(16 nodes) Mixed, incl. Galactoside-binding lectin, and Transforming growth factor beta1 activation network (Homo sapiens)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LGALS2	Galectin-2; This protein binds beta-galactoside. Its physiological function is not yet known. (132 aa)
	LGALS13	Galactoside-binding soluble lectin 13; Binds beta-galactoside and lactose. Strong inducer of T-cell apoptosis. Has hemagglutinating activity towards chicken erythrocytes. (139 aa)
	CLC	Galectin-10; Regulates immune responses through the recognition of cell- surface glycans. Essential for the anergy and suppressive function of CD25-positive regulatory T-cells (Treg). (142 aa)
	PSG9	Pregnancy specific beta-1-glycoprotein 9. (426 aa)
	PSG6	Pregnancy specific beta-1-glycoprotein 6. (435 aa)
	PSG8	Pregnancy specific beta-1-glycoprotein 8. (426 aa)
	PSG1	Pregnancy specific beta-1-glycoprotein 1; Belongs to the immunoglobulin superfamily. CEA family. (428 aa)
	PSG11	Pregnancy specific beta-1-glycoprotein 11. (335 aa)
	OR4D11	Olfactory receptor 4D11; Odorant receptor; Belongs to the G-protein coupled receptor 1 family. (311 aa)
	PSG3	Pregnancy specific beta-1-glycoprotein 3; Belongs to the immunoglobulin superfamily. CEA family. (428 aa)
	PPEF1	Serine/threonine-protein phosphatase with EF-hands 1; May have a role in the recovery or adaptation response of photoreceptors. May have a role in development; Belongs to the PPP phosphatase family. (653 aa)
	PSG5	Pregnancy specific beta-1-glycoprotein 5; Belongs to the immunoglobulin superfamily. CEA family. (335 aa)
	PSG4	Pregnancy specific beta-1-glycoprotein 4. (419 aa)
	PSG2	Pregnancy specific beta-1-glycoprotein 2. (335 aa)
	ENDOU	Poly(U)-specific endoribonuclease; Endoribonuclease that cleaves single-stranded RNAs at uridylates and releases products that have 2'-3'-cyclic phosphate termini. (410 aa)
	PSG7	Pregnancy specific beta-1-glycoprotein 7. (297 aa)

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CLC	LGALS13	ENSP00000221804	ENSP00000221797	Galectin-10; Regulates immune responses through the recognition of cell- surface glycans. Essential for the anergy and suppressive function of CD25-positive regulatory T-cells (Treg).	Galactoside-binding soluble lectin 13; Binds beta-galactoside and lactose. Strong inducer of T-cell apoptosis. Has hemagglutinating activity towards chicken erythrocytes.	0.422
CLC	LGALS2	ENSP00000221804	ENSP00000215886	Galectin-10; Regulates immune responses through the recognition of cell- surface glycans. Essential for the anergy and suppressive function of CD25-positive regulatory T-cells (Treg).	Galectin-2; This protein binds beta-galactoside. Its physiological function is not yet known.	0.709
ENDOU	LGALS13	ENSP00000397679	ENSP00000221797	Poly(U)-specific endoribonuclease; Endoribonuclease that cleaves single-stranded RNAs at uridylates and releases products that have 2'-3'-cyclic phosphate termini.	Galactoside-binding soluble lectin 13; Binds beta-galactoside and lactose. Strong inducer of T-cell apoptosis. Has hemagglutinating activity towards chicken erythrocytes.	0.710
ENDOU	PPEF1	ENSP00000397679	ENSP00000354871	Poly(U)-specific endoribonuclease; Endoribonuclease that cleaves single-stranded RNAs at uridylates and releases products that have 2'-3'-cyclic phosphate termini.	Serine/threonine-protein phosphatase with EF-hands 1; May have a role in the recovery or adaptation response of photoreceptors. May have a role in development; Belongs to the PPP phosphatase family.	0.540
LGALS13	CLC	ENSP00000221797	ENSP00000221804	Galactoside-binding soluble lectin 13; Binds beta-galactoside and lactose. Strong inducer of T-cell apoptosis. Has hemagglutinating activity towards chicken erythrocytes.	Galectin-10; Regulates immune responses through the recognition of cell- surface glycans. Essential for the anergy and suppressive function of CD25-positive regulatory T-cells (Treg).	0.422
LGALS13	ENDOU	ENSP00000221797	ENSP00000397679	Galactoside-binding soluble lectin 13; Binds beta-galactoside and lactose. Strong inducer of T-cell apoptosis. Has hemagglutinating activity towards chicken erythrocytes.	Poly(U)-specific endoribonuclease; Endoribonuclease that cleaves single-stranded RNAs at uridylates and releases products that have 2'-3'-cyclic phosphate termini.	0.710
LGALS13	LGALS2	ENSP00000221797	ENSP00000215886	Galactoside-binding soluble lectin 13; Binds beta-galactoside and lactose. Strong inducer of T-cell apoptosis. Has hemagglutinating activity towards chicken erythrocytes.	Galectin-2; This protein binds beta-galactoside. Its physiological function is not yet known.	0.599
LGALS2	CLC	ENSP00000215886	ENSP00000221804	Galectin-2; This protein binds beta-galactoside. Its physiological function is not yet known.	Galectin-10; Regulates immune responses through the recognition of cell- surface glycans. Essential for the anergy and suppressive function of CD25-positive regulatory T-cells (Treg).	0.709
LGALS2	LGALS13	ENSP00000215886	ENSP00000221797	Galectin-2; This protein binds beta-galactoside. Its physiological function is not yet known.	Galactoside-binding soluble lectin 13; Binds beta-galactoside and lactose. Strong inducer of T-cell apoptosis. Has hemagglutinating activity towards chicken erythrocytes.	0.599
PPEF1	ENDOU	ENSP00000354871	ENSP00000397679	Serine/threonine-protein phosphatase with EF-hands 1; May have a role in the recovery or adaptation response of photoreceptors. May have a role in development; Belongs to the PPP phosphatase family.	Poly(U)-specific endoribonuclease; Endoribonuclease that cleaves single-stranded RNAs at uridylates and releases products that have 2'-3'-cyclic phosphate termini.	0.540
PSG1	PSG11	ENSP00000308970	ENSP00000319140	Pregnancy specific beta-1-glycoprotein 1; Belongs to the immunoglobulin superfamily. CEA family.	Pregnancy specific beta-1-glycoprotein 11.	0.502
PSG1	PSG2	ENSP00000308970	ENSP00000385706	Pregnancy specific beta-1-glycoprotein 1; Belongs to the immunoglobulin superfamily. CEA family.	Pregnancy specific beta-1-glycoprotein 2.	0.777
PSG1	PSG3	ENSP00000308970	ENSP00000332215	Pregnancy specific beta-1-glycoprotein 1; Belongs to the immunoglobulin superfamily. CEA family.	Pregnancy specific beta-1-glycoprotein 3; Belongs to the immunoglobulin superfamily. CEA family.	0.954
PSG1	PSG4	ENSP00000308970	ENSP00000384770	Pregnancy specific beta-1-glycoprotein 1; Belongs to the immunoglobulin superfamily. CEA family.	Pregnancy specific beta-1-glycoprotein 4.	0.907
PSG1	PSG5	ENSP00000308970	ENSP00000382334	Pregnancy specific beta-1-glycoprotein 1; Belongs to the immunoglobulin superfamily. CEA family.	Pregnancy specific beta-1-glycoprotein 5; Belongs to the immunoglobulin superfamily. CEA family.	0.806
PSG1	PSG6	ENSP00000308970	ENSP00000292125	Pregnancy specific beta-1-glycoprotein 1; Belongs to the immunoglobulin superfamily. CEA family.	Pregnancy specific beta-1-glycoprotein 6.	0.822
PSG1	PSG7	ENSP00000308970	ENSP00000485117	Pregnancy specific beta-1-glycoprotein 1; Belongs to the immunoglobulin superfamily. CEA family.	Pregnancy specific beta-1-glycoprotein 7.	0.849
PSG1	PSG8	ENSP00000308970	ENSP00000305005	Pregnancy specific beta-1-glycoprotein 1; Belongs to the immunoglobulin superfamily. CEA family.	Pregnancy specific beta-1-glycoprotein 8.	0.800
PSG1	PSG9	ENSP00000308970	ENSP00000270077	Pregnancy specific beta-1-glycoprotein 1; Belongs to the immunoglobulin superfamily. CEA family.	Pregnancy specific beta-1-glycoprotein 9.	0.942
PSG11	PSG1	ENSP00000319140	ENSP00000308970	Pregnancy specific beta-1-glycoprotein 11.	Pregnancy specific beta-1-glycoprotein 1; Belongs to the immunoglobulin superfamily. CEA family.	0.502