(5 nodes) Transmembrane protein 176A/B, and Membrane-spanning 4-domains subfamily A network (Homo sapiens)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MS4A15	Membrane-spanning 4-domains subfamily A member 15; May be involved in signal transduction as a component of a multimeric receptor complex. (240 aa)
	TMEM176B	Transmembrane protein 176B; May play a role in the process of maturation of dendritic cells. Required for the development of cerebellar granule cells (By similarity). (270 aa)
	TMEM176A	Transmembrane protein 176A. (235 aa)
	MS4A18	Membrane spanning 4-domains A18. (400 aa)
	MS4A14	Membrane-spanning 4-domains subfamily A member 14; May be involved in signal transduction as a component of a multimeric receptor complex. (712 aa)

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MS4A14	MS4A18	ENSP00000433761	ENSP00000431607	Membrane-spanning 4-domains subfamily A member 14; May be involved in signal transduction as a component of a multimeric receptor complex.	Membrane spanning 4-domains A18.	0.690
MS4A15	TMEM176A	ENSP00000386022	ENSP00000417626	Membrane-spanning 4-domains subfamily A member 15; May be involved in signal transduction as a component of a multimeric receptor complex.	Transmembrane protein 176A.	0.567
MS4A18	MS4A14	ENSP00000431607	ENSP00000433761	Membrane spanning 4-domains A18.	Membrane-spanning 4-domains subfamily A member 14; May be involved in signal transduction as a component of a multimeric receptor complex.	0.690
MS4A18	TMEM176A	ENSP00000431607	ENSP00000417626	Membrane spanning 4-domains A18.	Transmembrane protein 176A.	0.600
TMEM176A	MS4A15	ENSP00000417626	ENSP00000386022	Transmembrane protein 176A.	Membrane-spanning 4-domains subfamily A member 15; May be involved in signal transduction as a component of a multimeric receptor complex.	0.567
TMEM176A	MS4A18	ENSP00000417626	ENSP00000431607	Transmembrane protein 176A.	Membrane spanning 4-domains A18.	0.600
TMEM176A	TMEM176B	ENSP00000417626	ENSP00000410269	Transmembrane protein 176A.	Transmembrane protein 176B; May play a role in the process of maturation of dendritic cells. Required for the development of cerebellar granule cells (By similarity).	0.999
TMEM176B	TMEM176A	ENSP00000410269	ENSP00000417626	Transmembrane protein 176B; May play a role in the process of maturation of dendritic cells. Required for the development of cerebellar granule cells (By similarity).	Transmembrane protein 176A.	0.999