUMO-protein ligase RanBP2; E3 SUMO-protein ligase which facilitates SUMO1 and SUMO2 conjugation by UBE2I. Involved in transport factor (Ran-GTP, karyopherin)-mediated protein import via the F-G repeat-containing domain which acts as a docking site for substrates. Component of the nuclear export pathway. Specific docking site for the nuclear export factor exportin-1. Sumoylates PML at 'Lys-490' which is essential for the proper assembly of PML-NB. Recruits BICD2 to the nuclear envelope and cytoplasmic stacks of nuclear pore complex known as annulate lamellae during G2 phase of cell [...]	Zinc finger Ran-binding domain-containing protein 2; May interfere with constitutive 5'-splice site selection. Belongs to the ZRANB2 family.	0.428
RBCK1	SHARPIN	ENSPTRP00000022503	ENSPTRP00000059370	RANBP2-type and C3HC4-type zinc finger containing 1.	SHANK-associated RH domain interactor.	0.999
RBCK1	TAB2	ENSPTRP00000022503	ENSPTRP00000031895	RANBP2-type and C3HC4-type zinc finger containing 1.	TGF-beta activated kinase 1 (MAP3K7) binding protein 2.	0.637
RBCK1	TAB3	ENSPTRP00000022503	ENSPTRP00000047463	RANBP2-type and C3HC4-type zinc finger containing 1.	TGF-beta activated kinase 1 (MAP3K7) binding protein 3.	0.586
RBM10	EWSR1	ENSPTRP00000087039	ENSPTRP00000088496	RNA binding motif protein 10.	EWS RNA binding protein 1.	0.471